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Showing results for carsten gene rich
Your search for Carsten Gennerich retrieved no results
Oxidative Stress.
Sies H, Berndt C, Jones DP. Sies H, et al. Annu Rev Biochem. 2017 Jun 20;86:715-748. doi: 10.1146/annurev-biochem-061516-045037. Epub 2017 Apr 24. Annu Rev Biochem. 2017. PMID: 28441057 Review.
Chemokine-controlled NADPH oxidases and metabolically controlled mitochondrial sources of H(2)O(2) as well as glutathione- and thioredoxin-related pathways, with powerful enzymatic back-up systems, are responsible for fine-tuning physiological redox signaling. This makes for a …
Chemokine-controlled NADPH oxidases and metabolically controlled mitochondrial sources of H(2)O(2) as well as glutathione- and thioredoxin-r …
TLR2: cellular sensor for microbial and endogenous molecular patterns.
Kirschning CJ, Schumann RR. Kirschning CJ, et al. Curr Top Microbiol Immunol. 2002;270:121-44. doi: 10.1007/978-3-642-59430-4_8. Curr Top Microbiol Immunol. 2002. PMID: 12467248 Review.
The extracellular domain of the type I receptor molecule TLR2 contains 18 to 20 leucine rich repeat (LRR) and LRR like motives. The intracellular domain of TLR2 contains a Toll/IL-1 receptor/resistance protein typical TIR domain. ...
The extracellular domain of the type I receptor molecule TLR2 contains 18 to 20 leucine rich repeat (LRR) and LRR like motives. The i …
Visual analysis of biological data-knowledge networks.
Vehlow C, Kao DP, Bristow MR, Hunter LE, Weiskopf D, Görg C. Vehlow C, et al. BMC Bioinformatics. 2015 Apr 29;16:135. doi: 10.1186/s12859-015-0550-z. BMC Bioinformatics. 2015. PMID: 25925016 Free PMC article.
Biological networks that integrate experimental results with existing knowledge from biomedical databases and published literature can provide a rich resource and powerful basis for hypothesizing about mechanistic explanations for observed gene-phenotype relationshi …
Biological networks that integrate experimental results with existing knowledge from biomedical databases and published literature can provi …
Gut microbiota development during infancy: Impact of introducing allergenic foods.
Marrs T, Jo JH, Perkin MR, Rivett DW, Witney AA, Bruce KD, Logan K, Craven J, Radulovic S, Versteeg SA, van Ree R, McLean WHI, Strachan DP, Lack G, Kong HH, Flohr C. Marrs T, et al. J Allergy Clin Immunol. 2021 Feb;147(2):613-621.e9. doi: 10.1016/j.jaci.2020.09.042. J Allergy Clin Immunol. 2021. PMID: 33551026 Clinical Trial.
In this nested longitudinal study, fecal samples were collected at baseline, with additional sampling of selected cases and controls at 6 and 12 months to study the evolution of their gut microbiota, using 16S ribosomal RNA gene-targeted amplicon sequencing. RESULTS: In th …
In this nested longitudinal study, fecal samples were collected at baseline, with additional sampling of selected cases and controls at 6 an …
The RNA binding protein RBM38 (RNPC1) regulates splicing during late erythroid differentiation.
Heinicke LA, Nabet B, Shen S, Jiang P, van Zalen S, Cieply B, Russell JE, Xing Y, Carstens RP. Heinicke LA, et al. PLoS One. 2013 Oct 18;8(10):e78031. doi: 10.1371/journal.pone.0078031. eCollection 2013. PLoS One. 2013. PMID: 24250749 Free PMC article.
To further address the mechanism of RBM38-regulated alternative splicing, a novel mammalian protein expression system, followed by SELEX-Seq, was used to identify a GU-rich RBM38 binding motif. Lastly, using a tethering assay, we determined that RBM38 can directly activate …
To further address the mechanism of RBM38-regulated alternative splicing, a novel mammalian protein expression system, followed by SELEX-Seq …
Evidence for anaerobic oxidation of methane in sediments of a freshwater system (Lago di Cadagno).
Schubert CJ, Vazquez F, Lösekann-Behrens T, Knittel K, Tonolla M, Boetius A. Schubert CJ, et al. FEMS Microbiol Ecol. 2011 Apr;76(1):26-38. doi: 10.1111/j.1574-6941.2010.01036.x. Epub 2011 Jan 19. FEMS Microbiol Ecol. 2011. PMID: 21244447 Free article.
Anaerobic oxidation of methane (AOM) has been investigated in sediments of a high alpine sulfate-rich lake. Hot spots of AOM could be identified based on geochemical and isotopic evidence. ...Vienna Pee Dee Belemnite [VPDB]) of sedimentary carbonates at 16-20 cm sediment d …
Anaerobic oxidation of methane (AOM) has been investigated in sediments of a high alpine sulfate-rich lake. Hot spots of AOM could be …
Affinity chromatography using 2' fluoro-substituted RNAs for detection of RNA-protein interactions in RNase-rich or RNase-treated extracts.
Hovhannisyan R, Carstens R. Hovhannisyan R, et al. Biotechniques. 2009 Feb;46(2):95-8. doi: 10.2144/000113067. Biotechniques. 2009. PMID: 19317654 Free article.
Use of RNA affinity chromatography is commonly used to identify RNA binding proteins that interact with specific RNA cis-elements that function in post-transcriptional gene regulation. These purifications can be complicated by residual RNase activity in cellular extracts t …
Use of RNA affinity chromatography is commonly used to identify RNA binding proteins that interact with specific RNA cis-elements that funct …
The 3' untranslated region complex involved in stabilization of human alpha-globin mRNA assembles in the nucleus and serves an independent role as a splice enhancer.
Ji X, Kong J, Carstens RP, Liebhaber SA. Ji X, et al. Mol Cell Biol. 2007 May;27(9):3290-302. doi: 10.1128/MCB.02289-05. Epub 2007 Feb 26. Mol Cell Biol. 2007. PMID: 17325043 Free PMC article.
Consistent with this role, we find that alphaCP binds alpha-globin transcripts prior to splicing. Surprisingly, this binding occurs at C-rich sites within intron I as well as at the 3'UTR C-rich determinant. ...Linking nuclear and cytoplasmic controls by the action …
Consistent with this role, we find that alphaCP binds alpha-globin transcripts prior to splicing. Surprisingly, this binding occurs at C- …
Ten novel ORF15 mutations confirm mutational hot spot in the RPGR gene in European patients with X-linked retinitis pigmentosa.
Pusch CM, Broghammer M, Jurklies B, Besch D, Jacobi FK. Pusch CM, et al. Hum Mutat. 2002 Nov;20(5):405. doi: 10.1002/humu.9072. Hum Mutat. 2002. PMID: 12402343
RGPR was the first gene found to be mutated in XLRP, the subtype of RP displaying the most severe form of retinal degeneration with partial or complete blindness in the third or fourth decade of life. ...This discrepancy appeared to be resolved when Vervoort et al. identif …
RGPR was the first gene found to be mutated in XLRP, the subtype of RP displaying the most severe form of retinal degeneration with p …
Expression of the ELAV-like protein HuR is associated with higher tumor grade and increased cyclooxygenase-2 expression in human breast carcinoma.
Denkert C, Weichert W, Winzer KJ, Müller BM, Noske A, Niesporek S, Kristiansen G, Guski H, Dietel M, Hauptmann S. Denkert C, et al. Clin Cancer Res. 2004 Aug 15;10(16):5580-6. doi: 10.1158/1078-0432.CCR-04-0070. Clin Cancer Res. 2004. PMID: 15328200 Free article.
PURPOSE: The human ELAV (embryonic lethal abnormal vision)-like protein HuR stabilizes a certain group of cellular mRNAs that contain AU-rich elements in their 3'-untranslated region. Cell culture studies have shown that the mRNA of cyclooxygenase (COX)-2 can be stabilized …
PURPOSE: The human ELAV (embryonic lethal abnormal vision)-like protein HuR stabilizes a certain group of cellular mRNAs that contain AU- …
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