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10,263 results

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The following term was not found in PubMed: Mariano-Melo
Page 1
A Randomized, Open-Label, Multiple-Dose, Parallel-Arm, Pivotal Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Aripiprazole 2-Month Long-Acting Injectable in Adults With Schizophrenia or Bipolar I Disorder.
Harlin M, Yildirim M, Such P, Madera-McDonough J, Jan M, Jin N, Watkin S, Larsen F. Harlin M, et al. CNS Drugs. 2023 Apr;37(4):337-350. doi: 10.1007/s40263-023-00996-8. Epub 2023 Mar 24. CNS Drugs. 2023. PMID: 36961650 Free PMC article. Clinical Trial.
The most frequently reported TEAEs were increased weight (Ari 2MRTU 960: 22.7%; AOM 400: 20.9%) and injection-site pain (Ari 2MRTU 960: 18.2%; AOM 400: 9.0%). ...The incidence of adverse events emerging during the treatment period was similar between Ari 2MRT …
The most frequently reported TEAEs were increased weight (Ari 2MRTU 960: 22.7%; AOM 400: 20.9%) and injection-site pain (Ari 2 …
Acquired resistance to immunotherapy in solid tumors.
Verdys P, Johansen AZ, Gupta A, Presti M, Dionisio E, Madsen DH, Curioni-Fontecedro A, Donia M. Verdys P, et al. Trends Mol Med. 2025 Nov;31(11):1008-1020. doi: 10.1016/j.molmed.2025.03.010. Epub 2025 Apr 23. Trends Mol Med. 2025. PMID: 40274520 Review.
Defining ARI clinically remains complex, but ongoing efforts aim to establish standardized criteria. ...Understanding the development of ARI is crucial for prevention and effective interventions. The integration of innovative strategies and translational research on …
Defining ARI clinically remains complex, but ongoing efforts aim to establish standardized criteria. ...Understanding the development …
Safety and Efficacy of Aripiprazole 2-Month Ready-to-Use 960 mg: Secondary Analysis of Outcomes in Adult Patients With Schizophrenia in a Randomized, Open-label, Parallel-Arm, Pivotal Study.
Citrome L, Such P, Yildirim M, Madera-McDonough J, Beckham C, Zhang Z, Larsen F, Harlin M. Citrome L, et al. J Clin Psychiatry. 2023 Sep 4;84(5):23m14873. doi: 10.4088/JCP.23m14873. J Clin Psychiatry. 2023. PMID: 37672016 Free article. Clinical Trial.
Results: Patients with schizophrenia were randomized to Ari 2MRTU 960 (n = 92) or AOM 400 (n = 93). The incidence of treatment-emergent adverse events (TEAEs) was similar between Ari 2MRTU 960 (66.3%) and AOM 400 (63.4%). ...Conclusions: Ari 2MRTU 960 was wel …
Results: Patients with schizophrenia were randomized to Ari 2MRTU 960 (n = 92) or AOM 400 (n = 93). The incidence of treatment-emerge …
Burden of respiratory syncytial virus infections in older adults with acute respiratory infection in Japan: An epidemiological study among outpatients.
Ohbayashi H, Sakurai T, Himeji D, Fukushima Y, Takahashi H, Kiyosue A, Sabater Cabrera E, Matsuki T, Molnar D, Preckler Moreno V, Damaso S, Pirçon JY, Moitinho de Almeida M. Ohbayashi H, et al. Respir Investig. 2024 Sep;62(5):914-921. doi: 10.1016/j.resinv.2024.06.003. Epub 2024 Aug 9. Respir Investig. 2024. PMID: 39126825 Free article.
HRQoL was assessed via patient-reported outcomes. RESULTS: The study included 923 ARI episodes (cRSV-ARI: N = 24; non-cRSV-ARI: N = 899). In years 1 and 2 (August 2021-July 2022 and August 2022-February 2023), the prevalence of cRSV-ARI was 2.5% and 2. …
HRQoL was assessed via patient-reported outcomes. RESULTS: The study included 923 ARI episodes (cRSV-ARI: N = 24; non-cRSV- …
Population Pharmacokinetics and Dosing Simulations for Aripiprazole 2-Month Ready-to-Use Long-Acting Injectable in Adult Patients With Schizophrenia or Bipolar I Disorder.
Wang Y, Harlin M, Larsen F, Wang X, Park W, Rich B, Gobburu JV, Raoufinia A. Wang Y, et al. Clin Pharmacol Drug Dev. 2024 Jun;13(6):631-643. doi: 10.1002/cpdd.1397. Epub 2024 Apr 11. Clin Pharmacol Drug Dev. 2024. PMID: 38602057
Aripiprazole plasma concentration-time profiles were simulated for various Ari RTU LAI initiation and maintenance scenarios in 1000 virtual patients. Diagnostic plots demonstrated that the final population pharmacokinetic model, which incorporated data for oral aripiprazol …
Aripiprazole plasma concentration-time profiles were simulated for various Ari RTU LAI initiation and maintenance scenarios in 1000 v …
Long-term clinical outcomes after hospitalization for acute respiratory illness due to respiratory syncytial virus (RSV).
Singer D, Wang Y, La EM, Gerber SI, Wu A, Betts KA. Singer D, et al. Clin Infect Dis. 2025 Dec 23:ciaf710. doi: 10.1093/cid/ciaf710. Online ahead of print. Clin Infect Dis. 2025. PMID: 41432364
BACKGROUND: Acute respiratory illnesses (ARI) can be severe in older adults and adults with chronic conditions. We compared long-term outcomes of United States patients aged 50 years with 1 hospitalized acute-respiratory illness due to respiratory syncytial virus (RSV- …
BACKGROUND: Acute respiratory illnesses (ARI) can be severe in older adults and adults with chronic conditions. We compared long-term …
Anthropometrics, Metabolic Syndrome, and Mortality Hazard.
Krakauer NY, Krakauer JC. Krakauer NY, et al. J Obes. 2018 Jul 12;2018:9241904. doi: 10.1155/2018/9241904. eCollection 2018. J Obes. 2018. PMID: 30123583 Free PMC article.
Baseline values of ARI and MS were also evaluated for their association with mortality over approximately 20 years of follow-up. ...ARI and MS were both significant predictors of mortality hazard. Although the association of ARI with mortality hazard was stro …
Baseline values of ARI and MS were also evaluated for their association with mortality over approximately 20 years of follow-up. ... …
Advanced Research Institute (ARI): Supporting the Geriatric Mental Health Research Pipeline.
Sirey JA, Pepin R, Aizenstein H, Taylor WD, Forester B, Okereke O, Byers AL, Bruce ML. Sirey JA, et al. Am J Geriatr Psychiatry. 2023 Dec;31(12):1209-1215. doi: 10.1016/j.jagp.2023.07.017. Epub 2023 Aug 5. Am J Geriatr Psychiatry. 2023. PMID: 37620206 Free PMC article.
Since 2004, ARI has enrolled 184 Scholars from 61 institutions across 34 states. We describe the ARI components and assess the impact and outcomes of ARI on research careers of participants. ...Given the struggle to reduce attrition from the research career p …
Since 2004, ARI has enrolled 184 Scholars from 61 institutions across 34 states. We describe the ARI components and assess the …
Aripiprazole-Associated Hypoprolactinemia in the Clinical Setting.
Sogawa R, Shimomura Y, Minami C, Maruo J, Kunitake Y, Mizoguchi Y, Kawashima T, Monji A, Hara H. Sogawa R, et al. J Clin Psychopharmacol. 2016 Aug;36(4):385-7. doi: 10.1097/JCP.0000000000000527. J Clin Psychopharmacol. 2016. PMID: 27281387
RESULTS: The incidence of hypoprolactinemia in the current study was 44.0% (11/25). Eighteen patients were treated with ARI alone and 7 received ARI in combination with other antipsychotics. The PRL value of patients who took ARI alone was significantly lower …
RESULTS: The incidence of hypoprolactinemia in the current study was 44.0% (11/25). Eighteen patients were treated with ARI alone and …
Aripiprazole for Tourette's syndrome: a systematic review and meta-analysis.
Zheng W, Li XB, Xiang YQ, Zhong BL, Chiu HF, Ungvari GS, Ng CH, Lok GK, Xiang YT. Zheng W, et al. Hum Psychopharmacol. 2016 Jan;31(1):11-8. doi: 10.1002/hup.2498. Epub 2015 Aug 26. Hum Psychopharmacol. 2016. PMID: 26310194
CONCLUSION: This review found that ARI has similar efficacy to TIA and HAL for TS, while extrapyramidal symptoms were significantly less with ARI than with HAL. ARI can be considered as an alternative treatment option for TS....
CONCLUSION: This review found that ARI has similar efficacy to TIA and HAL for TS, while extrapyramidal symptoms were significantly l …
10,263 results
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