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Genomic-scale prioritization of drug targets: the TDR Targets database.
Agüero F, Al-Lazikani B, Aslett M, Berriman M, Buckner FS, Campbell RK, Carmona S, Carruthers IM, Chan AW, Chen F, Crowther GJ, Doyle MA, Hertz-Fowler C, Hopkins AL, McAllister G, Nwaka S, Overington JP, Pain A, Paolini GV, Pieper U, Ralph SA, Riechers A, Roos DS, Sali A, Shanmugam D, Suzuki T, Van Voorhis WC, Verlinde CL. Agüero F, et al. Among authors: carruthers im. Nat Rev Drug Discov. 2008 Nov;7(11):900-7. doi: 10.1038/nrd2684. Epub 2008 Oct 17. Nat Rev Drug Discov. 2008. PMID: 18927591 Free PMC article. Review.
Rapid analysis of pharmacology for infectious diseases.
Hopkins AL, Bickerton GR, Carruthers IM, Boyer SK, Rubin H, Overington JP. Hopkins AL, et al. Among authors: carruthers im. Curr Top Med Chem. 2011;11(10):1292-300. doi: 10.2174/156802611795429130. Curr Top Med Chem. 2011. PMID: 21401504 Free PMC article. Review.
Application of RNAi to Genomic Drug Target Validation in Schistosomes.
Guidi A, Mansour NR, Paveley RA, Carruthers IM, Besnard J, Hopkins AL, Gilbert IH, Bickle QD. Guidi A, et al. Among authors: carruthers im. PLoS Negl Trop Dis. 2015 May 20;9(5):e0003801. doi: 10.1371/journal.pntd.0003801. eCollection 2015 May. PLoS Negl Trop Dis. 2015. PMID: 25992548 Free PMC article.