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Generation of recombinant hyperimmune globulins from diverse B-cell repertoires.
Keating SM, Mizrahi RA, Adams MS, Asensio MA, Benzie E, Carter KP, Chiang Y, Edgar RC, Gautam BK, Gras A, Leong J, Leong R, Lim YW, Manickam VA, Medina-Cucurella AV, Niedecken AR, Saini J, Simons JF, Spindler MJ, Stadtmiller K, Tinsley B, Wagner EK, Wayham N, Tracy L, Lundberg CV, Büscher D, Terencio JV, Roalfe L, Pearce E, Richardson H, Goldblatt D, Ramjag AT, Carrington CVF, Simmons G, Muench MO, Chamow SM, Monroe B, Olson C, Oguin TH, Lynch H, Jeanfreau R, Mosher RA, Walch MJ, Bartley CR, Ross CA, Meyer EH, Adler AS, Johnson DS. Keating SM, et al. Among authors: niedecken ar. Nat Biotechnol. 2021 Aug;39(8):989-999. doi: 10.1038/s41587-021-00894-8. Epub 2021 Apr 15. Nat Biotechnol. 2021. PMID: 33859400 Free PMC article.
GMP Manufacturing and IND-Enabling Studies of a Recombinant Hyperimmune Globulin Targeting SARS-CoV-2.
Mizrahi RA, Lin WY, Gras A, Niedecken AR, Wagner EK, Keating SM, Ikon N, Manickam VA, Asensio MA, Leong J, Medina-Cucurella AV, Benzie E, Carter KP, Chiang Y, Edgar RC, Leong R, Lim YW, Simons JF, Spindler MJ, Stadtmiller K, Wayham N, Büscher D, Terencio JV, Germanio CD, Chamow SM, Olson C, Pino PA, Park JG, Hicks A, Ye C, Garcia-Vilanova A, Martinez-Sobrido L, Torrelles JB, Johnson DS, Adler AS. Mizrahi RA, et al. Among authors: niedecken ar. Pathogens. 2022 Jul 19;11(7):806. doi: 10.3390/pathogens11070806. Pathogens. 2022. PMID: 35890050 Free PMC article.
A Potent Recombinant Polyclonal Antibody Therapeutic for Protection Against New SARS-CoV-2 Variants of Concern.
Wayham NP, Niedecken AR, Simons JF, Chiang YY, Medina-Cucurella AV, Mizrahi RA, Wagner EK, Gras A, Segal I, Witte P, Enstrom A, Bountouvas A, Nelson SM, Weinberger T, Tan D, Asensio MA, Subramanian A, Lim YW, Adler AS, Keating SM. Wayham NP, et al. Among authors: niedecken ar. J Infect Dis. 2023 Apr 17:jiad102. doi: 10.1093/infdis/jiad102. Online ahead of print. J Infect Dis. 2023. PMID: 37062677
Preferential Identification of Agonistic OX40 Antibodies by Using Cell Lysate to Pan Natively Paired, Humanized Mouse-Derived Yeast Surface Display Libraries.
Medina-Cucurella AV, Mizrahi RA, Asensio MA, Edgar RC, Leong J, Leong R, Lim YW, Nelson A, Niedecken AR, Simons JF, Spindler MJ, Stadtmiller K, Wayham N, Adler AS, Johnson DS. Medina-Cucurella AV, et al. Among authors: niedecken ar. Antibodies (Basel). 2019 Feb 19;8(1):17. doi: 10.3390/antib8010017. Antibodies (Basel). 2019. PMID: 31544823 Free PMC article.