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Year Number of Results
2012 1
2013 3
2014 3
2015 3
2016 3
2017 3
2018 1
2019 2
2020 3
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18 results
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Page 1
Fragment-Based Screening of a Natural Product Library against 62 Potential Malaria Drug Targets Employing Native Mass Spectrometry.
Vu H, Pedro L, Mak T, McCormick B, Rowley J, Liu M, Di Capua A, Williams-Noonan B, Pham NB, Pouwer R, Nguyen B, Andrews KT, Skinner-Adams T, Kim J, Hol WGJ, Hui R, Crowther GJ, Van Voorhis WC, Quinn RJ. Vu H, et al. Among authors: Di Capua A. ACS Infect Dis. 2018 Apr 13;4(4):431-444. doi: 10.1021/acsinfecdis.7b00197. Epub 2018 Mar 3. ACS Infect Dis. 2018. PMID: 29436819 Free PMC article.
Synthesis and biological evaluation of a new class of benzothiazines as neuroprotective agents.
Mancini A, Chelini A, Di Capua A, Castelli L, Brogi S, Paolino M, Giuliani G, Cappelli A, Frosini M, Ricci L, Leonelli E, Giorgi G, Giordani A, Magistretti J, Anzini M. Mancini A, et al. Among authors: Di Capua A. Eur J Med Chem. 2017 Jan 27;126:614-630. doi: 10.1016/j.ejmech.2016.11.053. Epub 2016 Nov 27. Eur J Med Chem. 2017. PMID: 27923201
Synthesis and Biological Evaluation of Novel Neuroprotective Pyridazine Derivatives as Excitatory Amino Acid Transporter 2 (EAAT2) Activators.
Chelini A, Brogi S, Paolino M, Di Capua A, Cappelli A, Giorgi G, Farzad M, Di Cesare Mannelli L, Micheli L, Ghelardini C, Anzini M. Chelini A, et al. Among authors: Di Capua A. J Med Chem. 2017 Jun 22;60(12):5216-5221. doi: 10.1021/acs.jmedchem.7b00383. Epub 2017 May 31. J Med Chem. 2017. PMID: 28525717
Synthesis and biological evaluation of fluorinated 1,5-diarylpyrrole-3-alkoxyethyl ether derivatives as selective COX-2 inhibitors endowed with anti-inflammatory activity.
Di Capua A, Sticozzi C, Brogi S, Brindisi M, Cappelli A, Sautebin L, Rossi A, Pace S, Ghelardini C, Di Cesare Mannelli L, Valacchi G, Giorgi G, Giordani A, Poce G, Biava M, Anzini M. Di Capua A, et al. Eur J Med Chem. 2016 Feb 15;109:99-106. doi: 10.1016/j.ejmech.2015.12.044. Epub 2015 Dec 28. Eur J Med Chem. 2016. PMID: 26774035
Design, Synthesis, and Biological Evaluation of Imidazo[1,5-a]quinoline as Highly Potent Ligands of Central Benzodiazepine Receptors.
Cappelli A, Anzini M, Castriconi F, Grisci G, Paolino M, Braile C, Valenti S, Giuliani G, Vomero S, Di Capua A, Betti L, Giannaccini G, Lucacchini A, Ghelardini C, Di Cesare Mannelli L, Frosini M, Ricci L, Giorgi G, Mascia MP, Biggio G. Cappelli A, et al. Among authors: Di Capua A. J Med Chem. 2016 Apr 14;59(7):3353-72. doi: 10.1021/acs.jmedchem.6b00034. Epub 2016 Mar 24. J Med Chem. 2016. PMID: 26982523
Chondroprotective effect of three different classes of anti-inflammatory agents on human osteoarthritic chondrocytes exposed to IL-1β.
Cheleschi S, Pascarelli NA, Valacchi G, Di Capua A, Biava M, Belmonte G, Giordani A, Sticozzi C, Anzini M, Fioravanti A. Cheleschi S, et al. Among authors: Di Capua A. Int Immunopharmacol. 2015 Sep;28(1):794-801. doi: 10.1016/j.intimp.2015.07.003. Epub 2015 Aug 26. Int Immunopharmacol. 2015. PMID: 26292179
Synthesis, biological evaluation and molecular modeling of novel selective COX-2 inhibitors: sulfide, sulfoxide, and sulfone derivatives of 1,5-diarylpyrrol-3-substituted scaffold.
Reale A, Brogi S, Chelini A, Paolino M, Di Capua A, Giuliani G, Cappelli A, Giorgi G, Chemi G, Grillo A, Valoti M, Sautebin L, Rossi A, Pace S, La Motta C, Di Cesare Mannelli L, Lucarini E, Ghelardini C, Anzini M. Reale A, et al. Among authors: Di Capua A. Bioorg Med Chem. 2019 Oct 1;27(19):115045. doi: 10.1016/j.bmc.2019.115045. Epub 2019 Aug 9. Bioorg Med Chem. 2019. PMID: 31427145
Integrated Use of Biochemical, Native Mass Spectrometry, Computational, and Genome-Editing Methods to Elucidate the Mechanism of a Salmonella deglycase.
Sengupta A, Wu J, Seffernick JT, Sabag-Daigle A, Thomsen N, Chen TH, Capua AD, Bell CE, Ahmer BMM, Lindert S, Wysocki VH, Gopalan V. Sengupta A, et al. Among authors: Capua AD. J Mol Biol. 2019 Nov 8;431(22):4497-4513. doi: 10.1016/j.jmb.2019.08.017. Epub 2019 Sep 4. J Mol Biol. 2019. PMID: 31493410
Synthesis, biological evaluation and docking analysis of a new series of methylsulfonyl and sulfamoyl acetamides and ethyl acetates as potent COX-2 inhibitors.
Consalvi S, Alfonso S, Di Capua A, Poce G, Pirolli A, Sabatino M, Ragno R, Anzini M, Sartini S, La Motta C, Di Cesare Mannelli L, Ghelardini C, Biava M. Consalvi S, et al. Among authors: Di Capua A. Bioorg Med Chem. 2015 Feb 15;23(4):810-20. doi: 10.1016/j.bmc.2014.12.041. Epub 2014 Dec 26. Bioorg Med Chem. 2015. PMID: 25596758
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