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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2003 3
2004 1
2006 2
2007 1
2008 4
2009 3
2010 3
2011 5
2012 2
2013 3
2014 4
2015 6
2016 2
2017 3
2018 2
2019 3
2020 4
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45 results
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Page 1
Clinical relevance of DPYD variants c.1679T>G, c.1236G>A/HapB3, and c.1601G>A as predictors of severe fluoropyrimidine-associated toxicity: a systematic review and meta-analysis of individual patient data.
Meulendijks D, Henricks LM, Sonke GS, Deenen MJ, Froehlich TK, Amstutz U, Largiadèr CR, Jennings BA, Marinaki AM, Sanderson JD, Kleibl Z, Kleiblova P, Schwab M, Zanger UM, Palles C, Tomlinson I, Gross E, van Kuilenburg AB, Punt CJ, Koopman M, Beijnen JH, Cats A, Schellens JH. Meulendijks D, et al. Among authors: largiader cr. Lancet Oncol. 2015 Dec;16(16):1639-50. doi: 10.1016/S1470-2045(15)00286-7. Epub 2015 Oct 23. Lancet Oncol. 2015. PMID: 26603945 Review.
The International Hereditary Thrombotic Thrombocytopenic Purpura Registry: key findings at enrollment until 2017.
van Dorland HA, Taleghani MM, Sakai K, Friedman KD, George JN, Hrachovinova I, Knöbl PN, von Krogh AS, Schneppenheim R, Aebi-Huber I, Bütikofer L, Largiadèr CR, Cermakova Z, Kokame K, Miyata T, Yagi H, Terrell DR, Vesely SK, Matsumoto M, Lämmle B, Fujimura Y, Kremer Hovinga JA; Hereditary TTP Registry. van Dorland HA, et al. Among authors: largiader cr. Haematologica. 2019 Oct;104(10):2107-2115. doi: 10.3324/haematol.2019.216796. Epub 2019 Feb 21. Haematologica. 2019. PMID: 30792199 Free PMC article. Clinical Trial.
Association of the Intestinal Microbiome with the Development of Neovascular Age-Related Macular Degeneration.
Zinkernagel MS, Zysset-Burri DC, Keller I, Berger LE, Leichtle AB, Largiadèr CR, Fiedler GM, Wolf S. Zinkernagel MS, et al. Among authors: largiader cr. Sci Rep. 2017 Jan 17;7:40826. doi: 10.1038/srep40826. Sci Rep. 2017. PMID: 28094305 Free PMC article.
Evaluating the role of ENOSF1 and TYMS variants as predictors in fluoropyrimidine-related toxicities: An IPD meta-analysis.
Hamzic S, Kummer D, Froehlich TK, Joerger M, Aebi S, Palles C, Thomlinson I, Meulendijks D, Schellens JHM, García-González X, López-Fernández LA, Amstutz U, Largiadèr CR. Hamzic S, et al. Among authors: largiader cr. Pharmacol Res. 2020 Feb;152:104594. doi: 10.1016/j.phrs.2019.104594. Epub 2019 Dec 12. Pharmacol Res. 2020. PMID: 31838077 Free article.
Genotype-guided fluoropyrimidine dosing: ready for implementation.
Amstutz U, Largiadèr CR. Amstutz U, et al. Among authors: largiader cr. Lancet Oncol. 2018 Nov;19(11):1421-1422. doi: 10.1016/S1470-2045(18)30744-7. Epub 2018 Oct 19. Lancet Oncol. 2018. PMID: 30348539 No abstract available.
Come a long way, still a ways to go: from predicting and preventing fluoropyrimidine toxicity to increased efficacy?
Hamzic S, Amstutz U, Largiadèr CR. Hamzic S, et al. Among authors: largiader cr. Pharmacogenomics. 2018 Jun 1;19(8):689-692. doi: 10.2217/pgs-2018-0040. Epub 2018 May 22. Pharmacogenomics. 2018. PMID: 29783877 Free article. No abstract available.
Dihydropyrimidinase and β-ureidopropionase gene variation and severe fluoropyrimidine-related toxicity.
Kummer D, Froehlich TK, Joerger M, Aebi S, Sistonen J, Amstutz U, Largiadèr CR. Kummer D, et al. Among authors: largiader cr. Pharmacogenomics. 2015;16(12):1367-77. doi: 10.2217/pgs.15.81. Epub 2015 Aug 5. Pharmacogenomics. 2015. PMID: 26244261
Phenotypic and clinical implications of variants in the dihydropyrimidine dehydrogenase gene.
Kuilenburg ABPV, Meijer J, Tanck MWT, Dobritzsch D, Zoetekouw L, Dekkers LL, Roelofsen J, Meinsma R, Wymenga M, Kulik W, Büchel B, Hennekam RCM, Largiadèr CR. Kuilenburg ABPV, et al. Among authors: largiader cr. Biochim Biophys Acta. 2016 Apr;1862(4):754-762. doi: 10.1016/j.bbadis.2016.01.009. Epub 2016 Jan 12. Biochim Biophys Acta. 2016. PMID: 26804652 Free article.
Predicting 5-fluorouracil toxicity: DPD genotype and 5,6-dihydrouracil:uracil ratio.
Sistonen J, Büchel B, Froehlich TK, Kummer D, Fontana S, Joerger M, van Kuilenburg AB, Largiadèr CR. Sistonen J, et al. Among authors: largiader cr. Pharmacogenomics. 2014 Sep;15(13):1653-66. doi: 10.2217/pgs.14.126. Pharmacogenomics. 2014. PMID: 25410891
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