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Page 1
Chan-Lam-Type C-S Coupling Reaction by Sodium Aryl Sulfinates and Organoboron Compounds.
Lam LY, Ma C. Lam LY, et al. Org Lett. 2021 Aug 6;23(15):6164-6168. doi: 10.1021/acs.orglett.1c02299. Epub 2021 Jul 22. Org Lett. 2021. PMID: 34292759
A Chan-Lam-type C-S coupling reaction using sodium aryl sulfinates has been developed to provide diaryl thioethers in up to 92% yields in the presence of a copper catalyst and potassium sulfite. ...
A Chan-Lam-type C-S coupling reaction using sodium aryl sulfinates has been developed to provide diaryl thioethers in up to 92 …
[E.A+B+C].
[No authors listed] [No authors listed] Zhonghua Fu Chan Ke Za Zhi. 2023 Feb 25;58(2):157-160. doi: 10.3760/cma.j.cn112141-20220616-00389. Zhonghua Fu Chan Ke Za Zhi. 2023. PMID: 36776007 Chinese.
Cryo-EM structure of the human cardiac myosin filament.
Dutta D, Nguyen V, Campbell KS, Padrón R, Craig R. Dutta D, et al. Nature. 2023 Nov;623(7988):853-862. doi: 10.1038/s41586-023-06691-4. Epub 2023 Nov 1. Nature. 2023. PMID: 37914935 Free PMC article.
In addition to myosin, the filaments contain cardiac myosin-binding protein C (cMyBP-C), which modulates contractility in response to physiological stimuli, and titin, which functions as a scaffold for filament assembly(1). ...The packing of myosin tails in the fila …
In addition to myosin, the filaments contain cardiac myosin-binding protein C (cMyBP-C), which modulates contractility in resp …
Atroposelective Chan-Evans-Lam Amination.
Thönnißen V, Westphäling J, Atodiresei IL, Patureau FW. Thönnißen V, et al. Chemistry. 2024 Mar 15;30(16):e202304378. doi: 10.1002/chem.202304378. Epub 2024 Jan 23. Chemistry. 2024. PMID: 38179829
The synthetic control of atropoisomerism along C-N bonds is a major challenge, and methods that allow C-N atroposelective bond formation are rare. ...Yet, among the three most practical and applicable classical amination methods available: 1) the Cu-catalyzed Ullman …
The synthetic control of atropoisomerism along C-N bonds is a major challenge, and methods that allow C-N atroposelective bond …
Hepatitis C.
Chan J. Chan J. Dis Mon. 2014 May;60(5):201-12. doi: 10.1016/j.disamonth.2014.04.002. Dis Mon. 2014. PMID: 24863270 Review. No abstract available.
Cori Bargmann.
Bargmann C. Bargmann C. Neuron. 2024 Sep 25;112(18):2999-3002. doi: 10.1016/j.neuron.2024.09.008. Neuron. 2024. PMID: 39326389
In an interview with Neuron, Cori Bargmann discusses C. elegans as a model organism, the importance of considering the animal's own world (thinking like a worm), choosing a scientific problem, and her experience as head of science at the Chan Zuckerberg Initiative a …
In an interview with Neuron, Cori Bargmann discusses C. elegans as a model organism, the importance of considering the animal's own w …
First atroposelective Chan-Lam coupling for the synthesis of C-N linked biaryls.
Ishida M, Adachi R, Kobayashi K, Yamamoto Y, Kawahara C, Yamada T, Aoyama H, Kanomata K, Akai S, Lam PYS, Sajiki H, Ikawa T. Ishida M, et al. Chem Commun (Camb). 2024 Jan 16;60(6):678-681. doi: 10.1039/d3cc05447k. Chem Commun (Camb). 2024. PMID: 38165949
The first atroposelective Chan-Lam coupling for the synthesis of C-N axial enantiomers is reported with good yields and ee. ...The longstanding problem of the lack of enantioselective synthesis to make chiral C-N linked atropisomers is solved....
The first atroposelective Chan-Lam coupling for the synthesis of C-N axial enantiomers is reported with good yields and ee. .. …
Stereoselective C-terminal peptide elongation from Chan-Lam-Evans reaction generated isopropenyl esters.
Steemers L , van Maarseveen JH . Steemers L , et al. Org Biomol Chem. 2019 Feb 20;17(8):2103-2106. doi: 10.1039/c8ob02102c. Org Biomol Chem. 2019. PMID: 30714599
C-Terminal dipeptide isopropenyl esters were synthesised by a Cu(ii)-mediated Chan-Lam-Evans enol esterification of peptide carboxylic acids and isoprenyl boroxine. ...
C-Terminal dipeptide isopropenyl esters were synthesised by a Cu(ii)-mediated Chan-Lam-Evans enol esterification of peptide ca …
Schools, Children and Myopia.
Congdon N, Chan VF. Congdon N, et al. Am J Ophthalmol. 2023 Oct;254:A1-A3. doi: 10.1016/j.ajo.2023.07.008. Epub 2023 Jul 16. Am J Ophthalmol. 2023. PMID: 37463629 No abstract available.
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