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Leveraging the partition selection bias to achieve a high-quality clustering of mass spectra.

Silva ARF, Lima DB, Kurt LU, Dupré M, Chamot-Rooke J, Santos MDM, Nicolau CA, Valente RH, Barbosa VC, Carvalho PC. Silva ARF, et al. J Proteomics. 2021 Aug 15;245:104282. doi: 10.1016/j.jprot.2021.104282. Epub 2021 Jun 2. J Proteomics. 2021. PMID: 34089898

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TAK1 lessens the activity of the paracaspase MALT1 during T cell receptor signaling.

Nicolau CA, Gavard J, Bidère N. Nicolau CA, et al. Cell Immunol. 2020 Jul;353:104115. doi: 10.1016/j.cellimm.2020.104115. Epub 2020 Apr 28. Cell Immunol. 2020. PMID: 32388054

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Processing of Snake Venom Metalloproteinases: Generation of Toxin Diversity and Enzyme Inactivation.

Moura-da-Silva AM, Almeida MT, Portes-Junior JA, Nicolau CA, Gomes-Neto F, Valente RH. Moura-da-Silva AM, et al. Among authors: nicolau ca. Toxins (Basel). 2016 Jun 9;8(6):183. doi: 10.3390/toxins8060183. Toxins (Basel). 2016. PMID: 27294958 Free PMC article. Review.

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An in-depth snake venom proteopeptidome characterization: Benchmarking Bothrops jararaca.

Nicolau CA, Carvalho PC, Junqueira-de-Azevedo IL, Teixeira-Ferreira A, Junqueira M, Perales J, Neves-Ferreira AG, Valente RH. Nicolau CA, et al. J Proteomics. 2017 Jan 16;151:214-231. doi: 10.1016/j.jprot.2016.06.029. Epub 2016 Jun 30. J Proteomics. 2017. PMID: 27373870

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Molecular mechanisms underlying intraspecific variation in snake venom.

Amazonas DR, Portes-Junior JA, Nishiyama-Jr MY, Nicolau CA, Chalkidis HM, Mourão RHV, Grazziotin FG, Rokyta DR, Gibbs HL, Valente RH, Junqueira-de-Azevedo ILM, Moura-da-Silva AM. Amazonas DR, et al. Among authors: nicolau ca. J Proteomics. 2018 Jun 15;181:60-72. doi: 10.1016/j.jprot.2018.03.032. Epub 2018 Apr 3. J Proteomics. 2018. PMID: 29621647

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Revisiting the Therapeutic Potential of Bothrops jararaca Venom: Screening for Novel Activities Using Connectivity Mapping.

Nicolau CA, Prorock A, Bao Y, Neves-Ferreira AGDC, Valente RH, Fox JW. Nicolau CA, et al. Toxins (Basel). 2018 Feb 6;10(2):69. doi: 10.3390/toxins10020069. Toxins (Basel). 2018. PMID: 29415440 Free PMC article.

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Viperid Envenomation Wound Exudate Contributes to Increased Vascular Permeability via a DAMPs/TLR-4 Mediated Pathway.

Rucavado A, Nicolau CA, Escalante T, Kim J, Herrera C, Gutiérrez JM, Fox JW. Rucavado A, et al. Among authors: nicolau ca. Toxins (Basel). 2016 Nov 24;8(12):349. doi: 10.3390/toxins8120349. Toxins (Basel). 2016. PMID: 27886127 Free PMC article.

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Functional proteomic analyses of Bothrops atrox venom reveals phenotypes associated with habitat variation in the Amazon.

Sousa LF, Portes-Junior JA, Nicolau CA, Bernardoni JL, Nishiyama MY Jr, Amazonas DR, Freitas-de-Sousa LA, Mourão RH, Chalkidis HM, Valente RH, Moura-da-Silva AM. Sousa LF, et al. Among authors: nicolau ca. J Proteomics. 2017 Apr 21;159:32-46. doi: 10.1016/j.jprot.2017.03.003. Epub 2017 Mar 6. J Proteomics. 2017. PMID: 28274896

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Comparison of phylogeny, venom composition and neutralization by antivenom in diverse species of bothrops complex.

Sousa LF, Nicolau CA, Peixoto PS, Bernardoni JL, Oliveira SS, Portes-Junior JA, Mourão RH, Lima-dos-Santos I, Sano-Martins IS, Chalkidis HM, Valente RH, Moura-da-Silva AM. Sousa LF, et al. Among authors: nicolau ca. PLoS Negl Trop Dis. 2013 Sep 12;7(9):e2442. doi: 10.1371/journal.pntd.0002442. eCollection 2013. PLoS Negl Trop Dis. 2013. PMID: 24069493 Free PMC article.

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