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2007 1
2008 1
2010 9
2014 3
2015 1
2016 2
2017 1
2020 3
2021 0
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Two phase 3 trials of bapineuzumab in mild-to-moderate Alzheimer's disease.
Salloway S, Sperling R, Fox NC, Blennow K, Klunk W, Raskind M, Sabbagh M, Honig LS, Porsteinsson AP, Ferris S, Reichert M, Ketter N, Nejadnik B, Guenzler V, Miloslavsky M, Wang D, Lu Y, Lull J, Tudor IC, Liu E, Grundman M, Yuen E, Black R, Brashear HR; Bapineuzumab 301 and 302 Clinical Trial Investigators. Salloway S, et al. N Engl J Med. 2014 Jan 23;370(4):322-33. doi: 10.1056/NEJMoa1304839. N Engl J Med. 2014. PMID: 24450891 Free PMC article. Clinical Trial.
BACKGROUND: Bapineuzumab, a humanized anti-amyloid-beta monoclonal antibody, is in clinical development for the treatment of Alzheimer's disease. METHODS: We conducted two double-blind, randomized, placebo-controlled, phase 3 trials involving patients with mild-to-moderate …
BACKGROUND: Bapineuzumab, a humanized anti-amyloid-beta monoclonal antibody, is in clinical development for the treatment of Alzheimer's
The world's major religions' points of view on end-of-life decisions in the intensive care unit.
Bülow HH, Sprung CL, Reinhart K, Prayag S, Du B, Armaganidis A, Abroug F, Levy MM. Bülow HH, et al. Intensive Care Med. 2008 Mar;34(3):423-30. doi: 10.1007/s00134-007-0973-8. Epub 2007 Dec 19. Intensive Care Med. 2008. PMID: 18157484 Review.
OBJECTIVE: Recent research has shown that the religious affiliation of both physicians and patients markedly influences end-of-life decisions in the intensive care unit in the Western world. The world's major religions' standings on withholding and withdrawing of therapy, …
OBJECTIVE: Recent research has shown that the religious affiliation of both physicians and patients markedly influences end-of-life decision …
Concerns over use of hydroxyethyl starch solutions.
Hartog CS, Natanson C, Sun J, Klein HG, Reinhart K. Hartog CS, et al. BMJ. 2014 Nov 10;349:g5981. doi: 10.1136/bmj.g5981. BMJ. 2014. PMID: 25385352 Free PMC article.
However, an EMA review last year permitted continued use in some patients, overturning an earlier decision to withdraw the product completely. Christiane Hartog and colleagues discuss the evidence and call on doctors to avoid using starch formulations...
However, an EMA review last year permitted continued use in some patients, overturning an earlier decision to withdraw the product completel …
Relatives' perception of stressors and psychological outcomes - Results from a survey study.
Matt B, Schwarzkopf D, Reinhart K, König C, Hartog CS. Matt B, et al. J Crit Care. 2017 Jun;39:172-177. doi: 10.1016/j.jcrc.2017.02.036. Epub 2017 Feb 27. J Crit Care. 2017. PMID: 28273613
The perception of being overburdened in the ICU predicted posttraumatic stress, anxiety and depression (all p0.001); In addition, patient's death or survival with significant deterioration in quality of life compared to status before admission predicted depression (p=0.016 …
The perception of being overburdened in the ICU predicted posttraumatic stress, anxiety and depression (all p0.001); In addition, patient' …
Sepsis 2016 Agra, India. Agra, India. 5-6 February 2016.
Sharma SK, Rohatgi A, Bajaj M, Sprung CL, Morales RC, Kasdan H, Reiter A, Volker T, Meissonnier J, Beloborodova N, Moroz V, Bedova A, Sarshor Y, Osipov A, Chernevskaya K, Fedotcheva N, Chernevskaya E, Beloborodova N, Imahase H, Yamada KC, Sakamoto Y, Ohta M, Sakurai R, Yahata M, Umeka M, Miike T, Koami H, Nagashima F, Iwamura T, Inoue S, Li Z, Grech D, Morcillo P, Bekker A, Ulloa L, Mukhopadhyay S, Pandey AD, Bhattacharjee S, Mohapatra SK, Wilson JK, Jadhav S, Misra RN, Gandham N, Angadi K, Vywahare C, Gupta N, Desai D, Bakochi A, Mohanty T, Linder A, Malmström J, Anand D, Bhargava S, Srivastava LM, Ray S, Fisher J, Bentzer P, Linder A, da Costa LHA, dos Santos Júnior NN, Catalão CHR, da Rocha MJA, Focà A, Peronace C, Matera G, Giancotti A, Barreca GS, Quirino A, Loria MT, Settembre P, Liberto MC, Amantea B, Hartog C, Moeller C, Fleischmann C, Thomas-Rueddel D, Vlasakov V, Rochwerg B, Theurer P, Reinhart K, Smith AE, Taylor SD, Da Costa C, Radford A, Lee T, Singer J, Boyd J, Fineberg D, Williams M, Russell JA. Sharma SK, et al. Crit Care. 2016 Mar 2;20 Suppl 1(Suppl 1):45. doi: 10.1186/s13054-016-1204-x. Crit Care. 2016. PMID: 26996981 Free PMC article.
Jane Fisher, Peter Bentzer, Adam Linder P13 Hypothalamic impairment is associated with vasopressin deficiency during sepsis Luis Henrique Angenendt da Costa, Nilton Nascimentos dos Santos Junior Carlos Henrique Rocha Catalao, Maria Jose Alves da Rocha P14 Presepsin (soluble CD14 …
Jane Fisher, Peter Bentzer, Adam Linder P13 Hypothalamic impairment is associated with vasopressin deficiency during sepsis Luis Henrique An …
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