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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1965 10
1966 8
1967 5
1968 10
1969 11
1970 7
1971 6
1972 12
1973 7
1974 10
1975 6
1976 3
1977 7
1978 8
1979 6
1980 9
1981 15
1982 7
1983 7
1984 12
1985 7
1986 10
1987 8
1988 12
1989 13
1990 10
1991 10
1992 10
1993 7
1994 13
1995 7
1996 9
1997 10
1998 6
1999 4
2000 6
2001 4
2002 5
2003 4
2004 4
2005 7
2007 2
2008 4
2010 1
2011 4
2012 4
2013 7
2014 5
2015 2
2016 3
2017 4
2018 6
2019 4
2020 9
2021 6
2022 8
2023 9
2024 1

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408 results

Results by year

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Page 1
Small-molecule factor B inhibitor for the treatment of complement-mediated diseases.
Schubart A, Anderson K, Mainolfi N, Sellner H, Ehara T, Adams CM, Mac Sweeney A, Liao SM, Crowley M, Littlewood-Evans A, Sarret S, Wieczorek G, Perrot L, Dubost V, Flandre T, Zhang Y, Smith RJH, Risitano AM, Karki RG, Zhang C, Valeur E, Sirockin F, Gerhartz B, Erbel P, Hughes N, Smith TM, Cumin F, Argikar UA, Haraldsson B, Mogi M, Sedrani R, Wiesmann C, Jaffee B, Maibaum J, Flohr S, Harrison R, Eder J. Schubart A, et al. Proc Natl Acad Sci U S A. 2019 Apr 16;116(16):7926-7931. doi: 10.1073/pnas.1820892116. Epub 2019 Mar 29. Proc Natl Acad Sci U S A. 2019. PMID: 30926668 Free PMC article.
Dysregulation of the alternative complement pathway (AP) predisposes individuals to a number of diseases including paroxysmal nocturnal hemoglobinuria, atypical hemolytic uremic syndrome, and C3 glomerulopathy. Moreover, glomerular Ig deposits can lead to complement-driven …
Dysregulation of the alternative complement pathway (AP) predisposes individuals to a number of diseases including paroxysmal nocturnal hemo …
Probing Colossal Carbon Rings.
Marlton SJP, Buntine JT, Watkins P, Liu C, Jacovella U, Carrascosa E, Bull JN, Bieske EJ. Marlton SJP, et al. J Phys Chem A. 2023 Feb 9;127(5):1168-1178. doi: 10.1021/acs.jpca.2c07068. Epub 2023 Jan 26. J Phys Chem A. 2023. PMID: 36703560
Generally, the observed charged photofragments correspond to low energy fragment pairs, as predicted by density functional theory calculations (CAM-B3LYP-D3(BJ)/cc-pVDZ). Using action spectroscopy it is confirmed that C14+ and C18+ photofragments from C28+ rings have cycli …
Generally, the observed charged photofragments correspond to low energy fragment pairs, as predicted by density functional theory calculatio …
Sulfoquinovose in the biosphere: occurrence, metabolism and functions.
Goddard-Borger ED, Williams SJ. Goddard-Borger ED, et al. Biochem J. 2017 Feb 20;474(5):827-849. doi: 10.1042/BCJ20160508. Biochem J. 2017. PMID: 28219973 Review.
On the other hand, two major sulfoglycolytic pathways have been discovered for SQDG degradation, the sulfo-Embden-Meyerhof-Parnas (sulfo-EMP) and sulfo-Entner-Doudoroff (sulfo-ED) pathways, which mirror the major steps in the glycolytic EMP and ED pathways. Sulfoglycolysis produc …
On the other hand, two major sulfoglycolytic pathways have been discovered for SQDG degradation, the sulfo-Embden-Meyerhof-Parnas (sulfo-EMP …
Biochemical characterization of phosphoenolpyruvate carboxykinases from Arabidopsis thaliana.
Rojas BE, Hartman MD, Figueroa CM, Leaden L, Podestá FE, Iglesias AA. Rojas BE, et al. Biochem J. 2019 Oct 30;476(20):2939-2952. doi: 10.1042/BCJ20190523. Biochem J. 2019. PMID: 31548269
However, our knowledge on the structural, kinetic and regulatory properties of the enzymes from C3 species is still limited. In this work, we report the recombinant production and biochemical characterization of two PEPCKs identified in Arabidopsis thaliana: AthPEPCK1 and …
However, our knowledge on the structural, kinetic and regulatory properties of the enzymes from C3 species is still limited. In this …
Complement-Opsonized NIR-IIb Emissive Immunotracers for Dynamically Monitoring Neutrophils in Inflammation-Related Diseases.
Zhang M, Wang Z, Shao Y, Zhao Y, Liu Z. Zhang M, et al. Adv Mater. 2022 Aug;34(34):e2203477. doi: 10.1002/adma.202203477. Epub 2022 Jul 25. Adv Mater. 2022. PMID: 35793262
Inspired by the natural biological function of the complement system, a strategy of enhancing the complement C3 opsonization of lanthanide-doped nanoparticles (LnNPs) by modulating their surface chemistry, thus developing a near infrared-IIb emissive nanotracer for neutrop …
Inspired by the natural biological function of the complement system, a strategy of enhancing the complement C3 opsonization of lanth …
Biotransformation of Sclareol by a Fungal Endophyte of Salvia sclarea.
Diao M, Li C, Lu J, Meng L, Xie N. Diao M, et al. Chem Biodivers. 2023 Dec;20(12):e202301363. doi: 10.1002/cbdv.202301363. Epub 2023 Nov 15. Chem Biodivers. 2023. PMID: 37899305
A fungal endophyte, identified as the generally recognized as safe (GRAS) strain Aspergillus tubingensis, can produce labd-14-ene-3beta,8alpha,13beta-triol and 8alpha,13beta-dihydroxylabd-14-en-3-one from sclareol, involving hydroxylation and carbonylation at the C3 site. …
A fungal endophyte, identified as the generally recognized as safe (GRAS) strain Aspergillus tubingensis, can produce labd-14-ene-3beta,8alp …
Absolute configuration of dolichol.
Adair WL Jr, Robertson S. Adair WL Jr, et al. Biochem J. 1980 Sep 1;189(3):441-5. doi: 10.1042/bj1890441. Biochem J. 1980. PMID: 7213338 Free PMC article.
New lupane bidesmosides exhibiting strong cytotoxic activities in vitro.
Korda A, Rárová L, Pakulski Z, Strnad M, Oklešťková J, Kuczynska K, Cmoch P, Gwardiak K, Karczewski R. Korda A, et al. Bioorg Chem. 2020 Jul;100:103868. doi: 10.1016/j.bioorg.2020.103868. Epub 2020 Apr 27. Bioorg Chem. 2020. PMID: 32388425 Free article.
Cytotoxicity of all compounds was tested in vitro for a series of cancer cell lines, as well as normal human skin BJ fibroblasts. Presence of l-rhamnose moiety is crucial for cytotoxicity of betulin bidesmosides. ...
Cytotoxicity of all compounds was tested in vitro for a series of cancer cell lines, as well as normal human skin BJ fibroblasts. Pre …
C-X Bond Activation by Palladium: Steric Shielding versus Steric Attraction.
Hansen T, Sun X, Dalla Tiezza M, van Zeist WJ, van Stralen JNP, Geerke DP, Wolters LP, Poater J, Hamlin TA, Bickelhaupt FM. Hansen T, et al. Chemistry. 2022 Aug 4;28(44):e202201093. doi: 10.1002/chem.202201093. Epub 2022 Jun 16. Chemistry. 2022. PMID: 35420229 Free PMC article.
The C-X bond activation (X = H, C) of a series of substituted C(n)-H and C(n)-C(m) bonds with C(n) and C(m) = H(3) C- (methyl, 0), CH(3) H(2) C- (primary, 1), (CH(3) )(2) HC- (secondary, 2), (CH(3) )(3) C- (tertiary, 3) by palladium were investigated using relativistic dispersion …
The C-X bond activation (X = H, C) of a series of substituted C(n)-H and C(n)-C(m) bonds with C(n) and C(m) = H(3) C- (methyl, 0), CH(3) H(2 …
The correlates of neonatal complement component 3 and 4 protein concentrations with a focus on psychiatric and autoimmune disorders.
Borbye-Lorenzen N, Zhu Z, Agerbo E, Albiñana C, Benros ME, Bian B, Børglum AD, Bulik CM, Debost JPG, Grove J, Hougaard DM, McRae AF, Mors O, Mortensen PB, Musliner KL, Nordentoft M, Petersen LV, Privé F, Sidorenko J, Skogstrand K, Werge T, Wray NR, Vilhjálmsson BJ, McGrath JJ. Borbye-Lorenzen N, et al. Cell Genom. 2023 Dec 13;3(12):100457. doi: 10.1016/j.xgen.2023.100457. eCollection 2023 Dec 13. Cell Genom. 2023. PMID: 38116117 Free PMC article.
The GWASs for C3 and C4 protein concentrations identified 15 and 36 independent loci, respectively. We found no associations between neonatal C3 and C4 concentrations and mental disorders in the total sample (both sexes combined); however, post-hoc analyses found th …
The GWASs for C3 and C4 protein concentrations identified 15 and 36 independent loci, respectively. We found no associations between …
408 results