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Page 1
Polyphenols from Bee Pollen: Structure, Absorption, Metabolism and Biological Activity.
Rzepecka-Stojko A, Stojko J, Kurek-Górecka A, Górecki M, Kabała-Dzik A, Kubina R, Moździerz A, Buszman E. Rzepecka-Stojko A, et al. Molecules. 2015 Dec 4;20(12):21732-49. doi: 10.3390/molecules201219800. Molecules. 2015. PMID: 26690100 Free PMC article. Review.
As regards flavonoids, essential structural elements are hydroxyl groups at the C5 and C7 positions in the A ring, and at the C3' and C4' positions in the B ring, and a hydroxyl group at the C3 position in the C ring. ...
As regards flavonoids, essential structural elements are hydroxyl groups at the C5 and C7 positions in the A ring, and at the C3' and …
Managing and preventing atypical hemolytic uremic syndrome recurrence after kidney transplantation.
Noris M, Remuzzi G. Noris M, et al. Curr Opin Nephrol Hypertens. 2013 Nov;22(6):704-12. doi: 10.1097/MNH.0b013e328365b3fe. Curr Opin Nephrol Hypertens. 2013. PMID: 24076560 Review.
More recent data have provided evidence about the efficacy of the anti-C5 monoclonal antibody eculizumab in the prevention and treatment of posttransplant aHUS recurrences. ...
More recent data have provided evidence about the efficacy of the anti-C5 monoclonal antibody eculizumab in the prevention and treatm …
[DNA tandem lesion: 5',8-cyclo-2'-deoxyadenosine. The influence on human health].
Merecz A, Karwowski BT. Merecz A, et al. Mol Biol (Mosk). 2016 Nov-Dec;50(6):899-905. doi: 10.7868/S0026898416050128. Mol Biol (Mosk). 2016. PMID: 28064306 Free article. Review. Russian.
Since clustered DNA damage is defined as the presence of two or more lesions in one helix turn, purine 5',8-cyclo-2'-deoxynucleosides are recognized as tandem lesions: both sugar moieties and base have been modified within one nucleoside/nucleotide. The hydrogen abstraction from …
Since clustered DNA damage is defined as the presence of two or more lesions in one helix turn, purine 5',8-cyclo-2'-deoxynucleosides are re …
Pharmacokinetic and Pharmacodynamic Properties of Cemdisiran, an RNAi Therapeutic Targeting Complement Component 5, in Healthy Subjects and Patients with Paroxysmal Nocturnal Hemoglobinuria.
Badri P, Jiang X, Borodovsky A, Najafian N, Kim J, Clausen VA, Goel V, Habtemariam B, Robbie GJ. Badri P, et al. Clin Pharmacokinet. 2021 Mar;60(3):365-378. doi: 10.1007/s40262-020-00940-9. Clin Pharmacokinet. 2021. PMID: 33047216 Free PMC article. Clinical Trial.
AS(N-2)3'-cemdisiran exhibited more than dose-proportional PK. The C5 protein reductions were dose-dependent, with > 90% reduction of C5 protein beginning on days 21-28 and maintained for 10-13 months following single and biweekly doses of 600 mg. ...One of 48 su …
AS(N-2)3'-cemdisiran exhibited more than dose-proportional PK. The C5 protein reductions were dose-dependent, with > 90% reduction …
Results of a phase 1/2 study of cemdisiran in healthy subjects and patients with paroxysmal nocturnal hemoglobinuria.
Gaya A, Munir T, Urbano-Ispizua A, Griffin M, Taubel J, Bush J, Bhan I, Borodovsky A, Wang Y, Badri P, Garg P. Gaya A, et al. EJHaem. 2023 Jun 26;4(3):612-624. doi: 10.1002/jha2.748. eCollection 2023 Aug. EJHaem. 2023. PMID: 37601837 Free PMC article.
Cemdisiran, an RNA interference investigational treatment, silences complement component 5 (C5) expression in the liver. Previously reported results showed sustained reduction in C5 levels following cemdisiran monotherapy, with >90% reduction in patients with PNH …
Cemdisiran, an RNA interference investigational treatment, silences complement component 5 (C5) expression in the liver. Previously r …
Functional outcome after transfer of brachialis on anterior interosseous and supinator on posterior interosseous nerves: A preliminary report.
Sacco C, Olivi S, Visani J, Donati R, Veronesi V, Mencarani C, Capone C, Bizzocchi G, Kiekens C, De Bonis P, Scerrati A, Staffa G. Sacco C, et al. Microsurgery. 2022 Sep;42(6):577-585. doi: 10.1002/micr.30891. Epub 2022 Apr 28. Microsurgery. 2022. PMID: 35484858
We included 11 patients (14 limbs) with traumatic SCI resulting in C4 level tetraplegia in five patients, C5 in four and C6 and C7 in one case each, with a median age of 31.5 years underwent surgery at a median of 10 months after injury; including both transfers in 10 case …
We included 11 patients (14 limbs) with traumatic SCI resulting in C4 level tetraplegia in five patients, C5 in four and C6 and C7 in …
49 results