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Cryptotanshinone from the Salvia miltiorrhiza Bunge Attenuates Ethanol-Induced Liver Injury by Activation of AMPK/SIRT1 and Nrf2 Signaling Pathways.

Nagappan A, Kim JH, Jung DY, Jung MH. Nagappan A, et al. Int J Mol Sci. 2019 Dec 30;21(1):265. doi: 10.3390/ijms21010265. Int J Mol Sci. 2019. PMID: 31906014 Free PMC article.

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Role of Cannabinoid Receptor Type 1 in Insulin Resistance and Its Biological Implications.

Nagappan A, Shin J, Jung MH. Nagappan A, et al. Int J Mol Sci. 2019 Apr 29;20(9):2109. doi: 10.3390/ijms20092109. Int J Mol Sci. 2019. PMID: 31035653 Free PMC article. Review.

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Morin enhances auranofin anticancer activity by up-regulation of DR4 and DR5 and modulation of Bcl-2 through reactive oxygen species generation in Hep3B human hepatocellular carcinoma cells.

Hwang-Bo H, Lee WS, Nagappan A, Kim HJ, Panchanathan R, Park C, Chang SH, Kim ND, Leem SH, Chang YC, Kwon TK, Cheong JH, Kim GS, Jung JM, Shin SC, Hong SC, Choi YH. Hwang-Bo H, et al. Among authors: nagappan a. Phytother Res. 2019 May;33(5):1384-1393. doi: 10.1002/ptr.6329. Epub 2019 Mar 19. Phytother Res. 2019. PMID: 30887612

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Pretreatment of Anthocyanin from the Fruit of Vitis coignetiae Pulliat Acts as a Potent Inhibitor of TNF-α Effect by Inhibiting NF-κB-Regulated Genes in Human Breast Cancer Cells.

Paramanantham A, Kim MJ, Jung EJ, Nagappan A, Yun JW, Kim HJ, Shin SC, Kim GS, Lee WS. Paramanantham A, et al. Among authors: nagappan a. Molecules. 2020 May 21;25(10):2396. doi: 10.3390/molecules25102396. Molecules. 2020. PMID: 32455624 Free PMC article.

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Histone H3K9 demethylase JMJD2B induces hepatic steatosis through upregulation of PPARγ2.

Kim JH, Jung DY, Nagappan A, Jung MH. Kim JH, et al. Among authors: nagappan a. Sci Rep. 2018 Sep 13;8(1):13734. doi: 10.1038/s41598-018-31953-x. Sci Rep. 2018. PMID: 30214048 Free PMC article.

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Gomisin N Alleviates Ethanol-Induced Liver Injury through Ameliorating Lipid Metabolism and Oxidative Stress.

Nagappan A, Jung DY, Kim JH, Lee H, Jung MH. Nagappan A, et al. Int J Mol Sci. 2018 Sep 1;19(9):2601. doi: 10.3390/ijms19092601. Int J Mol Sci. 2018. PMID: 30200508 Free PMC article.

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Protective Effects of Gomisin N against Hepatic Cannabinoid Type 1 Receptor-Induced Insulin Resistance and Gluconeogenesis.

Nagappan A, Jung DY, Kim JH, Jung MH. Nagappan A, et al. Int J Mol Sci. 2018 Mar 23;19(4):968. doi: 10.3390/ijms19040968. Int J Mol Sci. 2018. PMID: 29570673 Free PMC article.

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Lonicera japonica Thunb. Induces caspase-dependent apoptosis through death receptors and suppression of AKT in U937 human leukemic cells.

Park C, Lee WS, Han MH, Song KS, Hong SH, Nagappan A, Kim GY, Kim GS, Jung JM, Ryu CH, Shin SC, Hong SC, Choi YH. Park C, et al. Among authors: nagappan a. Phytother Res. 2018 Mar;32(3):504-513. doi: 10.1002/ptr.5996. Epub 2017 Nov 29. Phytother Res. 2018. PMID: 29193390

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Polyphenolic compounds from Korean Lonicera japonica Thunb. induces apoptosis via AKT and caspase cascade activation in A549 cells.

Park KI, Park H, Nagappan A, Hong GE, Yumnam S, Lee HJ, Kim EH, Lee WS, Shin SC, Kim JA, Lee SJ, Ma JY, Min T, Heo JD, Kim GS. Park KI, et al. Among authors: nagappan a. Oncol Lett. 2017 Apr;13(4):2521-2530. doi: 10.3892/ol.2017.5771. Epub 2017 Feb 23. Oncol Lett. 2017. PMID: 28454429 Free PMC article.

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hesperidin induces paraptosis like cell death in hepatoblastoma, HepG2 Cells: involvement of ERK1/2 MAPK [corrected].

Yumnam S, Park HS, Kim MK, Nagappan A, Hong GE, Lee HJ, Lee WS, Kim EH, Cho JH, Shin SC, Kim GS. Yumnam S, et al. Among authors: nagappan a. PLoS One. 2014 Jun 30;9(6):e101321. doi: 10.1371/journal.pone.0101321. eCollection 2014. PLoS One. 2014. PMID: 24977707 Free PMC article.

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