A human histidyl-tRNA synthetase splice variant therapeutic targets NRP2 to resolve lung inflammation and fibrosis.
Nangle LA, Xu Z, Siefker D, Burkart C, Chong YE, Zhai L, Geng Y, Polizzi C, Guy L, Eide L, Tong Y, Klopp-Savino S, Ferrer M, Rauch K, Wang A, Hamel K, Crampton S, Paz S, Chiang KP, Do MH, Burman L, Lee D, Zhang M, Ogilvie K, King D, Adams RA, Schimmel P.
Nangle LA, et al. Among authors: chong ye.
Sci Transl Med. 2025 Mar 12;17(789):eadp4754. doi: 10.1126/scitranslmed.adp4754. Epub 2025 Mar 12.
Sci Transl Med. 2025.
PMID: 40073151