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Page 1
Molecular modeling.
Broughton HB. Broughton HB. Curr Opin Chem Biol. 1997 Oct;1(3):392-8. doi: 10.1016/s1367-5931(97)80079-8. Curr Opin Chem Biol. 1997. PMID: 9667875 Review.
Structure and mechanism of inositol monophosphatase.
Atack JR, Broughton HB, Pollack SJ. Atack JR, et al. Among authors: broughton hb. FEBS Lett. 1995 Mar 13;361(1):1-7. doi: 10.1016/0014-5793(95)00063-f. FEBS Lett. 1995. PMID: 7890024 Free article. Review.
New selective cytotoxic diterpenylquinones and diterpenylhydroquinones.
Miguel Del Corral JM, Gordaliza M, Castro MA, Mahiques MM, Chamorro P, Molinari A, García-Grávalos MD, Broughton HB, San Feliciano A. Miguel Del Corral JM, et al. Among authors: broughton hb. J Med Chem. 2001 Apr 12;44(8):1257-67. doi: 10.1021/jm001048q. J Med Chem. 2001. PMID: 11312925
The chemical basis of serine palmitoyltransferase inhibition by myriocin.
Wadsworth JM, Clarke DJ, McMahon SA, Lowther JP, Beattie AE, Langridge-Smith PR, Broughton HB, Dunn TM, Naismith JH, Campopiano DJ. Wadsworth JM, et al. Among authors: broughton hb. J Am Chem Soc. 2013 Sep 25;135(38):14276-85. doi: 10.1021/ja4059876. Epub 2013 Sep 11. J Am Chem Soc. 2013. PMID: 23957439 Free article.
The synthesis of azadirachtin: a potent insect antifeedant.
Ley SV, Abad-Somovilla A, Anderson JC, Ayats C, Bänteli R, Beckmann E, Boyer A, Brasca MG, Brice A, Broughton HB, Burke BJ, Cleator E, Craig D, Denholm AA, Denton RM, Durand-Reville T, Gobbi LB, Göbel M, Gray BL, Grossmann RB, Gutteridge CE, Hahn N, Harding SL, Jennens DC, Jennens L, Lovell PJ, Lovell HJ, de la Puente ML, Kolb HC, Koot WJ, Maslen SL, McCusker CF, Mattes A, Pape AR, Pinto A, Santafianos D, Scott JS, Smith SC, Somers AQ, Spilling CD, Stelzer F, Toogood PL, Turner RM, Veitch GE, Wood A, Zumbrunn C. Ley SV, et al. Among authors: broughton hb. Chemistry. 2008;14(34):10683-704. doi: 10.1002/chem.200801103. Chemistry. 2008. PMID: 18821532
Defining Target Engagement Required for Efficacy In Vivo at the Retinoic Acid Receptor-Related Orphan Receptor C2 (RORγt).
Lugar CW, Clarke CA, Morphy R, Rudyk H, Sapmaz S, Stites RE, Vaught GM, Furness K, Broughton HB, Durst GL, Clawson DK, Stout SL, Guo SY, Durbin JD, Stayrook KR, Edmondson DD, Kikly K, New NE, Bina HA, Chambers MG, Shetler P, Chang WY, Chang VC, Barr R, Gough WH, Steele JP, Getman B, Patel N, Mathes BM, Richardson TI. Lugar CW, et al. Among authors: broughton hb. J Med Chem. 2021 May 13;64(9):5470-5484. doi: 10.1021/acs.jmedchem.0c01918. Epub 2021 Apr 14. J Med Chem. 2021. PMID: 33852312
31 results