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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1968 1
1973 1
1975 1
1976 3
1977 6
1978 3
1979 2
1980 3
1981 2
1982 6
1983 3
1984 4
1985 2
1986 3
1988 4
1989 3
1990 7
1991 9
1992 12
1993 4
1994 8
1995 13
1996 11
1997 16
1998 11
1999 15
2000 15
2001 15
2002 13
2003 24
2004 17
2005 23
2006 24
2007 11
2008 21
2009 23
2010 21
2011 23
2012 31
2013 24
2014 33
2015 45
2016 57
2017 51
2018 42
2019 21
2020 27
2021 21
2022 28
2023 26
2024 17
2025 23
2026 9

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775 results

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Page 1
Electrocardiographic patterns of accidental hypothermia.
Okumura H, Okada N, Hamanaka K, Okada Y, Kitamura T, Matsuyama T. Okumura H, et al. Am J Emerg Med. 2025 Apr;90:210-213. doi: 10.1016/j.ajem.2025.01.079. Epub 2025 Jan 30. Am J Emerg Med. 2025. PMID: 39933216
METHODS: We conducted a retrospective analysis using the J-POINT registry, which included patients with body temperatures 35 C who visited the emergency departments of 12 Japanese institutions between April 1, 2011, and March 31, 2016. ...
METHODS: We conducted a retrospective analysis using the J-POINT registry, which included patients with body temperatures 35 C …
Effect of phosphoproteins on intracellular calcification of bacteria.
Yoshikuni Y, Iijima M, Takahashi G, Okumura T, Kogure T, Suzuki M. Yoshikuni Y, et al. Eur J Oral Sci. 2023 Jun;131(3):e12929. doi: 10.1111/eos.12929. Epub 2023 Mar 17. Eur J Oral Sci. 2023. PMID: 36929523
To evaluate mineralization independent of bacterial metabolism, bacteria killed by heat treatment at 70 C were compared with viable bacteria. After incubation at 37 C for 24 h, the mode of calcification was observed using electron microscopy and energy dispersive x- …
To evaluate mineralization independent of bacterial metabolism, bacteria killed by heat treatment at 70 C were compared with viable b …
PCAF modulates PTEN activity.
Okumura K, Mendoza M, Bachoo RM, DePinho RA, Cavenee WK, Furnari FB. Okumura K, et al. J Biol Chem. 2006 Sep 8;281(36):26562-8. doi: 10.1074/jbc.M605391200. Epub 2006 Jul 7. J Biol Chem. 2006. PMID: 16829519 Free article.
The lipid phosphoinositol phosphatase activity is essential for PTEN to block the cell cycle in the G1 phase and thereby to suppress tumor formation and progression (Cantley, L. C., and Neel, B. G. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 4240-4245), although the mechani …
The lipid phosphoinositol phosphatase activity is essential for PTEN to block the cell cycle in the G1 phase and thereby to suppress tumor f …
CDK1-mediated CENP-C phosphorylation modulates CENP-A binding and mitotic kinetochore localization.
Watanabe R, Hara M, Okumura EI, Hervé S, Fachinetti D, Ariyoshi M, Fukagawa T. Watanabe R, et al. J Cell Biol. 2019 Dec 2;218(12):4042-4062. doi: 10.1083/jcb.201907006. Epub 2019 Nov 1. J Cell Biol. 2019. PMID: 31676716 Free PMC article.
As CENP-C is a hub protein for kinetochore assembly, it is critical to address how the CENP-A-CENP-C interaction is regulated during cell cycle progression. To address this question, we investigated the CENP-C C-terminal region, including a conserved C …
As CENP-C is a hub protein for kinetochore assembly, it is critical to address how the CENP-A-CENP-C interaction is regulated …
Cryo-EM structure of the CENP-A nucleosome in complex with phosphorylated CENP-C.
Ariyoshi M, Makino F, Watanabe R, Nakagawa R, Kato T, Namba K, Arimura Y, Fujita R, Kurumizaka H, Okumura EI, Hara M, Fukagawa T. Ariyoshi M, et al. EMBO J. 2021 Mar 1;40(5):e105671. doi: 10.15252/embj.2020105671. Epub 2021 Jan 19. EMBO J. 2021. PMID: 33463726 Free PMC article.
Once the CENP-A nucleosome is established in the centromere, additional proteins recognize the CENP-A nucleosome to form a kinetochore. CENP-C and CENP-N are CENP-A binding proteins. We previously demonstrated that vertebrate CENP-C binding to the CENP-A nucleosome …
Once the CENP-A nucleosome is established in the centromere, additional proteins recognize the CENP-A nucleosome to form a kinetochore. CENP …
Paroxysmal Kinesigenic Dyskinesia in Two Siblings With Novel Heterozygous TMEM151A Frameshift Variant: The First Case Report in Japan.
Kurahashi H, Azuma Y, Takeuchi T, Shimada M, Numoto S, Nishida M, Ito Y, Ogi T, Okumura A. Kurahashi H, et al. Am J Med Genet A. 2025 Aug;197(8):e64079. doi: 10.1002/ajmg.a.64079. Epub 2025 Apr 1. Am J Med Genet A. 2025. PMID: 40167178
Here, we report the cases of two Japanese siblings diagnosed with paroxysmal kinesigenic dyskinesia caused by a novel heterozygous TMEM151A frameshift variant (c.760_761insT). Case 1 was a 17-year-old male who had experienced involuntary movements triggered by sudden actio …
Here, we report the cases of two Japanese siblings diagnosed with paroxysmal kinesigenic dyskinesia caused by a novel heterozygous TMEM151A …
Hereditary Fibrinogen Aα-Chain Amyloidosis in Asia: Clinical and Molecular Characteristics.
Yazaki M, Yoshinaga T, Sekijima Y, Kametani F, Okumura N. Yazaki M, et al. Int J Mol Sci. 2018 Jan 22;19(1):320. doi: 10.3390/ijms19010320. Int J Mol Sci. 2018. PMID: 29361747 Free PMC article. Review.
In molecular features in Asian Aalpha-chain amyloidosis, the most common variant, E526V, was found in only one Chinese kindred, and other four kindred each had a different variant, which have not been identified in other countries. These variants are located in the C-termi …
In molecular features in Asian Aalpha-chain amyloidosis, the most common variant, E526V, was found in only one Chinese kindred, and other fo …
Nicolaioidesin C: An Antiausterity Agent Shows Promising Antitumor Activity in a Pancreatic Cancer Xenograft Mouse Model.
Phan ND, Omar AM, Takahashi I, Baba H, Okumura T, Imura J, Okada T, Toyooka N, Fujii T, Awale S. Phan ND, et al. J Nat Prod. 2023 Jun 23;86(6):1402-1410. doi: 10.1021/acs.jnatprod.3c00019. Epub 2023 Mar 20. J Nat Prod. 2023. PMID: 36938707
Furthermore, Nic-C inhibited the Akt/mTOR and autophagy signaling pathways in both in vitro and in vivo studies. Metabolomic profiling of in vivo tumor samples suggests that Nic-C downregulates amino acid metabolism while upregulating sphingolipid metabolism....
Furthermore, Nic-C inhibited the Akt/mTOR and autophagy signaling pathways in both in vitro and in vivo studies. Metabolomic profilin …
775 results