Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1967 1
1975 1
1978 2
1983 1
1985 1
1986 1
1990 2
1993 2
1995 1
1996 2
1998 4
1999 3
2000 7
2001 4
2002 11
2003 11
2004 10
2005 16
2006 12
2007 20
2008 20
2009 31
2010 21
2011 28
2012 33
2013 38
2014 45
2015 38
2016 54
2017 47
2018 43
2019 47
2020 57
2021 60
2022 43
2023 53
2024 47
2025 24

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

739 results

Results by year

Filters applied: . Clear all
Page 1
Characterisation and Immunogenicity of Neisseria cinerea outer membrane vesicles displaying NadA, NHBA and fHbp from Neisseria meningitidis serogroup B.
Manoharan S, Farman TA, Piliou S, Mastroeni P. Manoharan S, et al. Front Immunol. 2024 Sep 24;15:1473064. doi: 10.3389/fimmu.2024.1473064. eCollection 2024. Front Immunol. 2024. PMID: 39380985 Free PMC article.
More affordable and effective vaccines against bacterial meningitis caused by Neisseria meningitidis serogroup B are still required for global prevention. We have previously shown that modified outer membrane vesicles (mOMVs) from commensal Neisseria cinerea can be used as …
More affordable and effective vaccines against bacterial meningitis caused by Neisseria meningitidis serogroup B are still required f …
Neisserial adhesin A (NadA) binds human Siglec-5 and Siglec-14 with high affinity and promotes bacterial adhesion/invasion.
Benucci B, Spinello Z, Calvaresi V, Viviani V, Perrotta A, Faleri A, Utrio Lanfaloni S, Pansegrau W, d'Alterio L, Bartolini E, Pinzuti I, Sampieri K, Giordano A, Rappuoli R, Pizza M, Masignani V, Norais N, Maione D, Merola M. Benucci B, et al. mBio. 2024 Aug 14;15(8):e0110724. doi: 10.1128/mbio.01107-24. Epub 2024 Jul 23. mBio. 2024. PMID: 39041817 Free PMC article.
Neisserial adhesin A (NadA) is a meningococcal surface protein included as recombinant antigen in 4CMenB, a protein-based vaccine able to induce protective immune responses against Neisseria meningitidis serogroup B (MenB). ...Knowledge of the host and pathogen fact …
Neisserial adhesin A (NadA) is a meningococcal surface protein included as recombinant antigen in 4CMenB, a protein-based vaccine abl …
Product review on the IMD serogroup B vaccine Bexsero.
Deghmane AE, Taha MK. Deghmane AE, et al. Hum Vaccin Immunother. 2022 Dec 31;18(1):2020043. doi: 10.1080/21645515.2021.2020043. Epub 2022 Feb 22. Hum Vaccin Immunother. 2022. PMID: 35192786 Free PMC article.
Bexsero is a multicomponent vaccine composed of four major proteins of Neisseria meningitidis: the fHbp, NHBA, NadA and PorA. This vaccine was licensed against invasive meningococcal disease (IMD) due to serogroup B isolates. ...Although the vaccine does not seem to …
Bexsero is a multicomponent vaccine composed of four major proteins of Neisseria meningitidis: the fHbp, NHBA, NadA and PorA. This va …
Csk restrains BCR-mediated ROS production and contributes to germinal center selection and affinity maturation.
Inoue T, Matsumoto Y, Kawai C, Ito M, Nada S, Okada M, Kurosaki T. Inoue T, et al. J Exp Med. 2024 Jul 1;221(7):e20231996. doi: 10.1084/jem.20231996. Epub 2024 May 16. J Exp Med. 2024. PMID: 38753246 Free PMC article.
Compared with naive B cells, the B cell receptor (BCR) signal in germinal center (GC) B cells is attenuated; however, the significance of this signaling attenuation has not been well defined. ...Mechanistically, ROS-induced apoptosis was exacerbated concomita …
Compared with naive B cells, the B cell receptor (BCR) signal in germinal center (GC) B cells is attenuated; however, t …
Meningococcal B Immunisation in Adults and Potential Broader Immunisation Strategies: A Narrative Review.
Kassianos G, Barasheed O, Abbing-Karahagopian V, Khalaf M, Ozturk S, Banzhoff A, Badur S. Kassianos G, et al. Infect Dis Ther. 2023 Sep;12(9):2193-2219. doi: 10.1007/s40121-023-00836-8. Epub 2023 Jul 6. Infect Dis Ther. 2023. PMID: 37428339 Free PMC article. Review.
Recombinant vaccines against invasive meningococcal disease due to Neisseria meningitidis serogroup B (MenB) have shown substantial impact in reducing MenB disease in targeted populations. 4CMenB targets four key N. meningitidis protein antigens; human factor H binding pro …
Recombinant vaccines against invasive meningococcal disease due to Neisseria meningitidis serogroup B (MenB) have shown substantial i …
Transcriptional regulation of the nadA gene in Neisseria meningitidis impacts the prediction of coverage of a multicomponent meningococcal serogroup B vaccine.
Fagnocchi L, Biolchi A, Ferlicca F, Boccadifuoco G, Brunelli B, Brier S, Norais N, Chiarot E, Bensi G, Kroll JS, Pizza M, Donnelly J, Giuliani MM, Delany I. Fagnocchi L, et al. Infect Immun. 2013 Feb;81(2):560-9. doi: 10.1128/IAI.01085-12. Epub 2012 Dec 10. Infect Immun. 2013. PMID: 23230289 Free PMC article.
The NadA adhesin is a major component of 4CMenB, a novel vaccine to prevent meningococcus serogroup B (MenB) infection. ...Our results suggest that during infectious disease, NadR repression is alleviated due to niche-specific signals, resulting in high levels of …
The NadA adhesin is a major component of 4CMenB, a novel vaccine to prevent meningococcus serogroup B (MenB) infection. ...Our …
Characterization of fHbp, nhba (gna2132), nadA, porA, and sequence type in group B meningococcal case isolates collected in England and Wales during January 2008 and potential coverage of an investigational group B meningococcal vaccine.
Lucidarme J, Comanducci M, Findlow J, Gray SJ, Kaczmarski EB, Guiver M, Vallely PJ, Oster P, Pizza M, Bambini S, Muzzi A, Borrow R. Lucidarme J, et al. Clin Vaccine Immunol. 2010 Jun;17(6):919-29. doi: 10.1128/CVI.00027-10. Epub 2010 Apr 7. Clin Vaccine Immunol. 2010. PMID: 20375242 Free PMC article.
In an alternative approach, the first-generation, investigational, recombinant MenB (rMenB) plus outer membrane vesicle (OMV) (rMenB-OMV) vaccine contains a number of relatively conserved surface proteins, fHBP, NHBA (previously GNA2132), and NadA, alongside PorA P1.4-cont …
In an alternative approach, the first-generation, investigational, recombinant MenB (rMenB) plus outer membrane vesicle (OMV) (rMenB-OMV) va …
Children with perinatally acquired HIV exhibit distinct immune responses to 4CMenB vaccine.
Cotugno N, Neri A, Sanna M, Santilli V, Manno EC, Pascucci GR, Morrocchi E, Amodio D, Ruggiero A, Ciofi Degl Atti ML, Barneschi I, Grappi S, Cocchi I, Giacomet V, Trabattoni D, Olivieri G, Bernardi S, O'Connor D, Montomoli E, Pollard AJ, Palma P. Cotugno N, et al. JCI Insight. 2024 Apr 11;9(10):e177182. doi: 10.1172/jci.insight.177182. JCI Insight. 2024. PMID: 38775152 Free PMC article.
Assessments included the standard human serum bactericidal antibody (hSBA) assay and measurement of IgG titers against capsular group B Neisseria meningitidis antigens (fHbp, NHBA, NadA). The B cell compartment and vaccine-induced antigen-specific (fHbp+) …
Assessments included the standard human serum bactericidal antibody (hSBA) assay and measurement of IgG titers against capsular group B …
Solanoeclepin B, a hatching factor for potato cyst nematode.
Shimizu K, Akiyama R, Okamura Y, Ogawa C, Masuda Y, Sakata I, Watanabe B, Sugimoto Y, Kushida A, Tanino K, Mizutani M. Shimizu K, et al. Sci Adv. 2023 Mar 17;9(11):eadf4166. doi: 10.1126/sciadv.adf4166. Epub 2023 Mar 15. Sci Adv. 2023. PMID: 36921046 Free PMC article.
Solanoeclepin A (SEA), isolated from potato, is the most active HF for PCN; however, its biosynthesis is completely unknown. We discovered a HF called solanoeclepin B (SEB) from potato and tomato root exudates and showed that SEB was biosynthesized in the plant and convert …
Solanoeclepin A (SEA), isolated from potato, is the most active HF for PCN; however, its biosynthesis is completely unknown. We discovered a …
The soluble recombinant Neisseria meningitidis adhesin NadA(delta351-405) stimulates human monocytes by binding to extracellular Hsp90.
Cecchini P, Tavano R, Polverino de Laureto P, Franzoso S, Mazzon C, Montanari P, Papini E. Cecchini P, et al. PLoS One. 2011;6(9):e25089. doi: 10.1371/journal.pone.0025089. Epub 2011 Sep 16. PLoS One. 2011. PMID: 21949862 Free PMC article.
The adhesin NadA favors cell adhesion/invasion by hypervirulent Neisseria meningitidis B (MenB). Its recombinant form NadA(delta351-405,) devoid of the outer membrane domain, is an immunogenic candidate for an anti-MenB vaccine able to stimulate monocytes, ma …
The adhesin NadA favors cell adhesion/invasion by hypervirulent Neisseria meningitidis B (MenB). Its recombinant form NadA …
739 results