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The following term was not found in PubMed: Rivza
Page 1
β-aminoisobutyric acid attenuates LPS-induced inflammation and insulin resistance in adipocytes through AMPK-mediated pathway.
Jung TW, Park HS, Choi GH, Kim D, Lee T. Jung TW, et al. J Biomed Sci. 2018 Mar 28;25(1):27. doi: 10.1186/s12929-018-0431-7. J Biomed Sci. 2018. PMID: 29592806 Free PMC article.
Previous reports have also demonstrated strong anti-inflammatory effects of BAIBA. METHODS: We used BAIBA treated fully differentiated 3T3T-L1 mouse adipocytes to investigate the effects of exogenous BAIBA on inflammation and insulin signaling in adipocytes. …
Previous reports have also demonstrated strong anti-inflammatory effects of BAIBA. METHODS: We used BAIBA treated fully differ …
Regulation of Skeletal Muscle Function by Amino Acids.
Kamei Y, Hatazawa Y, Uchitomi R, Yoshimura R, Miura S. Kamei Y, et al. Nutrients. 2020 Jan 19;12(1):261. doi: 10.3390/nu12010261. Nutrients. 2020. PMID: 31963899 Free PMC article. Review.
The metabolite of valine (another BCAA), beta-aminoisobutyric acid (BAIBA), is increased by exercise, is secreted by the skeletal muscle, and acts on other tissues, such as white adipose tissue, to increase energy expenditure. ...
The metabolite of valine (another BCAA), beta-aminoisobutyric acid (BAIBA), is increased by exercise, is secreted by the skeletal mus …
Both enantiomers of beta-aminoisobutyric acid BAIBA regulate Fgf23 via MRGPRD receptor by activating distinct signaling pathways in osteocytes.
Sakamoto E, Kitase Y, Fitt AJ, Zhu Z, Awad K, Brotto M, White KE, Welc SS, Bergwitz C, Bonewald LF. Sakamoto E, et al. Cell Rep. 2024 Jul 23;43(7):114397. doi: 10.1016/j.celrep.2024.114397. Epub 2024 Jun 25. Cell Rep. 2024. PMID: 38935499 Free PMC article.
Exercise in mice increased fibroblast growth factor 23 (FGF23), urine phosphate, and the muscle metabolite L-beta-aminoisobutyric acid (L-BAIBA), suggesting that L-BAIBA may play a role in phosphate metabolism. Here, we show that L-BAIBA increases in serum wi …
Exercise in mice increased fibroblast growth factor 23 (FGF23), urine phosphate, and the muscle metabolite L-beta-aminoisobutyric acid (L- …
The Role of Exercise in the Interplay between Myokines, Hepatokines, Osteokines, Adipokines, and Modulation of Inflammation for Energy Substrate Redistribution and Fat Mass Loss: A Review.
Gonzalez-Gil AM, Elizondo-Montemayor L. Gonzalez-Gil AM, et al. Nutrients. 2020 Jun 26;12(6):1899. doi: 10.3390/nu12061899. Nutrients. 2020. PMID: 32604889 Free PMC article. Review.
In this review, we explain the potential role of these exercise-inducible factors, namely myokines, such as irisin, IL-6, IL-15, METRNL, BAIBA, and myostatin, and hepatokines, in particular selenoprotein P, fetuin A, FGF21, ANGPTL4, and follistatin. ...
In this review, we explain the potential role of these exercise-inducible factors, namely myokines, such as irisin, IL-6, IL-15, METRNL, …
The muscle-intervertebral disc interaction mediated by L-BAIBA modulates extracellular matrix homeostasis and PANoptosis in nucleus pulposus cells.
Qin T, Shi M, Zhang C, Wu J, Huang Z, Zhang X, Li S, Wu Y, Han W, Gao B, Xu K, Jin S, Ye W. Qin T, et al. Exp Mol Med. 2024 Nov;56(11):2503-2518. doi: 10.1038/s12276-024-01345-5. Epub 2024 Nov 7. Exp Mol Med. 2024. PMID: 39511429 Free PMC article.
Our study demonstrated that exercise significantly elevates BAIBA levels in skeletal muscle, plasma, and nucleus pulposus (NP) tissues. Moreover, exercise enhances extracellular matrix (ECM) synthesis in NP tissues and upregulates L-BAIBA synthase in skeletal muscle …
Our study demonstrated that exercise significantly elevates BAIBA levels in skeletal muscle, plasma, and nucleus pulposus (NP) tissue …
Bone-Muscle Mutual Interactions.
Lara-Castillo N, Johnson ML. Lara-Castillo N, et al. Curr Osteoporos Rep. 2020 Aug;18(4):408-421. doi: 10.1007/s11914-020-00602-6. Curr Osteoporos Rep. 2020. PMID: 32519283 Free PMC article. Review.
These include muscle factors such as myostatin, Irisin, BAIBA, IL-6, and the IGF family and the bone factors FGF-23, Wnt1 and Wnt3a, PGE2, FGF9, RANKL, osteocalcin, and sclerostin. ...
These include muscle factors such as myostatin, Irisin, BAIBA, IL-6, and the IGF family and the bone factors FGF-23, Wnt1 and Wnt3a, …
β-aminoisobutyrics acid, a metabolite of BCAA, activates the AMPK/Nrf-2 pathway to prevent ferroptosis and ameliorates lung ischemia-reperfusion injury.
Zhang Z, Li X, Guo J, He B, Wu L, Yang R, Li X, Fang D, Yang X, Yang D, Wang F, Tang M, Han Y, Jose PA, Wang H, Zeng C. Zhang Z, et al. Mol Med. 2023 Dec 4;29(1):164. doi: 10.1186/s10020-023-00729-z. Mol Med. 2023. PMID: 38049750 Free PMC article.
Additionally, we demonstrated that the Nrf-2 signaling pathway is key to the inhibitory effect of L-BAIBA on ferroptosis in A549 and BEAS-2B cells. L-BAIBA can induce the nuclear translocation of Nrf-2. Interfering with the expression of Nrf-2 eliminated the protect …
Additionally, we demonstrated that the Nrf-2 signaling pathway is key to the inhibitory effect of L-BAIBA on ferroptosis in A549 and …
A Novel Gliotransmitter, L-β-Aminoisobutyric Acid, Contributes to Pathophysiology of Clinical Efficacies and Adverse Reactions of Clozapine.
Fukuyama K, Motomura E, Okada M. Fukuyama K, et al. Biomolecules. 2023 Aug 23;13(9):1288. doi: 10.3390/biom13091288. Biomolecules. 2023. PMID: 37759688 Free PMC article. Review.
Recently, the GABA isomer L-beta-aminoisobutyric acid (L-BAIBA), a protective myokine in the peripheral organs, was identified as a candidate novel transmission modulator in the central nervous system (CNS). L-BAIBA activates adenosine monophosphate-activated protei …
Recently, the GABA isomer L-beta-aminoisobutyric acid (L-BAIBA), a protective myokine in the peripheral organs, was identified as a c …
An Overview of the Molecular Mechanisms Contributing to Musculoskeletal Disorders in Chronic Liver Disease: Osteoporosis, Sarcopenia, and Osteoporotic Sarcopenia.
Yang YJ, Kim DJ. Yang YJ, et al. Int J Mol Sci. 2021 Mar 5;22(5):2604. doi: 10.3390/ijms22052604. Int J Mol Sci. 2021. PMID: 33807573 Free PMC article. Review.
The bidirectional crosstalk between muscle and bone through myostatin, irisin, beta-aminoisobutyric acid (BAIBA), osteocalcin, as well as the activation of the RANK and the Wnt/beta-catenin pathways are associated with osteosarcopenia. ...
The bidirectional crosstalk between muscle and bone through myostatin, irisin, beta-aminoisobutyric acid (BAIBA), osteocalcin, as wel …
137 results