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2012 2
2013 1
2014 2
2016 1
2018 1
2020 1
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Page 1
Development of Kinase Inhibitors via Metal-Catalyzed C⁻H Arylation of 8-Alkyl-thiazolo[5,4-f]-quinazolin-9-ones Designed by Fragment-Growing Studies.
Couly F, Harari M, Dubouilh-Benard C, Bailly L, Petit E, Diharce J, Bonnet P, Meijer L, Fruit C, Besson T. Couly F, et al. Among authors: Dubouilh-Benard C. Molecules. 2018 Aug 29;23(9):2181. doi: 10.3390/molecules23092181. Molecules. 2018. PMID: 30158487 Free PMC article.
Design and synthesis of thiazolo[5,4-f]quinazolines as DYRK1A inhibitors, part II.
Foucourt A, Hédou D, Dubouilh-Benard C, Girard A, Taverne T, Casagrande AS, Désiré L, Leblond B, Besson T. Foucourt A, et al. Among authors: Dubouilh-Benard C. Molecules. 2014 Sep 26;19(10):15411-39. doi: 10.3390/molecules191015411. Molecules. 2014. PMID: 25264830 Free PMC article.
Design and synthesis of thiazolo[5,4-f]quinazolines as DYRK1A inhibitors, part I.
Foucourt A, Hédou D, Dubouilh-Benard C, Désiré L, Casagrande AS, Leblond B, Loäec N, Meijer L, Besson T. Foucourt A, et al. Among authors: Dubouilh-Benard C. Molecules. 2014 Sep 29;19(10):15546-71. doi: 10.3390/molecules191015546. Molecules. 2014. PMID: 25268714 Free PMC article.
Synthesis and biological evaluation of N-aryl-7-methoxybenzo[b]furo[3,2-d]pyrimidin-4-amines and their N-arylbenzo[b]thieno[3,2-d]pyrimidin-4-amine analogues as dual inhibitors of CLK1 and DYRK1A kinases.
Loidreau Y, Marchand P, Dubouilh-Benard C, Nourrisson MR, Duflos M, Loaëc N, Meijer L, Besson T. Loidreau Y, et al. Among authors: Dubouilh-Benard C. Eur J Med Chem. 2013 Jan;59:283-95. doi: 10.1016/j.ejmech.2012.11.030. Epub 2012 Nov 24. Eur J Med Chem. 2013. PMID: 23237976
Synthesis and biological evaluation of N-arylbenzo[b]thieno[3,2-d]pyrimidin-4-amines and their pyrido and pyrazino analogues as Ser/Thr kinase inhibitors.
Loidreau Y, Marchand P, Dubouilh-Benard C, Nourrisson MR, Duflos M, Lozach O, Loaëc N, Meijer L, Besson T. Loidreau Y, et al. Among authors: Dubouilh-Benard C. Eur J Med Chem. 2012 Dec;58:171-83. doi: 10.1016/j.ejmech.2012.10.006. Epub 2012 Oct 16. Eur J Med Chem. 2012. PMID: 23124214
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