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Page 1
Synthesis and Antiviral Activity of Novel 1,3,4-Thiadiazole Inhibitors of DDX3X.
Brai A, Ronzini S, Riva V, Botta L, Zamperini C, Borgini M, Trivisani CI, Garbelli A, Pennisi C, Boccuto A, Saladini F, Zazzi M, Maga G, Botta M. Brai A, et al. Among authors: trivisani ci. Molecules. 2019 Nov 4;24(21):3988. doi: 10.3390/molecules24213988. Molecules. 2019. PMID: 31690062 Free PMC article.
Si113-prodrugs selectively activated by plasmin against hepatocellular and ovarian carcinoma.
Rango E, D'Antona L, Iovenitti G, Brai A, Mancini A, Zamperini C, Trivisani CI, Marianelli S, Fallacara AL, Molinari A, Cianciusi A, Schenone S, Perrotti N, Dreassi E, Botta M. Rango E, et al. Among authors: trivisani ci. Eur J Med Chem. 2021 Nov 5;223:113653. doi: 10.1016/j.ejmech.2021.113653. Epub 2021 Jun 17. Eur J Med Chem. 2021. PMID: 34161866
DDX3X inhibitors, an effective way to overcome HIV-1 resistance targeting host proteins.
Brai A, Riva V, Saladini F, Zamperini C, Trivisani CI, Garbelli A, Pennisi C, Giannini A, Boccuto A, Bugli F, Martini M, Sanguinetti M, Zazzi M, Dreassi E, Botta M, Maga G. Brai A, et al. Among authors: trivisani ci. Eur J Med Chem. 2020 Aug 15;200:112319. doi: 10.1016/j.ejmech.2020.112319. Epub 2020 May 7. Eur J Med Chem. 2020. PMID: 32446036 Free article.
Exploring the Implication of DDX3X in DENV Infection: Discovery of the First-in-Class DDX3X Fluorescent Inhibitor.
Brai A, Boccuto A, Monti M, Marchi S, Vicenti I, Saladini F, Trivisani CI, Pollutri A, Trombetta CM, Montomoli E, Riva V, Garbelli A, Nola EM, Zazzi M, Maga G, Dreassi E, Botta M. Brai A, et al. Among authors: trivisani ci. ACS Med Chem Lett. 2020 Apr 9;11(5):956-962. doi: 10.1021/acsmedchemlett.9b00681. eCollection 2020 May 14. ACS Med Chem Lett. 2020. PMID: 32435411 Free PMC article.
Targeting DDX3X Helicase Activity with BA103 Shows Promising Therapeutic Effects in Preclinical Glioblastoma Models.
Brai A, Riva V, Clementi L, Falsitta L, Zamperini C, Sinigiani V, Festuccia C, Sabetta S, Aiello D, Roselli C, Garbelli A, Trivisani CI, Maccari L, Bugli F, Sanguinetti M, Calandro P, Chiariello M, Quaranta P, Botta L, Angelucci A, Maga G, Botta M. Brai A, et al. Among authors: trivisani ci. Cancers (Basel). 2021 Nov 7;13(21):5569. doi: 10.3390/cancers13215569. Cancers (Basel). 2021. PMID: 34771731 Free PMC article.