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One-pot synthesis of substituted pyrrolo[3,4-b]pyridine-4,5-diones based on the reaction of N-(1-(4-hydroxy-6-methyl-2-oxo-2H-pyran-3-yl)-2-oxo-2-arylethyl)acetamide with amines.
Melekhina VG, Komogortsev AN, Lichitsky BV, Mityanov VS, Fakhrutdinov AN, Dudinov AA, Migulin VA, Nelyubina YV, Melnikova EK, Krayushkin MM. Melekhina VG, et al. Among authors: komogortsev an. Beilstein J Org Chem. 2019 Nov 25;15:2840-2846. doi: 10.3762/bjoc.15.277. eCollection 2019. Beilstein J Org Chem. 2019. PMID: 31839829 Free PMC article.
Benzimidazolyl-pyrazolo[3,4-b]pyridinones, Selective Inhibitors of MOLT-4 Leukemia Cell Growth and Sea Urchin Embryo Spiculogenesis: Target Quest.
Lichitsky BV, Komogortsev AN, Dudinov AA, Krayushkin MM, Khodot EN, Samet AV, Silyanova EA, Konyushkin LD, Karpov AS, Gorses D, Radimerski T, Semenova MN, Kiselyov AS, Semenov VV. Lichitsky BV, et al. Among authors: komogortsev an. ACS Comb Sci. 2019 Dec 9;21(12):805-816. doi: 10.1021/acscombsci.9b00135. Epub 2019 Nov 14. ACS Comb Sci. 2019. PMID: 31689077
Synthesis and anti-mitotic activity of 6,7-dihydro-4H-isothiazolo[4,5-b]pyridin-5-ones: In vivo and cell-based studies.
Semenov VV, Lichitsky BV, Komogortsev AN, Dudinov AA, Krayushkin MM, Konyushkin LD, Atamanenko OP, Karmanova IB, Strelenko YA, Shor B, Semenova MN, Kiselyov AS. Semenov VV, et al. Among authors: komogortsev an. Eur J Med Chem. 2017 Jan 5;125:573-585. doi: 10.1016/j.ejmech.2016.09.075. Epub 2016 Sep 24. Eur J Med Chem. 2017. PMID: 27718473