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Page 1
Cinobufagin induces FOXO1-regulated apoptosis, proliferation, migration, and invasion by inhibiting G9a in non-small-cell lung cancer A549 cells.
Zhang L, Liang B, Xu H, Gong Y, Hu W, Jin Z, Wu X, Chen X, Li M, Shi L, Shi Y, Wang Y, Yang L. Zhang L, et al. J Ethnopharmacol. 2022 Jun 12;291:115095. doi: 10.1016/j.jep.2022.115095. Epub 2022 Feb 15. J Ethnopharmacol. 2022. PMID: 35176466 Free article.
ETHNOPHARMACOLOGICAL RELEVANCE: Bufonis (VB), an animal drug called Chansu in China, is the product of the secretion of Bufo gargarizans Cantor or B. melanostictus Schneider. ...
ETHNOPHARMACOLOGICAL RELEVANCE: Bufonis (VB), an animal drug called Chansu in China, is the product of the secretion of Bufo gargariz …
Effects of methanol extract of Chansu on hypothalamic-pituitary-testis function in rats.
Wang SW, Lin H, Tsai SC, Hwu CM, Chiao YC, Lu CC, Chen JJ, Wang GJ, Chou CJ, Lin LC, Chen CF, Wang PS. Wang SW, et al. Metabolism. 1998 Oct;47(10):1211-6. doi: 10.1016/s0026-0495(98)90325-0. Metabolism. 1998. PMID: 9781623
Chansu, a galenical preparation of the dried white venom of Chinese Bufo bufo gargarizans, is one of the major components of Kyushin, a traditional Chinese medicine. ...Crude Chansu was extracted by methanol and purified by a Sep-Pak C18 column. ...
Chansu, a galenical preparation of the dried white venom of Chinese Bufo bufo gargarizans, is one of the major components of Kyushin, …
A target lipidomics approach to investigate the acute inflammatory irritation induced by indolealkylamines from Chansu water fraction in rats.
Yang X, Chen WY, Gong Y, DI LQ, Duan JA, Zhou J, Ma HY. Yang X, et al. Chin J Nat Med. 2021 Nov;19(11):856-867. doi: 10.1016/S1875-5364(21)60117-6. Chin J Nat Med. 2021. PMID: 34844724
Chansu has demonstrated adverse reactions in clinical settings, which is associated with its toxicity and limits its clinical applications. ...However, anti-inflammatory mediators from the CYP 450, ALA, and DHA pathways markedly decreased after exposure to Chansu wa …
Chansu has demonstrated adverse reactions in clinical settings, which is associated with its toxicity and limits its clinical applica …
Bufalin, a component in Chansu, inhibits proliferation and invasion of hepatocellular carcinoma cells.
Qiu DZ, Zhang ZJ, Wu WZ, Yang YK. Qiu DZ, et al. BMC Complement Altern Med. 2013 Jul 19;13:185. doi: 10.1186/1472-6882-13-185. BMC Complement Altern Med. 2013. PMID: 23870199 Free PMC article.
Bufalin, the major digoxin-like component of the traditional Chinese medicine Chansu, exhibits significant anti-tumor activities in many tumor cell lines. ...
Bufalin, the major digoxin-like component of the traditional Chinese medicine Chansu, exhibits significant anti-tumor activities in m …
Preparative isolation of bufalin and cinobufagin from Chinese traditional medicine ChanSu.
Yang Z, Luo H, Wang H, Hou H. Yang Z, et al. J Chromatogr Sci. 2008 Jan;46(1):81-5. doi: 10.1093/chromsci/46.1.81. J Chromatogr Sci. 2008. PMID: 18218193
In this investigation, a method is developed for the isolation and purification of bufadienolides (resibufogenin, cinobufagin, and bufalin) from the Chinese traditional medicine ChanSu. The crude ChanSu extract is prepared with solvent refluxing under optimal condit …
In this investigation, a method is developed for the isolation and purification of bufadienolides (resibufogenin, cinobufagin, and bufalin) …
Bufadienolides originated from toad source and their anti-inflammatory activity.
Zou D, Wang Q, Chen T, Sang D, Yang T, Wang Y, Gao M, He F, Li Y, He L, Longzhu D. Zou D, et al. Front Pharmacol. 2022 Oct 19;13:1044027. doi: 10.3389/fphar.2022.1044027. eCollection 2022. Front Pharmacol. 2022. PMID: 36339575 Free PMC article. Review.
As the predominantly active constituent in traditional Chinese medicine of Chansu, bufadienolide has been prescribed in the treatment of numerous ailments. ...
As the predominantly active constituent in traditional Chinese medicine of Chansu, bufadienolide has been prescribed in the treatment …
Telocinobufagin Has Antitumor Effects in Non-Small-Cell Lung Cancer by Inhibiting STAT3 Signaling.
Shen Y, Cai H, Ma S, Zhu W, Zhao H, Li J, Ye H, Yang L, Zhao C, Huang X, Xiao Z. Shen Y, et al. J Nat Prod. 2022 Apr 22;85(4):765-775. doi: 10.1021/acs.jnatprod.1c00761. Epub 2022 Feb 24. J Nat Prod. 2022. PMID: 35200033 Review.
Telocinobufagin, an active compound of the Chinese traditional medicine ChanSu, has antitumor effects, but its mechanism of action remains unknown. ...
Telocinobufagin, an active compound of the Chinese traditional medicine ChanSu, has antitumor effects, but its mechanism of action re …
Separation and determination of resibufogenin and cinobufagin in Chansu using reversed-phase liquid chromatography with gamma-cyclodextrin as mobile-phase modifier.
Xing J, Chen L, Song J, Guo C, Yang G, Zeng A. Xing J, et al. J Sep Sci. 2012 Aug;35(15):1884-92. doi: 10.1002/jssc.201200058. Epub 2012 May 24. J Sep Sci. 2012. PMID: 22623502
Finally, the optimized method was successfully applied to separate and determine of resibufogenin and cinobufagin in the different Chansu (Bufonis venenum) samples....
Finally, the optimized method was successfully applied to separate and determine of resibufogenin and cinobufagin in the different Chansu …
[Effects of Chansu injection on transplanting-tumor models S180 in mice and human colon cancer HT-29 in nude mice].
Yang ZH, Liang YJ, Guo JW, Pan JQ, Ding Y, Li GN. Yang ZH, et al. Zhonghua Wei Chang Wai Ke Za Zhi. 2005 Mar;8(2):169-71. Zhonghua Wei Chang Wai Ke Za Zhi. 2005. PMID: 16155834 Chinese.
OBJECTIVE: To study the antitumor effects of Chansu injection on transplanting- tumor of S(180 ) in mice and human colon cancer HT-29 in nude mice. ...No significant side effects were shown in the study group. CONCLUSIONS: Chansu injection can significantly inhibit …
OBJECTIVE: To study the antitumor effects of Chansu injection on transplanting- tumor of S(180 ) in mice and human colon cancer HT-29 …
49 results