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The mycotoxin beauvericin impairs development, fertility and life span in the nematode Caenorhabditis elegans accompanied by increased germ cell apoptosis and lipofuscin accumulation.

Büchter C, Koch K, Freyer M, Baier S, Saier C, Honnen S, Wätjen W. Büchter C, et al. Toxicol Lett. 2020 Nov 1;334:102-109. doi: 10.1016/j.toxlet.2020.09.016. Epub 2020 Sep 28. Toxicol Lett. 2020. PMID: 33002525

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Abyssinone V, a prenylated flavonoid isolated from the stem bark of Erythrina melanacantha increases oxidative stress and decreases stress resistance in Caenorhabditis elegans.

Koch K, Schulz G, Döring W, Büchter C, Havermann S, Mutiso PC, Passreiter C, Wätjen W. Koch K, et al. Among authors: buchter c. J Pharm Pharmacol. 2019 Jun;71(6):1007-1016. doi: 10.1111/jphp.13074. Epub 2019 Feb 21. J Pharm Pharmacol. 2019. PMID: 30793315

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Hibiscus sabdariffa L. extract prolongs lifespan and protects against amyloid-β toxicity in Caenorhabditis elegans: involvement of the FoxO and Nrf2 orthologues DAF-16 and SKN-1.

Koch K, Weldle N, Baier S, Büchter C, Wätjen W. Koch K, et al. Among authors: buchter c. Eur J Nutr. 2020 Feb;59(1):137-150. doi: 10.1007/s00394-019-01894-w. Epub 2019 Feb 1. Eur J Nutr. 2020. PMID: 30710163

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Polygonum multiflorum Extract Exerts Antioxidative Effects and Increases Life Span and Stress Resistance in the Model Organism Caenorhabditis elegans via DAF-16 and SIR-2.1.

Saier C, Büchter C, Koch K, Wätjen W. Saier C, et al. Among authors: buchter c. Plants (Basel). 2018 Jul 20;7(3):60. doi: 10.3390/plants7030060. Plants (Basel). 2018. PMID: 30036983 Free PMC article.

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Myricetin-mediated lifespan extension in Caenorhabditis elegans is modulated by DAF-16.

Büchter C, Ackermann D, Havermann S, Honnen S, Chovolou Y, Fritz G, Kampkötter A, Wätjen W. Büchter C, et al. Int J Mol Sci. 2013 Jun 4;14(6):11895-914. doi: 10.3390/ijms140611895. Int J Mol Sci. 2013. PMID: 23736695 Free PMC article.

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C. elegans VANG-1 modulates life span via insulin/IGF-1-like signaling.

Honnen SJ, Büchter C, Schröder V, Hoffmann M, Kohara Y, Kampkötter A, Bossinger O. Honnen SJ, et al. Among authors: buchter c. PLoS One. 2012;7(2):e32183. doi: 10.1371/journal.pone.0032183. Epub 2012 Feb 16. PLoS One. 2012. PMID: 22359667 Free PMC article.

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The resveratrol derivatives trans-3,5-dimethoxy-4-fluoro-4'-hydroxystilbene and trans-2,4',5-trihydroxystilbene decrease oxidative stress and prolong lifespan in Caenorhabditis elegans.

Fischer N, Büchter C, Koch K, Albert S, Csuk R, Wätjen W. Fischer N, et al. Among authors: buchter c. J Pharm Pharmacol. 2017 Jan;69(1):73-81. doi: 10.1111/jphp.12657. Epub 2016 Nov 23. J Pharm Pharmacol. 2017. PMID: 27882602 Free PMC article.

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The Lignan Pinoresinol Induces Nuclear Translocation of DAF-16 in Caenorhabditis elegans but has No Effect on Life Span.

Koch K, Büchter C, Havermann S, Wätjen W. Koch K, et al. Among authors: buchter c. Phytother Res. 2015 Jun;29(6):894-901. doi: 10.1002/ptr.5330. Epub 2015 Mar 31. Phytother Res. 2015. PMID: 25826281

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Caenorhabditis elegans as model system in pharmacology and toxicology: effects of flavonoids on redox-sensitive signalling pathways and ageing.

Koch K, Havermann S, Büchter C, Wätjen W. Koch K, et al. Among authors: buchter c. ScientificWorldJournal. 2014;2014:920398. doi: 10.1155/2014/920398. Epub 2014 Apr 30. ScientificWorldJournal. 2014. PMID: 24895670 Free PMC article.

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TSG (2,3,5,4'-Tetrahydroxystilbene-2-O- β -D-glucoside) from the Chinese Herb Polygonum multiflorum Increases Life Span and Stress Resistance of Caenorhabditis elegans.

Büchter C, Zhao L, Havermann S, Honnen S, Fritz G, Proksch P, Wätjen W. Büchter C, et al. Oxid Med Cell Longev. 2015;2015:124357. doi: 10.1155/2015/124357. Epub 2015 May 5. Oxid Med Cell Longev. 2015. PMID: 26075030 Free PMC article.

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