Machine Learning-Based Prediction of Distant Recurrence Risk and Ribociclib Treatment Effect in HR+/HER2- Early Breast Cancer Using Real-World and NATALEE Data.
Howard FM, Fasching PA, Santa-Maria CA, Lim E, Sparano JA, Lustberg MB, Bachelot T, Blyuss O, Brezden-Masley C, Park YH, Akdere M, Ye F, Pantoja K, Kurz C, Dominguez Castro P, Razavi P.
Howard FM, et al.
Clin Cancer Res. 2026 Jan 16;32(2):428-437. doi: 10.1158/1078-0432.CCR-25-1946.
Clin Cancer Res. 2026.
PMID: 41213110
Free PMC article.
Prediction and outcome concordance for distant recurrence and treatment effect were analyzed with Harrell's concordance index (C-index) and integrated Brier score; model performance over time was determined by dynamic AUC analysis. ...External validation with the NATALEE n …
Prediction and outcome concordance for distant recurrence and treatment effect were analyzed with Harrell's concordance index (C-inde …