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1983 5
1984 3
1985 1
1986 1
1987 1
1988 1
1989 2
1990 2
1991 1
1992 4
1993 1
1998 2
2000 3
2002 2
2003 2
2004 4
2005 1
2006 1
2007 1
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2024 0

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91 results

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Page 1
Complement's hidden arsenal: New insights and novel functions inside the cell.
Liszewski MK, Elvington M, Kulkarni HS, Atkinson JP. Liszewski MK, et al. Mol Immunol. 2017 Apr;84:2-9. doi: 10.1016/j.molimm.2017.01.004. Epub 2017 Feb 10. Mol Immunol. 2017. PMID: 28196665 Free PMC article. Review.
We now know that a) C3 serves as a damage-associated molecular pattern (in particular by coating pathogens that translocate into cells), b) most cells store C3 and recycle C3(H(2)O) for immediate use, and c) C3 assists in cellular survival and metabolic reprogrammin …
We now know that a) C3 serves as a damage-associated molecular pattern (in particular by coating pathogens that translocate into cells), b) …
Isotopic equifinality and rethinking the diet of Australopithecus anamensis.
Quinn RL. Quinn RL. Am J Phys Anthropol. 2019 Jul;169(3):403-421. doi: 10.1002/ajpa.23846. Epub 2019 May 3. Am J Phys Anthropol. 2019. PMID: 31049941
Here I test the hypothesis that changing the variables (epsilon(*)(enamel-diet) , delta(13) C(C3,) delta(13) C(C4) values) used to calculate the percentage of dietary C(4) foods (%C(4) diet) by 1-2 does not make a substantial difference for hominin diet reconstructi …
Here I test the hypothesis that changing the variables (epsilon(*)(enamel-diet) , delta(13) C(C3,) delta(13) C(C4) values) use …
Inhibition of macrophage migration by C. botulinum exoenzyme C3.
Rotsch J, Rohrbeck A, May M, Kolbe T, Hagemann S, Schelle I, Just I, Genth H, Huelsenbeck SC. Rotsch J, et al. Naunyn Schmiedebergs Arch Pharmacol. 2012 Sep;385(9):883-90. doi: 10.1007/s00210-012-0764-9. Epub 2012 May 29. Naunyn Schmiedebergs Arch Pharmacol. 2012. PMID: 22644106
C3bot is the prototype of C3-like exoenzymes that specifically ADP-ribosylates and thereby inactivates Rho(A/B/C). C3-like exoenzymes are not yet regarded as virulence factors, as the lack of cell entry domains results in a poor accessibility of the C3-like exoenzym …
C3bot is the prototype of C3-like exoenzymes that specifically ADP-ribosylates and thereby inactivates Rho(A/B/C). C3-like exo …
Structural characterization of the C3 domain of cardiac myosin binding protein C and its hypertrophic cardiomyopathy-related R502W mutant.
Zhang XL, De S, McIntosh LP, Paetzel M. Zhang XL, et al. Biochemistry. 2014 Aug 19;53(32):5332-42. doi: 10.1021/bi500784g. Epub 2014 Aug 7. Biochemistry. 2014. PMID: 25058872
Here we present the nuclear magnetic resonance-derived structural ensembles of the wild-type cMyBP-C C3 domain and its HCM-related R502W mutant. The C3 domain adopts an immunoglobulin-like fold, and mutation of the exposed Arg502 to a tryptophan does not perturb its …
Here we present the nuclear magnetic resonance-derived structural ensembles of the wild-type cMyBP-C C3 domain and its HCM-rel …
Honokiol inhibits the growth of SKBR3 cells.
Shi H, Wang Y, Yao M, Zhang D, Fang W, Zhou T, Gan D, Yue S, Qian H, Chen T. Shi H, et al. Transl Cancer Res. 2020 Dec;9(12):7596-7604. doi: 10.21037/tcr-20-3110. Transl Cancer Res. 2020. PMID: 35117359 Free PMC article.
Intracellular accumulation of apoptosis-related proteins Bcl-xl and caspase-3 decreased but C-C3 increased. We also found downregulation of MMP-2 expression, a protein related to invasion and migration (P<0.01), and a decrease in the expression levels of the Wnt/ …
Intracellular accumulation of apoptosis-related proteins Bcl-xl and caspase-3 decreased but C-C3 increased. We also found down …
Diagnostic significance of peritubular capillary basement membrane multilaminations in kidney allografts: old concepts revisited.
Liapis G, Singh HK, Derebail VK, Gasim AM, Kozlowski T, Nickeleit V. Liapis G, et al. Transplantation. 2012 Sep 27;94(6):620-9. doi: 10.1097/TP.0b013e31825f4df4. Transplantation. 2012. PMID: 22936037 Free PMC article.
RESULTS: PTCL was not pathognomonic for any specific disease. PTCL-C/C3 was rare in native kidneys (C, 6%; C3, 1%), associated mainly with late thrombotic microangiopathy (C: 78%; C3: 11% of cases). In allografts, PTCL-C/C3 was significantly more commo …
RESULTS: PTCL was not pathognomonic for any specific disease. PTCL-C/C3 was rare in native kidneys (C, 6%; C3, 1%), associated …
Serum complement C3 and α2-macroglobulin are potentially useful biomarkers for inflammatory bowel disease patients.
Okada K, Itoh H, Ikemoto M. Okada K, et al. Heliyon. 2021 Mar 23;7(3):e06554. doi: 10.1016/j.heliyon.2021.e06554. eCollection 2021 Mar. Heliyon. 2021. PMID: 33851052 Free PMC article.
Hence, the serum levels of c-C3 and alpha(2)-MG could be good indicators of the severity of UC. CONCLUSION: Serum c-C3 and alpha(2)-MG are suitable biomarkers for monitoring the condition of patients with UC....
Hence, the serum levels of c-C3 and alpha(2)-MG could be good indicators of the severity of UC. CONCLUSION: Serum c- …
Detection and Quantification of ADP-Ribosylated RhoA/B by Monoclonal Antibody.
Rohrbeck A, Fühner V, Schröder A, Hagemann S, Vu XK, Berndt S, Hust M, Pich A, Just I. Rohrbeck A, et al. Toxins (Basel). 2016 Apr 1;8(4):100. doi: 10.3390/toxins8040100. Toxins (Basel). 2016. PMID: 27043630 Free PMC article.
Clostridium botulinum exoenzyme C3 is the prototype of C3-like ADP-ribosyltransferases that modify the GTPases RhoA, B, and C. C3 catalyzes the transfer of an ADP-ribose moiety from the co-substrate nicotinamide adenine dinucleotide (NAD) to asparagine-41 of Rho-GTP …
Clostridium botulinum exoenzyme C3 is the prototype of C3-like ADP-ribosyltransferases that modify the GTPases RhoA, B, and C. C3 …
How Strain-Release Determines Chemoselectivity: A Mechanistic Study of Rhodium-Catalyzed Bicyclo[1.1.0]butane Activation.
Lai W, Zhong K, Liu S, Liu S, Chen H, Ni H, Zeng Z, Zhao Z, Lan Y, Bai R. Lai W, et al. J Phys Chem Lett. 2022 Aug 25;13(33):7694-7701. doi: 10.1021/acs.jpclett.2c01528. Epub 2022 Aug 12. J Phys Chem Lett. 2022. PMID: 35960186
In this work, three BCB-activation modes in Rh-catalyzed BCB transformations that construct diastereoselective alpha-quaternary beta-lactones were investigated by density functional theory calculations. Our results show that, compared with C1-C3 insertion and C-C3 o …
In this work, three BCB-activation modes in Rh-catalyzed BCB transformations that construct diastereoselective alpha-quaternary beta-lactone …
Transforming growth factor-beta2 regulates C3 secretion in monocytes through a protein kinase C-dependent pathway.
Drouin SM, Kiley SC, Carlino JA, Barnum SR. Drouin SM, et al. Mol Immunol. 1998 Jan;35(1):1-11. doi: 10.1016/s0161-5890(98)00014-5. Mol Immunol. 1998. PMID: 9683259
Treatment of U937 cells with the PKC inhibitors, H7 and calphostin C, suppressed TGF-beta2-mediated induction of C3 protein levels, but not mRNA levels, in a dose-dependent manner. At the highest concentrations of H7 and calphostin C, C3 protein levels were inhibite …
Treatment of U937 cells with the PKC inhibitors, H7 and calphostin C, suppressed TGF-beta2-mediated induction of C3 protein levels, but not …
91 results