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Page 1
(177)Lu-DOTA-Tyr(3)-c(Cys-Tyr-Trp-Lys-Thr-Cys)-Thr-Lys(cypate)-NH(2).
Zhang H. Zhang H. 2008 Mar 20 [updated 2008 Apr 22]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. 2008 Mar 20 [updated 2008 Apr 22]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. PMID: 20641372 Free Books & Documents. Review.
In addition to symptomatic treatment of tumors in clinic, these analogs are also labeled with a variety of probes for imaging (1). (177)Lu-DOTA-Tyr(3)-c(Cys-Tyr-Trp-Lys-Thr-Cys)-Thr-Lys(cypate)-NH(2)((177)Lu-LS172) is a monomolecular multimodal imaging agent …
In addition to symptomatic treatment of tumors in clinic, these analogs are also labeled with a variety of probes for imaging (1). (177)L …
Stabilizing a non-IPR C(2)(13333)-C(74) cage with Lu(2)C(2)/Lu(2)O: the importance of encaged non-metallic elements.
Yu P, Li M, Hu S, Pan C, Shen W, Guo K, Xie YP, Bao L, Zhang R, Lu X. Yu P, et al. Chem Commun (Camb). 2023 Oct 31;59(87):12990-12993. doi: 10.1039/d3cc04668k. Chem Commun (Camb). 2023. PMID: 37831442
A difference in encaged non-metallic element (i.e., C(2)versus O) leads to a clear change of intramolecular interactions and shifts in redox potentials of Lu(2)C(2)@C(2)(13333)-C(74) and Lu(2)O@C(2)(13333)-C(74), as a result …
A difference in encaged non-metallic element (i.e., C(2)versus O) leads to a clear change of intramolecular interactions and shifts i …
[(68)Ga]Ga/[(177)Lu]Lu-BL01, a Novel Theranostic Pair for Targeting C-X-C Chemokine Receptor 4.
Lau J, Kwon D, Rousseau E, Zhang Z, Zeisler J, Uribe CF, Kuo HT, Zhang C, Lin KS, Bénard F. Lau J, et al. Mol Pharm. 2019 Nov 4;16(11):4688-4695. doi: 10.1021/acs.molpharmaceut.9b00808. Epub 2019 Oct 4. Mol Pharm. 2019. PMID: 31545614
C-X-C chemokine receptor type 4 (CXCR4) is overexpressed in hematological and solid malignancies. ...PET imaging studies were performed with [(68)Ga]Ga-BL01, with blocking experiments performed with preinjection of LY2510924. The stability of [(68)Ga]Ga/[(177)Lu …
C-X-C chemokine receptor type 4 (CXCR4) is overexpressed in hematological and solid malignancies. ...PET imaging studies were …
Glycophorin-C sialylation regulates Lu/BCAM adhesive capacity during erythrocyte aging.
Klei TRL, de Back DZ, Asif PJ, Verkuijlen PJJH, Veldthuis M, Ligthart PC, Berghuis J, Clifford E, Beuger BM, van den Berg TK, van Zwieten R, El Nemer W, van Bruggen R. Klei TRL, et al. Blood Adv. 2018 Jan 3;2(1):14-24. doi: 10.1182/bloodadvances.2017013094. eCollection 2018 Jan 9. Blood Adv. 2018. PMID: 29344581 Free PMC article.
Following loss of sialic acid during erythrocyte aging, Lu/BCAM is released from glycophorin-C and allowed to interact with sialic acid residues on laminin-alpha5. Decreased glycophorin-C sialylation, as observed in individuals lacking exon 3 of glycophorin- …
Following loss of sialic acid during erythrocyte aging, Lu/BCAM is released from glycophorin-C and allowed to interact with si …
Preclinical Evaluation of (177)Lu-OncoFAP-23, a Multivalent FAP-Targeted Radiopharmaceutical Therapeutic for Solid Tumors.
Galbiati A, Bocci M, Ravazza D, Mock J, Gilardoni E, Neri D, Cazzamalli S. Galbiati A, et al. J Nucl Med. 2024 Oct 1;65(10):1604-1610. doi: 10.2967/jnumed.124.268200. J Nucl Med. 2024. PMID: 39266289
Methods: OncoFAP-23 was radiolabeled with the theranostic radionuclide (177)Lu. Preclinical experiments were conducted on mice bearing SK-RC-52.hFAP (BALB/c nude mice) or CT-26.hFAP (BALB/c mice) tumors. (177)Lu-OncoFAP and (177)Lu-FAP-2286 were …
Methods: OncoFAP-23 was radiolabeled with the theranostic radionuclide (177)Lu. Preclinical experiments were conducted on mice bearin …
Targeting CXCR4/CXCL12 axis via [(177)Lu]Lu-DOTAGA.(SA.FAPi)(2) with CXCR4 antagonist in triple-negative breast cancer.
Bao G, Wang Z, Liu L, Zhang B, Song S, Wang D, Cheng S, Moon ES, Roesch F, Zhao J, Yu B, Zhu X. Bao G, et al. Eur J Nucl Med Mol Imaging. 2024 Jul;51(9):2744-2757. doi: 10.1007/s00259-024-06704-y. Epub 2024 Apr 8. Eur J Nucl Med Mol Imaging. 2024. PMID: 38587644 Free PMC article.
But radiopharmaceuticals alone in most cases are insufficient to completely eradicate tumor cells, which can partially be attributed to the protective interplay between tumor cells and cancer-associated fibroblasts (CAFs). The C-X-C chemokine receptor type 4/C …
But radiopharmaceuticals alone in most cases are insufficient to completely eradicate tumor cells, which can partially be attributed to the …
(177)Lu-DOTA-Gly-4-aminobenzoyl-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH(2).
Zhang H. Zhang H. 2008 Oct 1 [updated 2008 Nov 17]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. 2008 Oct 1 [updated 2008 Nov 17]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. PMID: 20641607 Free Books & Documents. Review.
Gastrin-releasing peptide (GRP) is a peptide of 27 amino acids from porcine gastric tissues with Gly-His-Leu-Met at its C-terminus. Neuromedin B (NMB) is a peptide of 32 amino acids from porcine spinal cords with Gly-His-Phe-Met at its C-terminus. ...Thus, tagging G …
Gastrin-releasing peptide (GRP) is a peptide of 27 amino acids from porcine gastric tissues with Gly-His-Leu-Met at its C-terminus. N …
Steering Lu(3)N clusters in C(76-78) cages: cluster configuration dominated by cage transformation.
Yu P, Hu S, Tian X, Shen W, Yu P, Guo K, Xie Y, Bao L, Lu X. Yu P, et al. Nanoscale. 2022 Dec 1;14(46):17290-17296. doi: 10.1039/d2nr05049h. Nanoscale. 2022. PMID: 36377636
For this purpose, we herein synthesized three metallofullerene molecules with an easy-to-compare cluster configuration and cage arrangement, namely Lu(3)N@C(s)(17 490)-C(76), Lu(3)N@C(2)(22 010)-C(78), and Lu(3)N@D(3h)(5)-C( …
For this purpose, we herein synthesized three metallofullerene molecules with an easy-to-compare cluster configuration and cage arrangement, …
Significant Roles of a Particularly Stable Two-Center Two-Electron Lu-Lu sigma Bond in Lu(2)@C(86): Electronic Structure of Lu and Radius of Lu(2).
Zhang K, Zheng H, Li M, Li QZ, Zhao Y, Zhao X. Zhang K, et al. Inorg Chem. 2021 Feb 15;60(4):2425-2436. doi: 10.1021/acs.inorgchem.0c03336. Epub 2021 Jan 26. Inorg Chem. 2021. PMID: 33497217
Inevitably, besides the experimentally reported Lu(2)@C(2v)(63751)-C(86), Lu(2)@C(s)(63750)-C(86), and Lu(2)@C(s)(63757)-C(86), other three metal carbide clusterfullerenes, Lu(2)C(2)@D(2d)(51591)-C …
Inevitably, besides the experimentally reported Lu(2)@C(2v)(63751)-C(86), Lu(2)@C(s)(63750)-C(86), …
Crystallographic characterization of Lu(2)C(2n) (2n = 76-90): cluster selection by cage size.
Shen W, Bao L, Hu S, Yang L, Jin P, Xie Y, Akasaka T, Lu X. Shen W, et al. Chem Sci. 2018 Oct 30;10(3):829-836. doi: 10.1039/c8sc03886d. eCollection 2019 Jan 21. Chem Sci. 2018. PMID: 30774877 Free PMC article.
The molecular structures of these compounds are unambiguously assigned as Lu(2)@T (d)(2)-C(76), Lu(2)@D (3h)(5)-C(78), Lu(2)@C (2v)(5)-C(80), Lu(2)@C (2v)(7)-C(84), Lu(2)@C (s)(8)-C(86), …
The molecular structures of these compounds are unambiguously assigned as Lu(2)@T (d)(2)-C(76), Lu(2)@D (3h)(5)-C …
57,693 results
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