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Synonymous Variants of Uncertain Silence.
Giacoletto CJ, Rotter JI, Grody WW, Schiller MR. Giacoletto CJ, et al. Int J Mol Sci. 2023 Jun 23;24(13):10556. doi: 10.3390/ijms241310556. Int J Mol Sci. 2023. PMID: 37445732 Free PMC article.
GigaAssay - An adaptable high-throughput saturation mutagenesis assay platform.
Benjamin R, Giacoletto CJ, FitzHugh ZT, Eames D, Buczek L, Wu X, Newsome J, Han MV, Pearson T, Wei Z, Banerjee A, Brown L, Valente LJ, Shen S, Deng HW, Schiller MR. Benjamin R, et al. Among authors: giacoletto cj. Genomics. 2022 Jul;114(4):110439. doi: 10.1016/j.ygeno.2022.110439. Epub 2022 Jul 26. Genomics. 2022. PMID: 35905834 Free PMC article.
Most synonymous allelic variants in HIV tat are not silent.
Giacoletto CJ, Benjamin R, Deng HW, Rotter JI, Schiller MR. Giacoletto CJ, et al. Genomics. 2023 May;115(3):110603. doi: 10.1016/j.ygeno.2023.110603. Epub 2023 Mar 7. Genomics. 2023. PMID: 36893872 Free PMC article.
Data supporting a saturation mutagenesis assay for Tat-driven transcription with the GigaAssay.
Benjamin R, Giacoletto CJ, FitzHugh ZT, Eames D, Buczek L, Wu X, Newsome J, Han MV, Pearson T, Wei Z, Banerjee A, Brown L, Valente LJ, Shen S, Deng HW, Schiller MR. Benjamin R, et al. Among authors: giacoletto cj. Data Brief. 2022 Sep 28;45:108641. doi: 10.1016/j.dib.2022.108641. eCollection 2022 Dec. Data Brief. 2022. PMID: 36426049 Free PMC article.
New Gain-of-Function Mutations Prioritize Mechanisms of HER2 Activation.
Giacoletto CJ, Valente LJ, Brown L, Patterson S, Gokhale R, Mockus SM, Grody WW, Deng HW, Rotter JI, Schiller MR. Giacoletto CJ, et al. medRxiv [Preprint]. 2025 Mar 4:2025.03.03.25323043. doi: 10.1101/2025.03.03.25323043. medRxiv. 2025. PMID: 40093211 Free PMC article. Preprint.