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Page 1
Dog Models of Aging.
Ruple A, MacLean E, Snyder-Mackler N, Creevy KE, Promislow D. Ruple A, et al. Annu Rev Anim Biosci. 2022 Feb 15;10:419-439. doi: 10.1146/annurev-animal-051021-080937. Epub 2021 Oct 26. Annu Rev Anim Biosci. 2022. PMID: 34699257 Free PMC article. Review.
Canine sentinels and our shared exposome.
Sexton C, Ruple A. Sexton C, et al. Among authors: ruple a. Science. 2024 Jun 14;384(6701):1170-1172. doi: 10.1126/science.adl0426. Epub 2024 Jun 13. Science. 2024. PMID: 38870288
Veterinary Big Data: When Data Goes to the Dogs.
Paynter AN, Dunbar MD, Creevy KE, Ruple A. Paynter AN, et al. Among authors: ruple a. Animals (Basel). 2021 Jun 23;11(7):1872. doi: 10.3390/ani11071872. Animals (Basel). 2021. PMID: 34201681 Free PMC article. Review.
Immunological responses and clinical outcomes in dogs with osteosarcoma receiving standard therapy and a Listeria vaccine expressing HER2.
Mason NJ, Selmic L, Ruple A, London CA, Barber L, Weishaar K, Perry JA, Mahoney J, Flesner B, Bryan JN, Willcox JL, Burton JH, Vail DM, Kisseberth WC, Balkman CE, McCleary-Wheeler AL, Curran KM, Leeper H, Woods JP, Mutsaers AJ, Higginbotham ML, Wouda RM, Wilson-Robles H, Dervisis N, Saba C, MacDonald-Dickinson VS, Hess PR, Cherukuri A, Rotolo A, Beck JA, Patkar S, Mazcko C, LeBlanc AK. Mason NJ, et al. Among authors: ruple a. Mol Ther. 2025 Apr 2;33(4):1674-1686. doi: 10.1016/j.ymthe.2025.02.023. Epub 2025 Feb 15. Mol Ther. 2025. PMID: 39955616
Test of Rapamycin in Aging Dogs (TRIAD): study design and rationale for a prospective, parallel-group, double-masked, randomized, placebo-controlled, multicenter trial of rapamycin in healthy middle-aged dogs from the Dog Aging Project.
Coleman AE, Creevy KE, Anderson R, Reed MJ, Fajt VR, Aicher KM, Atiee G, Barnett BG, Baumwart RD, Boudreau B, Cunningham SM, Dunbar MD, Ditzler B, Ferguson AM, Forsyth KK, Gambino AN, Gordon SG, Hammond HK, Holland SN, Iannaccone MK, Illing K, Kadotani S, Knowles SA, MacLean EL, Maran BA, Markovic LE, McGrath S, Melvin RL, Mueller MS, Nelson OL, Olby NJ, Pancotto TE, Parsley E, Potter BM, Prescott JO, Saunders AB, Sawyer HM, Scansen BA, Schmid SM, Smith CC, Tjostheim SS, Tolbert MK, Tropf MA, Visser LC, Ward JL, Wesselowski SR, Windsor RC, Yang VK, Ruple A, Promislow DEL, Kaeberlein M; Dog Aging Project Consortium. Coleman AE, et al. Among authors: ruple a. Geroscience. 2025 Feb 14. doi: 10.1007/s11357-024-01484-7. Online ahead of print. Geroscience. 2025. PMID: 39951177 Review.
An open science study of ageing in companion dogs.
Creevy KE, Akey JM, Kaeberlein M, Promislow DEL; Dog Aging Project Consortium. Creevy KE, et al. Nature. 2022 Feb;602(7895):51-57. doi: 10.1038/s41586-021-04282-9. Epub 2022 Feb 2. Nature. 2022. PMID: 35110758 Free PMC article.
74 results