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Discovery of a novel 2,5-dihydroxycinnamic acid-based 5-lipoxygenase inhibitor that induces apoptosis and may impair autophagic flux in RCC4 renal cancer cells.
Selka A, Doiron JA, Lyons P, Dastous S, Chiasson A, Cormier M, Turcotte S, Surette ME, Touaibia M. Selka A, et al. Eur J Med Chem. 2019 Oct 1;179:347-357. doi: 10.1016/j.ejmech.2019.06.060. Epub 2019 Jun 23. Eur J Med Chem. 2019. PMID: 31260889
Phenolic acid phenethylesters and their corresponding ketones: Inhibition of 5-lipoxygenase and stability in human blood and HepaRG cells.
Mbarik M, Poirier SJ, Doiron J, Selka A, Barnett DA, Cormier M, Touaibia M, Surette ME. Mbarik M, et al. Among authors: selka a. Pharmacol Res Perspect. 2019 Sep 13;7(5):e00524. doi: 10.1002/prp2.524. eCollection 2019 Oct. Pharmacol Res Perspect. 2019. PMID: 31523435 Free PMC article.