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Discovery and Development of Inhibitors of the Plasmodial FNT-Type Lactate Transporter as Novel Antimalarials.
Pharmaceuticals (Basel). 2021 Nov 20;14(11):1191. doi: 10.3390/ph14111191.
Pharmaceuticals (Basel). 2021.
PMID: 34832972
Free PMC article.
Review.
The Plasmodium Lactate/H+ Transporter PfFNT Is Essential and Druggable In Vivo.
Davies H, Bergmann B, Walloch P, Nerlich C, Hansen C, Wittlin S, Spielmann T, Treeck M, Beitz E.
Davies H, et al. Among authors: nerlich c.
Antimicrob Agents Chemother. 2023 Aug 17;67(8):e0035623. doi: 10.1128/aac.00356-23. Epub 2023 Jul 10.
Antimicrob Agents Chemother. 2023.
PMID: 37428074
Free PMC article.
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Addressing the Intracellular Vestibule of the Plasmodial Lactate Transporter PfFNT by p-Substituted Inhibitors Amplifies In Vitro Activity.
Nerlich C, Tiedjens F, Hertel R, Henke B, Häuer S, Panitzsch LS, Hansen K, Franck O, Mete A, Leroy D, Schade D, Peifer C, Hannus S, Becker F, Wittlin S, Spielmann T, Beitz E.
Nerlich C, et al.
J Med Chem. 2024 Oct 3. doi: 10.1021/acs.jmedchem.4c01674. Online ahead of print.
J Med Chem. 2024.
PMID: 39361938
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