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Oncogenes Activate an Autonomous Transcriptional Regulatory Circuit That Drives Glioblastoma.
Singh DK, Kollipara RK, Vemireddy V, Yang XL, Sun Y, Regmi N, Klingler S, Hatanpaa KJ, Raisanen J, Cho SK, Sirasanagandla S, Nannepaga S, Piccirillo S, Mashimo T, Wang S, Humphries CG, Mickey B, Maher EA, Zheng H, Kim RS, Kittler R, Bachoo RM. Singh DK, et al. Cell Rep. 2017 Jan 24;18(4):961-976. doi: 10.1016/j.celrep.2016.12.064. Cell Rep. 2017. PMID: 28122245 Free PMC article.
Acetate is a bioenergetic substrate for human glioblastoma and brain metastases.
Mashimo T, Pichumani K, Vemireddy V, Hatanpaa KJ, Singh DK, Sirasanagandla S, Nannepaga S, Piccirillo SG, Kovacs Z, Foong C, Huang Z, Barnett S, Mickey BE, DeBerardinis RJ, Tu BP, Maher EA, Bachoo RM. Mashimo T, et al. Cell. 2014 Dec 18;159(7):1603-14. doi: 10.1016/j.cell.2014.11.025. Cell. 2014. PMID: 25525878 Free PMC article.
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