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Year Number of Results
2014 3
2015 4
2016 1
2017 3
2018 1
2019 6
2020 2
2021 3
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21 results
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Page 1
TASK Channels Pharmacology: New Challenges in Drug Design.
Bedoya M, Rinné S, Kiper AK, Decher N, González W, Ramírez D. Bedoya M, et al. Among authors: kiper ak. J Med Chem. 2019 Nov 27;62(22):10044-10058. doi: 10.1021/acs.jmedchem.9b00248. Epub 2019 Jul 15. J Med Chem. 2019. PMID: 31260312 Review.
A lower X-gate in TASK channels traps inhibitors within the vestibule.
Rödström KEJ, Kiper AK, Zhang W, Rinné S, Pike ACW, Goldstein M, Conrad LJ, Delbeck M, Hahn MG, Meier H, Platzk M, Quigley A, Speedman D, Shrestha L, Mukhopadhyay SMM, Burgess-Brown NA, Tucker SJ, Müller T, Decher N, Carpenter EP. Rödström KEJ, et al. Among authors: kiper ak. Nature. 2020 Jun;582(7812):443-447. doi: 10.1038/s41586-020-2250-8. Epub 2020 Apr 29. Nature. 2020. PMID: 32499642
Molecular Pharmacology of K2P Potassium Channels.
Decher N, Rinné S, Bedoya M, Gonzalez W, Kiper AK. Decher N, et al. Among authors: kiper ak. Cell Physiol Biochem. 2021 Mar 6;55(S3):87-107. doi: 10.33594/000000339. Cell Physiol Biochem. 2021. PMID: 33667333 Free article. Review.
The VAMP-associated protein VAPB is required for cardiac and neuronal pacemaker channel function.
Silbernagel N, Walecki M, Schäfer MK, Kessler M, Zobeiri M, Rinné S, Kiper AK, Komadowski MA, Vowinkel KS, Wemhöner K, Fortmüller L, Schewe M, Dolga AM, Scekic-Zahirovic J, Matschke LA, Culmsee C, Baukrowitz T, Monassier L, Ullrich ND, Dupuis L, Just S, Budde T, Fabritz L, Decher N. Silbernagel N, et al. Among authors: kiper ak. FASEB J. 2018 Nov;32(11):6159-6173. doi: 10.1096/fj.201800246R. Epub 2018 Jun 7. FASEB J. 2018. PMID: 29879376 Free PMC article.
POPDC2 a novel susceptibility gene for conduction disorders.
Rinné S, Ortiz-Bonnin B, Stallmeyer B, Kiper AK, Fortmüller L, Schindler RFR, Herbort-Brand U, Kabir NS, Dittmann S, Friedrich C, Zumhagen S, Gualandi F, Selvatici R, Rapezzi C, Arbustini E, Ferlini A, Fabritz L, Schulze-Bahr E, Brand T, Decher N. Rinné S, et al. Among authors: kiper ak. J Mol Cell Cardiol. 2020 Aug;145:74-83. doi: 10.1016/j.yjmcc.2020.06.005. Epub 2020 Jun 11. J Mol Cell Cardiol. 2020. PMID: 32535041
A pharmacological master key mechanism that unlocks the selectivity filter gate in K+ channels.
Schewe M, Sun H, Mert Ü, Mackenzie A, Pike ACW, Schulz F, Constantin C, Vowinkel KS, Conrad LJ, Kiper AK, Gonzalez W, Musinszki M, Tegtmeier M, Pryde DC, Belabed H, Nazare M, de Groot BL, Decher N, Fakler B, Carpenter EP, Tucker SJ, Baukrowitz T. Schewe M, et al. Among authors: kiper ak. Science. 2019 Feb 22;363(6429):875-880. doi: 10.1126/science.aav0569. Science. 2019. PMID: 30792303 Free PMC article.
Stress-Kinase Regulation of TASK-1 and TASK-3.
Rinné S, Kiper AK, Schmidt C, Ortiz-Bonnin B, Zwiener S, Seebohm G, Decher N. Rinné S, et al. Among authors: kiper ak. Cell Physiol Biochem. 2017;44(3):1024-1037. doi: 10.1159/000485402. Epub 2017 Nov 27. Cell Physiol Biochem. 2017. PMID: 29179200 Free article.
21 results