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The HCN domain couples voltage gating and cAMP response in hyperpolarization-activated cyclic nucleotide-gated channels.
Porro A, Saponaro A, Gasparri F, Bauer D, Gross C, Pisoni M, Abbandonato G, Hamacher K, Santoro B, Thiel G, Moroni A. Porro A, et al. Among authors: saponaro a. Elife. 2019 Nov 26;8:e49672. doi: 10.7554/eLife.49672. Elife. 2019. PMID: 31769408 Free PMC article.
A light-gated potassium channel for sustained neuronal inhibition.
Alberio L, Locarno A, Saponaro A, Romano E, Bercier V, Albadri S, Simeoni F, Moleri S, Pelucchi S, Porro A, Marcello E, Barsotti N, Kukovetz K, Boender AJ, Contestabile A, Luo S, Moutal A, Ji Y, Romani G, Beltrame M, Del Bene F, Di Luca M, Khanna R, Colecraft HM, Pasqualetti M, Thiel G, Tonini R, Moroni A. Alberio L, et al. Among authors: saponaro a. Nat Methods. 2018 Nov;15(11):969-976. doi: 10.1038/s41592-018-0186-9. Epub 2018 Oct 30. Nat Methods. 2018. PMID: 30377377 Free PMC article.
Mechanical transduction of cytoplasmic-to-transmembrane-domain movements in a hyperpolarization-activated cyclic nucleotide-gated cation channel.
Gross C, Saponaro A, Santoro B, Moroni A, Thiel G, Hamacher K. Gross C, et al. Among authors: saponaro a. J Biol Chem. 2018 Aug 17;293(33):12908-12918. doi: 10.1074/jbc.RA118.002139. Epub 2018 Jun 23. J Biol Chem. 2018. PMID: 29936413 Free PMC article.
A synthetic peptide that prevents cAMP regulation in mammalian hyperpolarization-activated cyclic nucleotide-gated (HCN) channels.
Saponaro A, Cantini F, Porro A, Bucchi A, DiFrancesco D, Maione V, Donadoni C, Introini B, Mesirca P, Mangoni ME, Thiel G, Banci L, Santoro B, Moroni A. Saponaro A, et al. Elife. 2018 Jun 20;7:e35753. doi: 10.7554/eLife.35753. Elife. 2018. PMID: 29923826 Free PMC article.
Protein Adsorption at the Air-Water Interface by a Charge Sensing Interferometric Technique.
Brocca P, Saponaro A, Introini B, Rondelli V, Pannuzzo M, Raciti D, Corti M, Raudino A. Brocca P, et al. Among authors: saponaro a. Langmuir. 2019 Dec 10;35(49):16087-16100. doi: 10.1021/acs.langmuir.9b02201. Epub 2019 Nov 19. Langmuir. 2019. PMID: 31693380 Free article.
A reduced mechanical model for cAMP-modulated gating in HCN channels.
Weißgraeber S, Saponaro A, Thiel G, Hamacher K. Weißgraeber S, et al. Among authors: saponaro a. Sci Rep. 2017 Jan 11;7:40168. doi: 10.1038/srep40168. Sci Rep. 2017. PMID: 28074902 Free PMC article.
cyclic AMP Regulation and Its Command in the Pacemaker Channel HCN4.
Porro A, Thiel G, Moroni A, Saponaro A. Porro A, et al. Among authors: saponaro a. Front Physiol. 2020 Jul 7;11:771. doi: 10.3389/fphys.2020.00771. eCollection 2020. Front Physiol. 2020. PMID: 32733276 Free PMC article. Review.
Fusicoccin Activates KAT1 Channels by Stabilizing Their Interaction with 14-3-3 Proteins.
Saponaro A, Porro A, Chaves-Sanjuan A, Nardini M, Rauh O, Thiel G, Moroni A. Saponaro A, et al. Plant Cell. 2017 Oct;29(10):2570-2580. doi: 10.1105/tpc.17.00375. Epub 2017 Sep 29. Plant Cell. 2017. PMID: 28970335 Free PMC article.
A Functional K+ Channel from Tetraselmis Virus 1, a Member of the Mimiviridae.
Kukovetz K, Hertel B, Schvarcz CR, Saponaro A, Manthey M, Burk U, Greiner T, Steward GF, Van Etten JL, Moroni A, Thiel G, Rauh O. Kukovetz K, et al. Among authors: saponaro a. Viruses. 2020 Sep 29;12(10):1107. doi: 10.3390/v12101107. Viruses. 2020. PMID: 33003637 Free PMC article.
Structural Basis of Inhibition of the Pioneer Transcription Factor NF-Y by Suramin.
Nardone V, Chaves-Sanjuan A, Lapi M, Airoldi C, Saponaro A, Pasqualato S, Dolfini D, Camilloni C, Bernardini A, Gnesutta N, Mantovani R, Nardini M. Nardone V, et al. Among authors: saponaro a. Cells. 2020 Oct 29;9(11):2370. doi: 10.3390/cells9112370. Cells. 2020. PMID: 33138093 Free PMC article.
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