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Did you mean chieh wen l (1 results)?
PIP4K2C inhibition reverses autophagic flux impairment induced by SARS-CoV-2.
Karim M, Mishra M, Lo CW, Saul S, Cagirici HB, Gourdelier M, Ghita L, Ojha A, Tran DHN, Agrawal A, McGraw C, East MP, Gammeltoft KA, Sahoo MK, Mooney NA, Johnson GL, Das S, Leyssen P, Neyts J, Chiu W, Cohen CA, Bukh J, Gottwein J, Dye JM, Neff N, Jackson PK, Pinsky BA, Laitinen T, Pantsar T, Poso A, Zanini F, De Jonghe S, Asquith CRM, Einav S. Karim M, et al. Among authors: lo cw. Nat Commun. 2025 Jul 10;16(1):6397. doi: 10.1038/s41467-025-61759-1. Nat Commun. 2025. PMID: 40640184 Free PMC article.
PIP4K2C inhibition reverses autophagic flux impairment induced by SARS-CoV-2.
Karim M, Mishra M, Lo CW, Saul S, Cagirici HB, Tran DHN, Agrawal A, Ghita L, Ojha A, East MP, Gammeltoft KA, Sahoo MK, Johnson GL, Das S, Jochmans D, Cohen CA, Gottwein J, Dye J, Neff N, Pinsky BA, Laitinen T, Pantsar T, Poso A, Zanini F, Jonghe S, Asquith CRM, Einav S. Karim M, et al. Among authors: lo cw. bioRxiv [Preprint]. 2024 Apr 17:2024.04.15.589676. doi: 10.1101/2024.04.15.589676. bioRxiv. 2024. Update in: Nat Commun. 2025 Jul 10;16(1):6397. doi: 10.1038/s41467-025-61759-1. PMID: 38659941 Free PMC article. Updated. Preprint.
Anticancer pan-ErbB inhibitors reduce inflammation and tissue injury and exert broad-spectrum antiviral effects.
Saul S, Karim M, Ghita L, Huang PT, Chiu W, Durán V, Lo CW, Kumar S, Bhalla N, Leyssen P, Alem F, Boghdeh NA, Tran DH, Cohen CA, Brown JA, Huie KE, Tindle C, Sibai M, Ye C, Khalil AM, Chiem K, Martinez-Sobrido L, Dye JM, Pinsky BA, Ghosh P, Das S, Solow-Cordero DE, Jin J, Wikswo JP, Jochmans D, Neyts J, De Jonghe S, Narayanan A, Einav S. Saul S, et al. Among authors: lo cw. J Clin Invest. 2023 Oct 2;133(19):e169510. doi: 10.1172/JCI169510. J Clin Invest. 2023. PMID: 37581931 Free PMC article.
An orally bioavailable SARS-CoV-2 main protease inhibitor exhibits improved affinity and reduced sensitivity to mutations.
Westberg M, Su Y, Zou X, Huang P, Rustagi A, Garhyan J, Patel PB, Fernandez D, Wu Y, Hao C, Lo CW, Karim M, Ning L, Beck A, Saenkham-Huntsinger P, Tat V, Drelich A, Peng BH, Einav S, Tseng CK, Blish C, Lin MZ. Westberg M, et al. Among authors: lo cw. Sci Transl Med. 2024 Mar 13;16(738):eadi0979. doi: 10.1126/scitranslmed.adi0979. Epub 2024 Mar 13. Sci Transl Med. 2024. PMID: 38478629 Free PMC article.
Numb-associated kinases are required for SARS-CoV-2 infection and are cellular targets for antiviral strategies.
Karim M, Saul S, Ghita L, Sahoo MK, Ye C, Bhalla N, Lo CW, Jin J, Park JG, Martinez-Gualda B, East MP, Johnson GL, Pinsky BA, Martinez-Sobrido L, Asquith CRM, Narayanan A, De Jonghe S, Einav S. Karim M, et al. Among authors: lo cw. Antiviral Res. 2022 Aug;204:105367. doi: 10.1016/j.antiviral.2022.105367. Epub 2022 Jun 20. Antiviral Res. 2022. PMID: 35738348 Free PMC article.
27 results