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17,951 results

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Page 1
Hepatitis C.
Chan J. Chan J. Dis Mon. 2014 May;60(5):201-12. doi: 10.1016/j.disamonth.2014.04.002. Dis Mon. 2014. PMID: 24863270 Review. No abstract available.
Atroposelective Chan-Evans-Lam Amination.
Thönnißen V, Westphäling J, Atodiresei IL, Patureau FW. Thönnißen V, et al. Chemistry. 2024 Mar 15;30(16):e202304378. doi: 10.1002/chem.202304378. Epub 2024 Jan 23. Chemistry. 2024. PMID: 38179829
The synthetic control of atropoisomerism along C-N bonds is a major challenge, and methods that allow C-N atroposelective bond formation are rare. ...Yet, among the three most practical and applicable classical amination methods available: 1) the Cu-catalyzed Ullman …
The synthetic control of atropoisomerism along C-N bonds is a major challenge, and methods that allow C-N atroposelective bond …
Cori Bargmann.
Bargmann C. Bargmann C. Neuron. 2024 Sep 25;112(18):2999-3002. doi: 10.1016/j.neuron.2024.09.008. Neuron. 2024. PMID: 39326389 Free article.
In an interview with Neuron, Cori Bargmann discusses C. elegans as a model organism, the importance of considering the animal's own world (thinking like a worm), choosing a scientific problem, and her experience as head of science at the Chan Zuckerberg Initiative a …
In an interview with Neuron, Cori Bargmann discusses C. elegans as a model organism, the importance of considering the animal's own w …
Transition-metal-catalyzed enantioselective C-N cross-coupling.
Feng J, Xi LL, Lu CJ, Liu RR. Feng J, et al. Chem Soc Rev. 2024 Sep 30;53(19):9560-9581. doi: 10.1039/d4cs00102h. Chem Soc Rev. 2024. PMID: 39171573 Review.
Among the accomplishments in chiral amine synthesis, transition-metal-catalyzed enantioselective C-N cross-coupling is considered one of the most efficient protocols. This approach combines traditional C(sp(2))-N cross-coupling methods (such as the Buchwald-Hartwig …
Among the accomplishments in chiral amine synthesis, transition-metal-catalyzed enantioselective C-N cross-coupling is considered one …
Chan-Lam-Type C-S Coupling Reaction by Sodium Aryl Sulfinates and Organoboron Compounds.
Lam LY, Ma C. Lam LY, et al. Org Lett. 2021 Aug 6;23(15):6164-6168. doi: 10.1021/acs.orglett.1c02299. Epub 2021 Jul 22. Org Lett. 2021. PMID: 34292759
A Chan-Lam-type C-S coupling reaction using sodium aryl sulfinates has been developed to provide diaryl thioethers in up to 92% yields in the presence of a copper catalyst and potassium sulfite. ...
A Chan-Lam-type C-S coupling reaction using sodium aryl sulfinates has been developed to provide diaryl thioethers in up to 92 …
[E.A+B+C].
[No authors listed] [No authors listed] Zhonghua Fu Chan Ke Za Zhi. 2023 Feb 25;58(2):157-160. doi: 10.3760/cma.j.cn112141-20220616-00389. Zhonghua Fu Chan Ke Za Zhi. 2023. PMID: 36776007 Chinese.
Stereoselective C-terminal peptide elongation from Chan-Lam-Evans reaction generated isopropenyl esters.
Steemers L , van Maarseveen JH . Steemers L , et al. Org Biomol Chem. 2019 Feb 20;17(8):2103-2106. doi: 10.1039/c8ob02102c. Org Biomol Chem. 2019. PMID: 30714599
C-Terminal dipeptide isopropenyl esters were synthesised by a Cu(ii)-mediated Chan-Lam-Evans enol esterification of peptide carboxylic acids and isoprenyl boroxine. ...
C-Terminal dipeptide isopropenyl esters were synthesised by a Cu(ii)-mediated Chan-Lam-Evans enol esterification of peptide ca …
First atroposelective Chan-Lam coupling for the synthesis of C-N linked biaryls.
Ishida M, Adachi R, Kobayashi K, Yamamoto Y, Kawahara C, Yamada T, Aoyama H, Kanomata K, Akai S, Lam PYS, Sajiki H, Ikawa T. Ishida M, et al. Chem Commun (Camb). 2024 Jan 16;60(6):678-681. doi: 10.1039/d3cc05447k. Chem Commun (Camb). 2024. PMID: 38165949
The first atroposelective Chan-Lam coupling for the synthesis of C-N axial enantiomers is reported with good yields and ee. ...The longstanding problem of the lack of enantioselective synthesis to make chiral C-N linked atropisomers is solved....
The first atroposelective Chan-Lam coupling for the synthesis of C-N axial enantiomers is reported with good yields and ee. .. …
Enantioselective Chan-Lam S-Arylation of Sulfenamides.
Liang Q, Zhang X, Rotella ME, Xu Z, Kozlowski MC, Jia T. Liang Q, et al. Nat Catal. 2024 Sep;7:1010-1020. doi: 10.1038/s41929-024-01213-5. Epub 2024 Sep 9. Nat Catal. 2024. PMID: 41293477 Free PMC article.
We report a highly chemoselective and enantioselective Chan-Lam S-arylation of sulfenamides with arylboronic acids to deliver an array of thermodynamically disfavored diaryl and alkyl aryl sulfilimines containing a sulfur stereocenter. Though Chan-Lam coupling has b …
We report a highly chemoselective and enantioselective Chan-Lam S-arylation of sulfenamides with arylboronic acids to deliver an arra …
Hepatitis C Virus-Induced Autophagy and Host Innate Immune Response.
Chan ST, Ou JJ. Chan ST, et al. Viruses. 2017 Aug 12;9(8):224. doi: 10.3390/v9080224. Viruses. 2017. PMID: 28805674 Free PMC article. Review.
This pathway in hepatocytes is stimulated and controlled by the hepatitis C virus (HCV)-upon infection-to promote its own replication. HCV induces autophagy indirectly and directly through different mechanisms and temporally controls the autophagic flux. ...
This pathway in hepatocytes is stimulated and controlled by the hepatitis C virus (HCV)-upon infection-to promote its own replication …
17,951 results
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