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28 results

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Page 1
DMD Genotypes and Motor Function in Duchenne Muscular Dystrophy: A Multi-institution Meta-analysis With Implications for Clinical Trials.
Muntoni F, Signorovitch J, Sajeev G, Lane H, Jenkins M, Dieye I, Ward SJ, McDonald C, Goemans N, Niks EH, Wong B, Servais L, Straub V, Guglieri M, de Groot IJM, Chesshyre M, Tian C, Manzur AY, Mercuri E, Aartsma-Rus A; Association Française Contre Les Myopathies; on behalf of Universitaire Ziekenhuizen Leuven Group, PRO-DMD-01, The UK NorthStar Clinical Network, CCHMC, and The DMD Italian Group. Muntoni F, et al. Neurology. 2023 Apr 11;100(15):e1540-e1554. doi: 10.1212/WNL.0000000000201626. Epub 2023 Feb 1. Neurology. 2023. PMID: 36725339 Free PMC article.
Controlled meta-Selective C-H Mono- and Di-Olefination of Mandelic Acid Derivatives.
Muthuraja P, Usman R, Sajeev R, Gopinath P. Muthuraja P, et al. Org Lett. 2021 Aug 6;23(15):6014-6018. doi: 10.1021/acs.orglett.1c02080. Epub 2021 Jul 19. Org Lett. 2021. PMID: 34279109
The synthesis of functionalized homatropine and cyclandelate drug derivatives was demonstrated. Kinetic isotope effects revealed C-H activation as the rate-limiting step....
The synthesis of functionalized homatropine and cyclandelate drug derivatives was demonstrated. Kinetic isotope effects revealed C-H …
Baseline C-reactive protein levels and prognosis in patients with infective endocarditis: A prospective cohort study.
Mohanan S, Gopalan Nair R, Vellani H, C G S, George B, M N K. Mohanan S, et al. Indian Heart J. 2018 Dec;70 Suppl 3(Suppl 3):S43-S49. doi: 10.1016/j.ihj.2018.05.001. Epub 2018 May 17. Indian Heart J. 2018. PMID: 30595302 Free PMC article.
A simple tool that can predict adverse outcomes in the early phase of management is required. AIM: To study the prognostic value of C-reactive protein (CRP) levels at admission and its role in predicting various clinical outcomes. ...
A simple tool that can predict adverse outcomes in the early phase of management is required. AIM: To study the prognostic value of C …
Assessing Patient Preferences for Treatment Decisions for New Direct Acting Antiviral (DAA) Therapies for Chronic Hepatitis C Virus Infections.
Welzel TM, Yang M, Sajeev G, Chen YJ, Pinsky B, Bao Y, Wu EQ, Dieterich D. Welzel TM, et al. Adv Ther. 2019 Sep;36(9):2475-2486. doi: 10.1007/s12325-019-01012-6. Epub 2019 Jun 25. Adv Ther. 2019. PMID: 31240629 Free PMC article.
INTRODUCTION: The new direct acting antiviral (DAA) therapies are able to effectively treat chronic hepatitis C (CHC). This study elicited the preferences of CHC patients for treatment attributes of new DAAs. ...
INTRODUCTION: The new direct acting antiviral (DAA) therapies are able to effectively treat chronic hepatitis C (CHC). This study eli …
Antiviral radical SAM enzyme viperin homologue from Asian seabass (Lates calcarifer): Molecular characterisation and expression analysis.
Raji Sathyan K, Premraj A, Thavarool Puthiyedathu S. Raji Sathyan K, et al. Dev Comp Immunol. 2022 Nov;136:104499. doi: 10.1016/j.dci.2022.104499. Epub 2022 Aug 3. Dev Comp Immunol. 2022. PMID: 35931216
This cloned viperin cDNA encodes 351 amino acid protein with predicted N-terminal amphipathic alpha-helix, conserved radical S-adenosyl l-methionine (SAM) domain with CxxxCxxC motif and a highly conserved C-terminal domain. Lcviperin gene consists of six exons and five int …
This cloned viperin cDNA encodes 351 amino acid protein with predicted N-terminal amphipathic alpha-helix, conserved radical S-adenosyl l-me …
Comparative stability study and aggregate analysis of Bevacizumab marketed formulations using advanced analytical techniques.
Bana AA, Sajeev N, Halder S, Abbas Masi H, Patel S, Mehta P. Bana AA, et al. Heliyon. 2023 Aug 28;9(9):e19478. doi: 10.1016/j.heliyon.2023.e19478. eCollection 2023 Sep. Heliyon. 2023. PMID: 37810070 Free PMC article.
Furthermore, Bvz formulations under study were subjected to various stress conditions of thermal (elevated temperature 50 2 C), chemical (acidic pH 3.0 0.2, neutral pH 7.0 0.2, and basic pH 10.0 0.2), and mechanical (agitation 200 rpm) for comparative stability evaluation. …
Furthermore, Bvz formulations under study were subjected to various stress conditions of thermal (elevated temperature 50 2 C), chemi …
Substituent-Controlled Photophysical Responses in Dihydropyridine Derivatives and Their Application in the Detection of Volatile Organic Contaminants.
Kanneth SS, Mathew D, Parameswaran P, Sajeev AK, Unni KNN, Chakkumkumarath L. Kanneth SS, et al. J Org Chem. 2023 Nov 3;88(21):15007-15017. doi: 10.1021/acs.joc.3c01455. Epub 2023 Oct 20. J Org Chem. 2023. PMID: 37862461
Herein, we describe a series of solid-emissive N-substituted 2,6-dimethyl-4-methylene-1,4-dihydropyridine derivatives appended with electron-withdrawing substituents (dicyanomethylene or 2-dicyanomethylene-3-cyano-2,5-dihydrofuran) at the C-4 position and alkyl or alkylary …
Herein, we describe a series of solid-emissive N-substituted 2,6-dimethyl-4-methylene-1,4-dihydropyridine derivatives appended with electron …
28 results