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Year Number of Results
2013 1
2014 4
2018 1
2019 3
2020 5
2021 2
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Page 1
Discovery, Function, and Therapeutic Targeting of Siglec-8.
Youngblood BA, Leung J, Falahati R, Williams J, Schanin J, Brock EC, Singh B, Chang AT, O'Sullivan JA, Schleimer RP, Tomasevic N, Bebbington CR, Bochner BS. Youngblood BA, et al. Cells. 2020 Dec 24;10(1):19. doi: 10.3390/cells10010019. Cells. 2020. PMID: 33374255 Free PMC article. Review.
AK002, a Humanized Sialic Acid-Binding Immunoglobulin-Like Lectin-8 Antibody that Induces Antibody-Dependent Cell-Mediated Cytotoxicity against Human Eosinophils and Inhibits Mast Cell-Mediated Anaphylaxis in Mice.
Youngblood BA, Brock EC, Leung J, Falahati R, Bryce PJ, Bright J, Williams J, Shultz LD, Greiner DL, Brehm MA, Bebbington C, Tomasevic N. Youngblood BA, et al. Int Arch Allergy Immunol. 2019;180(2):91-102. doi: 10.1159/000501637. Epub 2019 Aug 9. Int Arch Allergy Immunol. 2019. PMID: 31401630 Free PMC article.
Eosinophil and mast cell Siglecs: From biology to drug target.
O'Sullivan JA, Chang AT, Youngblood BA, Bochner BS. O'Sullivan JA, et al. Among authors: youngblood ba. J Leukoc Biol. 2020 Jul;108(1):73-81. doi: 10.1002/JLB.2MR0120-352RR. Epub 2020 Jan 22. J Leukoc Biol. 2020. PMID: 31965606 Review.
A monoclonal antibody to Siglec-8 suppresses non-allergic airway inflammation and inhibits IgE-independent mast cell activation.
Schanin J, Gebremeskel S, Korver W, Falahati R, Butuci M, Haw TJ, Nair PM, Liu G, Hansbro NG, Hansbro PM, Evensen E, Brock EC, Xu A, Wong A, Leung J, Bebbington C, Tomasevic N, Youngblood BA. Schanin J, et al. Among authors: youngblood ba. Mucosal Immunol. 2021 Mar;14(2):366-376. doi: 10.1038/s41385-020-00336-9. Epub 2020 Aug 19. Mucosal Immunol. 2021. PMID: 32814824 Free PMC article.
Sialic acid-binding immunoglobulin-like lectin (Siglec) 8 in patients with eosinophilic disorders: Receptor expression and targeting using chimeric antibodies.
Legrand F, Cao Y, Wechsler JB, Zhu X, Zimmermann N, Rampertaap S, Monsale J, Romito K, Youngblood BA, Brock EC, Makiya MA, Tomasevic N, Bebbington C, Maric I, Metcalfe DD, Bochner BS, Klion AD. Legrand F, et al. Among authors: youngblood ba. J Allergy Clin Immunol. 2019 Jun;143(6):2227-2237.e10. doi: 10.1016/j.jaci.2018.10.066. Epub 2018 Dec 10. J Allergy Clin Immunol. 2019. PMID: 30543818 Free PMC article.
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