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1,2,4-Triazolyl 5-Azaspiro[2.4]heptanes: Lead Identification and Early Lead Optimization of a New Series of Potent and Selective Dopamine D3 Receptor Antagonists.
Micheli F, Bacchi A, Braggio S, Castelletti L, Cavallini P, Cavanni P, Cremonesi S, Dal Cin M, Feriani A, Gehanne S, Kajbaf M, Marchió L, Nola S, Oliosi B, Pellacani A, Perdonà E, Sava A, Semeraro T, Tarsi L, Tomelleri S, Wong A, Visentini F, Zonzini L, Heidbreder C. Micheli F, et al. Among authors: pellacani a. J Med Chem. 2016 Sep 22;59(18):8549-76. doi: 10.1021/acs.jmedchem.6b00972. Epub 2016 Sep 9. J Med Chem. 2016. PMID: 27564135
2-Methyl-3-furanyl-4H-1,2,4-triazol-3-ylthioamides: a new class of selective orexin 2 antagonists.
Micheli F, Antolini M, Di Fabio R, Pellacani A, Pozzan A. Micheli F, et al. Among authors: pellacani a. Bioorg Med Chem Lett. 2010 Nov 15;20(22):6405-7. doi: 10.1016/j.bmcl.2010.09.090. Epub 2010 Sep 19. Bioorg Med Chem Lett. 2010. PMID: 20933413
Discovery process and pharmacological characterization of a novel dual orexin 1 and orexin 2 receptor antagonist useful for treatment of sleep disorders.
Di Fabio R, Pellacani A, Faedo S, Roth A, Piccoli L, Gerrard P, Porter RA, Johnson CN, Thewlis K, Donati D, Stasi L, Spada S, Stemp G, Nash D, Branch C, Kindon L, Massagrande M, Poffe A, Braggio S, Chiarparin E, Marchioro C, Ratti E, Corsi M. Di Fabio R, et al. Among authors: pellacani a. Bioorg Med Chem Lett. 2011 Sep 15;21(18):5562-7. doi: 10.1016/j.bmcl.2011.06.086. Epub 2011 Jun 30. Bioorg Med Chem Lett. 2011. PMID: 21831639
The antidepressant fluoxetine blocks the human small conductance calcium-activated potassium channels SK1, SK2 and SK3.
Terstappen GC, Pellacani A, Aldegheri L, Graziani F, Carignani C, Pula G, Virginio C. Terstappen GC, et al. Among authors: pellacani a. Neurosci Lett. 2003 Jul 31;346(1-2):85-8. doi: 10.1016/s0304-3940(03)00574-3. Neurosci Lett. 2003. PMID: 12850554
2-Aminopyridine Analogs Inhibit Both Enzymes of the Glyoxylate Shunt in Pseudomonas aeruginosa.
McVey AC, Bartlett S, Kajbaf M, Pellacani A, Gatta V, Tammela P, Spring DR, Welch M. McVey AC, et al. Among authors: pellacani a. Int J Mol Sci. 2020 Apr 3;21(7):2490. doi: 10.3390/ijms21072490. Int J Mol Sci. 2020. PMID: 32260167 Free PMC article.
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