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Avadomide monotherapy in relapsed/refractory DLBCL: safety, efficacy, and a predictive gene classifier.

Carpio C, Bouabdallah R, Ysebaert L, Sancho JM, Salles G, Cordoba R, Pinto A, Gharibo M, Rasco D, Panizo C, Lopez-Martin JA, Santoro A, Salar A, Damian S, Martin A, Verhoef G, Van den Neste E, Wang M, Couto S, Carrancio S, Weng A, Wang X, Schmitz F, Wei X, Hege K, Trotter MWB, Risueño A, Buchholz TJ, Hagner PR, Gandhi AK, Pourdehnad M, Ribrag V. Carpio C, et al. Among authors: buchholz tj. Blood. 2020 Mar 26;135(13):996-1007. doi: 10.1182/blood.2019002395. Blood. 2020. PMID: 31977002 Free PMC article.

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Immunoproteasome functions explained by divergence in cleavage specificity and regulation.

Winter MB, La Greca F, Arastu-Kapur S, Caiazza F, Cimermancic P, Buchholz TJ, Anderl JL, Ravalin M, Bohn MF, Sali A, O'Donoghue AJ, Craik CS. Winter MB, et al. Among authors: buchholz tj. Elife. 2017 Nov 28;6:e27364. doi: 10.7554/eLife.27364. Elife. 2017. PMID: 29182146 Free PMC article.

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Paradoxical resistance of multiple myeloma to proteasome inhibitors by decreased levels of 19S proteasomal subunits.

Acosta-Alvear D, Cho MY, Wild T, Buchholz TJ, Lerner AG, Simakova O, Hahn J, Korde N, Landgren O, Maric I, Choudhary C, Walter P, Weissman JS, Kampmann M. Acosta-Alvear D, et al. Among authors: buchholz tj. Elife. 2015 Sep 1;4:e08153. doi: 10.7554/eLife.08153. Elife. 2015. PMID: 26327694 Free PMC article.

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Development of a capillary electrophoresis platform for identifying inhibitors of protein-protein interactions.

Rauch JN, Nie J, Buchholz TJ, Gestwicki JE, Kennedy RT. Rauch JN, et al. Among authors: buchholz tj. Anal Chem. 2013 Oct 15;85(20):9824-31. doi: 10.1021/ac4023082. Epub 2013 Sep 23. Anal Chem. 2013. PMID: 24060167 Free PMC article.

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Structural basis for binding specificity between subclasses of modular polyketide synthase docking domains.

Buchholz TJ, Geders TW, Bartley FE 3rd, Reynolds KA, Smith JL, Sherman DH. Buchholz TJ, et al. ACS Chem Biol. 2009 Jan 16;4(1):41-52. doi: 10.1021/cb8002607. ACS Chem Biol. 2009. PMID: 19146481 Free PMC article.

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The immunoproteasome β5i subunit is a key contributor to ictogenesis in a rat model of chronic epilepsy.

Mishto M, Raza ML, de Biase D, Ravizza T, Vasuri F, Martucci M, Keller C, Bellavista E, Buchholz TJ, Kloetzel PM, Pession A, Vezzani A, Heinemann U. Mishto M, et al. Among authors: buchholz tj. Brain Behav Immun. 2015 Oct;49:188-96. doi: 10.1016/j.bbi.2015.05.007. Epub 2015 Jun 1. Brain Behav Immun. 2015. PMID: 26044087

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Polyketide β-branching in bryostatin biosynthesis: identification of surrogate acetyl-ACP donors for BryR, an HMG-ACP synthase.

Buchholz TJ, Rath CM, Lopanik NB, Gardner NP, Håkansson K, Sherman DH. Buchholz TJ, et al. Chem Biol. 2010 Oct 29;17(10):1092-100. doi: 10.1016/j.chembiol.2010.08.008. Chem Biol. 2010. PMID: 21035732 Free PMC article.

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Substrate profile analysis and ACP-mediated acyl transfer in Streptomyces coelicolor Type III polyketide synthases.

Grüschow S, Buchholz TJ, Seufert W, Dordick JS, Sherman DH. Grüschow S, et al. Among authors: buchholz tj. Chembiochem. 2007 May 25;8(8):863-8. doi: 10.1002/cbic.200700026. Chembiochem. 2007. PMID: 17440908 Free article. No abstract available.

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In vivo and in vitro trans-acylation by BryP, the putative bryostatin pathway acyltransferase derived from an uncultured marine symbiont.

Lopanik NB, Shields JA, Buchholz TJ, Rath CM, Hothersall J, Haygood MG, Håkansson K, Thomas CM, Sherman DH. Lopanik NB, et al. Among authors: buchholz tj. Chem Biol. 2008 Nov 24;15(11):1175-86. doi: 10.1016/j.chembiol.2008.09.013. Chem Biol. 2008. PMID: 19022178 Free PMC article.

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Antitumor activity of PR-171, a novel irreversible inhibitor of the proteasome.

Demo SD, Kirk CJ, Aujay MA, Buchholz TJ, Dajee M, Ho MN, Jiang J, Laidig GJ, Lewis ER, Parlati F, Shenk KD, Smyth MS, Sun CM, Vallone MK, Woo TM, Molineaux CJ, Bennett MK. Demo SD, et al. Among authors: buchholz tj. Cancer Res. 2007 Jul 1;67(13):6383-91. doi: 10.1158/0008-5472.CAN-06-4086. Cancer Res. 2007. PMID: 17616698 Free article.

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