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1-Dichloro-acetyl-r-2,c-6-bis-(4-methoxy-phen-yl)-t-3-methyl-piperidin-4-one.
Ravichandran K, Ramesh P, Sakthivel P, Ponnuswamy S, Ponnuswamy MN. Ravichandran K, et al. Acta Crystallogr Sect E Struct Rep Online. 2010 Jan 9;66(Pt 2):o262. doi: 10.1107/S1600536809054713. Acta Crystallogr Sect E Struct Rep Online. 2010. PMID: 21579703 Free PMC article.
In the title compound, C(22)H(23)Cl(2)NO(4), the piperidine ring adopts a distorted boat conformation. ...The benzene rings are oriented at angles of 84.3 (1) and 76.8 (1) with respect to the best plane through the piperidine ring. The crystal packing is stabilized by inte …
In the title compound, C(22)H(23)Cl(2)NO(4), the piperidine ring adopts a distorted boat conformation. ...The benzene rings are orien …
1-(3,5-Dimethyl-phen-yl)-2-(4-fluoro-phen-yl)-1H-phenanthro[9,10-d]imidazole.
Sathishkumar R, Mohandas T, Sakthivel P, Jayabharathi J. Sathishkumar R, et al. Acta Crystallogr Sect E Struct Rep Online. 2013 Mar 1;69(Pt 3):o367. doi: 10.1107/S1600536813003486. Epub 2013 Feb 9. Acta Crystallogr Sect E Struct Rep Online. 2013. PMID: 23476556 Free PMC article.
In the title compound, C29H21FN2, the phenanthro tricyclic ring system is essentially planar with a maximum deviation of 0.030 (2) A and makes dihedral angles between of 77.96 (6) and 37.18 (7) with the dimethyl-phenyl and fluoro-phenyl rings, respectively. The crystal packing fe …
In the title compound, C29H21FN2, the phenanthro tricyclic ring system is essentially planar with a maximum deviation of 0.030 (2) A and mak …
Leducq Transatlantic Network of Excellence to Cure Phospholamban-Induced Cardiomyopathy (CURE-PLaN).
Doevendans PA, Glijnis PC, Kranias EG. Doevendans PA, et al. Circ Res. 2019 Sep 13;125(7):720-724. doi: 10.1161/CIRCRESAHA.119.315077. Epub 2019 Sep 12. Circ Res. 2019. PMID: 31513489
We are also privileged to get support from Arthur Wilde (University of Amsterdam), Sakthivel Sadayappan (University of Cincinnati), and Roger Hajjar (Phospholamban Foundation), who have had a long-standing interest in cardiac physiology and pathophysiology with emphasis on …
We are also privileged to get support from Arthur Wilde (University of Amsterdam), Sakthivel Sadayappan (University of Cincinnati), a …
1-Formyl-c-3,t-3-dimethyl-r-2,c-6-di-phenyl-piperidin-4-one.
Ravichandran K, Sakthivel P, Ramesh P, Ponnuswamy S, Ponnuswamy MN. Ravichandran K, et al. Acta Crystallogr Sect E Struct Rep Online. 2012 Mar 1;68(Pt 3):o870. doi: 10.1107/S1600536812007015. Epub 2012 Feb 29. Acta Crystallogr Sect E Struct Rep Online. 2012. PMID: 22412723 Free PMC article.
In the title compound, C(20)H(21)NO(2), the piperidine ring adopts a distorted boat conformation. The phenyl rings substituted at the 2- and 6-positions of the piperidine ring subtend angles of 86.0 (1) and 67.3 (1) with the mean plane of the piperidine ring (all six non-H …
In the title compound, C(20)H(21)NO(2), the piperidine ring adopts a distorted boat conformation. The phenyl rings substituted at the …
t-3-Ethyl-r-2,c-6-bis-(4-methoxy-phen-yl)-1-nitro-sopiperidin-4-one.
Kavitha T, Thenmozhi M, Ponnuswamy S, Sakthivel P, Ponnuswamy MN. Kavitha T, et al. Acta Crystallogr Sect E Struct Rep Online. 2009 Jul 4;65(Pt 8):o1765. doi: 10.1107/S1600536809024878. Acta Crystallogr Sect E Struct Rep Online. 2009. PMID: 21583475 Free PMC article.
In the title mol-ecule, C(21)H(24)N(2)O(4), the piperidine ring adopts a distorted boat conformation with the ethyl substituent in the axial position. The dihedral angle between the two benzene rings is 70.25 (9). An intra-molecular C-HO inter-action is observed. In …
In the title mol-ecule, C(21)H(24)N(2)O(4), the piperidine ring adopts a distorted boat conformation with the ethyl substituent in th …
1-Formyl-r-2,c-6-bis-(4-methoxy-phen-yl)-c-3,t-3-dimethyl-piperidin-4-one.
Kavitha T, Ponnuswamy S, Sakthivel P, Karthik K, Ponnuswamy MN. Kavitha T, et al. Acta Crystallogr Sect E Struct Rep Online. 2009 Mar 25;65(Pt 4):o856. doi: 10.1107/S1600536809010010. Acta Crystallogr Sect E Struct Rep Online. 2009. PMID: 21582573 Free PMC article.
In the title compound, C(22)H(25)NO(4), the piperidine ring adopts a distorted boat conformation. The two benzene rings are approximately perpendicular to each other, making a dihedral angle of 86.2 (8). The crystal packing is stabilized by C-HO and C-Hpi int …
In the title compound, C(22)H(25)NO(4), the piperidine ring adopts a distorted boat conformation. The two benzene rings are approxima …
r-2,c-6-Bis(4-methoxy-phenyl)-c-3,t-3-dimethyl-1-nitro-sopiperidin-4-one.
Kavitha T, Ponnuswamy S, Sakthivel P, Karthik K, Ponnuswamy MN. Kavitha T, et al. Acta Crystallogr Sect E Struct Rep Online. 2009 May 29;65(Pt 6):o1420. doi: 10.1107/S1600536809019357. Acta Crystallogr Sect E Struct Rep Online. 2009. PMID: 21583262 Free PMC article.
In the title compound, C(21)H(24)N(2)O(4), the piperidine ring adopts a distorted boat conformation. The crystal structure is stabilized by C-Hpi inter-actions involving one of the methoxy-phenyl rings....
In the title compound, C(21)H(24)N(2)O(4), the piperidine ring adopts a distorted boat conformation. The crystal structure is stabili …
1-Formyl-t-3,t-5-dimethyl-r-2,c-6-diphenyl-piperidin-4-one.
Ravichandran K, Ramesh P, Sakthivel P, Ponnuswamy S, Ponnuswamy MN. Ravichandran K, et al. Acta Crystallogr Sect E Struct Rep Online. 2010 May 29;66(Pt 6):o1505. doi: 10.1107/S1600536810018490. Acta Crystallogr Sect E Struct Rep Online. 2010. PMID: 21579565 Free PMC article.
In the title compound, C(20)H(21)NO(2), the piperidine ring adopts a distorted boat conformation. The dihedral angle between the two phenyl rings is 61.33 (18). In the crystal, inter-molecular C-HO inter-actions link the mol-ecules into zigzag C(5) chains run …
In the title compound, C(20)H(21)NO(2), the piperidine ring adopts a distorted boat conformation. The dihedral angle between the two …
1-Chloro-acetyl-r-2,c-6-bis-(4-methoxy-phen-yl)-t-3-methyl-piperidin-4-one.
Ravichandran K, Ramesh P, Sakthivel P, Ponnuswamy S, Ponnuswamy MN. Ravichandran K, et al. Acta Crystallogr Sect E Struct Rep Online. 2009 Oct 28;65(Pt 11):o2883. doi: 10.1107/S1600536809043281. Acta Crystallogr Sect E Struct Rep Online. 2009. PMID: 21578468 Free PMC article.
There are two crystallographically independent mol-ecules in the asymmetric unit of the title compound, C(22)H(24)ClNO(4). The piperidine ring in both mol-ecules adopts a distorted boat conformation. The crystal packing is stabilized by C-HO and C-HCl inter-a …
There are two crystallographically independent mol-ecules in the asymmetric unit of the title compound, C(22)H(24)ClNO(4). The piperi …
1-Formyl-r-2,c-6-bis-(4-methoxy-phen-yl)-t-3-methyl-piperidin-4-one.
Gayathri P, Sakthivel P, Ponnuswamy S, Thiruvalluvar A, Butcher RJ. Gayathri P, et al. Acta Crystallogr Sect E Struct Rep Online. 2009 Oct 23;65(Pt 11):o2813. doi: 10.1107/S1600536809042457. Acta Crystallogr Sect E Struct Rep Online. 2009. PMID: 21578404 Free PMC article.
The asymmetric unit of the title compound, C(21)H(23)NO(4), contains two crystallographically independent mol-ecules A and B. ...The dihedral angle between the two benzene rings is 55.27 (8) in mol-ecule A, and 55.29 (8) in mol-ecule B. In the crystal, the mol-ecules are l …
The asymmetric unit of the title compound, C(21)H(23)NO(4), contains two crystallographically independent mol-ecules A and B. ...The …
152 results