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Therapeutic inhibition of inflammatory monocyte recruitment reduces steatohepatitis and liver fibrosis.

Krenkel O, Puengel T, Govaere O, Abdallah AT, Mossanen JC, Kohlhepp M, Liepelt A, Lefebvre E, Luedde T, Hellerbrand C, Weiskirchen R, Longerich T, Costa IG, Anstee QM, Trautwein C, Tacke F. Krenkel O, et al. Among authors: liepelt a. Hepatology. 2018 Apr;67(4):1270-1283. doi: 10.1002/hep.29544. Epub 2018 Feb 19. Hepatology. 2018. PMID: 28940700

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CXCR6 Inhibits Hepatocarcinogenesis by Promoting Natural Killer T- and CD4⁺ T-Cell-Dependent Control of Senescence.

Mossanen JC, Kohlhepp M, Wehr A, Krenkel O, Liepelt A, Roeth AA, Möckel D, Heymann F, Lammers T, Gassler N, Hermann J, Jankowski J, Neumann UP, Luedde T, Trautwein C, Tacke F. Mossanen JC, et al. Among authors: liepelt a. Gastroenterology. 2019 May;156(6):1877-1889.e4. doi: 10.1053/j.gastro.2019.01.247. Epub 2019 Jan 30. Gastroenterology. 2019. PMID: 30710528

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Stromal cell-derived factor-1 (SDF-1) as a target in liver diseases.

Liepelt A, Tacke F. Liepelt A, et al. Am J Physiol Gastrointest Liver Physiol. 2016 Aug 1;311(2):G203-9. doi: 10.1152/ajpgi.00193.2016. Epub 2016 Jun 16. Am J Physiol Gastrointest Liver Physiol. 2016. PMID: 27313175 Free article. Review.

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CXCR6 protects from inflammation and fibrosis in NEMO^LPC-KO mice.

Liepelt A, Wehr A, Kohlhepp M, Mossanen JC, Kreggenwinkel K, Denecke B, Costa IG, Luedde T, Trautwein C, Tacke F. Liepelt A, et al. Biochim Biophys Acta Mol Basis Dis. 2019 Feb 1;1865(2):391-402. doi: 10.1016/j.bbadis.2018.11.020. Epub 2018 Nov 24. Biochim Biophys Acta Mol Basis Dis. 2019. PMID: 30476545 Free article.

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miR-155 targets Caspase-3 mRNA in activated macrophages.

De Santis R, Liepelt A, Mossanen JC, Dueck A, Simons N, Mohs A, Trautwein C, Meister G, Marx G, Ostareck-Lederer A, Ostareck DH. De Santis R, et al. Among authors: liepelt a. RNA Biol. 2016;13(1):43-58. doi: 10.1080/15476286.2015.1109768. RNA Biol. 2016. PMID: 26574931 Free PMC article.

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Elevated circulating CD14⁺⁺CD16⁺ intermediate monocytes are independently associated with extracardiac complications after cardiac surgery.

Mossanen JC, Jansen TU, Pracht J, Liepelt A, Buendgens L, Stoppe C, Goetzenich A, Simon TP, Autschbach R, Marx G, Tacke F. Mossanen JC, et al. Among authors: liepelt a. Sci Rep. 2020 Jan 22;10(1):947. doi: 10.1038/s41598-020-57700-9. Sci Rep. 2020. PMID: 31969629 Free PMC article.

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CX₃CR1 Mediates the Development of Monocyte-Derived Dendritic Cells during Hepatic Inflammation.

Sutti S, Bruzzì S, Heymann F, Liepelt A, Krenkel O, Toscani A, Ramavath NN, Cotella D, Albano E, Tacke F. Sutti S, et al. Among authors: liepelt a. Cells. 2019 Sep 18;8(9):1099. doi: 10.3390/cells8091099. Cells. 2019. PMID: 31540356 Free PMC article.

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Differential Gene Expression in Circulating CD14⁺ Monocytes Indicates the Prognosis of Critically Ill Patients with Sepsis.

Liepelt A, Hohlstein P, Gussen H, Xue J, Aschenbrenner AC, Ulas T, Buendgens L, Warzecha KT, Bartneck M, Luedde T, Trautwein C, Schultze JL, Koch A, Tacke F. Liepelt A, et al. J Clin Med. 2020 Jan 2;9(1):127. doi: 10.3390/jcm9010127. J Clin Med. 2020. PMID: 31906585 Free PMC article.

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Identification of RNA-binding Proteins in Macrophages by Interactome Capture.

Liepelt A, Naarmann-de Vries IS, Simons N, Eichelbaum K, Föhr S, Archer SK, Castello A, Usadel B, Krijgsveld J, Preiss T, Marx G, Hentze MW, Ostareck DH, Ostareck-Lederer A. Liepelt A, et al. Mol Cell Proteomics. 2016 Aug;15(8):2699-714. doi: 10.1074/mcp.M115.056564. Epub 2016 Jun 8. Mol Cell Proteomics. 2016. PMID: 27281784 Free PMC article.

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The CCR2⁺ Macrophage Subset Promotes Pathogenic Angiogenesis for Tumor Vascularization in Fibrotic Livers.

Bartneck M, Schrammen PL, Möckel D, Govaere O, Liepelt A, Krenkel O, Ergen C, McCain MV, Eulberg D, Luedde T, Trautwein C, Kiessling F, Reeves H, Lammers T, Tacke F. Bartneck M, et al. Among authors: liepelt a. Cell Mol Gastroenterol Hepatol. 2019;7(2):371-390. doi: 10.1016/j.jcmgh.2018.10.007. Epub 2018 Oct 18. Cell Mol Gastroenterol Hepatol. 2019. PMID: 30704985 Free PMC article.

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