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A multi-platform approach to identify a blood-based host protein signature for distinguishing between bacterial and viral infections in febrile children (PERFORM): a multi-cohort machine learning study.
Jackson HR, Zandstra J, Menikou S, Hamilton MS, McArdle AJ, Fischer R, Thorne AM, Huang H, Tanck MW, Jansen MH, De T, Agyeman PKA, Von Both U, Carrol ED, Emonts M, Eleftheriou I, Van der Flier M, Fink C, Gloerich J, De Groot R, Moll HA, Pokorn M, Pollard AJ, Schlapbach LJ, Tsolia MN, Usuf E, Wright VJ, Yeung S, Zavadska D, Zenz W, Coin LJM, Casals-Pascual C, Cunnington AJ, Martinon-Torres F, Herberg JA, de Jonge MI, Levin M, Kuijpers TW, Kaforou M; PERFORM consortium. Jackson HR, et al. Lancet Digit Health. 2023 Nov;5(11):e774-e785. doi: 10.1016/S2589-7500(23)00149-8. Lancet Digit Health. 2023. PMID: 37890901 Free article.
Immunity to Streptococcus pyogenes and Common Respiratory Viruses at Age 0 to 4 Years After COVID-19 Restrictions.
Dokal K, Channon-Wells S, Davis C, Estrada-Rivadeneyra D, Huse KK, Lias A, Hamilton S, Guy RL, Lamagni T, Nichols S, Taylor A, Agyeman PKA, Anpananthar A, Basmaci R, Carrol ED, Carter MJ, De T, de Jonge MI, Emonts M, Elorrieta LE, Fidler K, Kolnik M, Kuijpers TW, Martinon-Torres F, Moll H, Mommert-Tripon M, Neshat S, Nyirenda-Nyang'wa M, O'Riordan S, Owens DR, Pathan N, Paulus S, Peters MJ, Pokorn M, Pollard AJ, Rivero-Calle I, Rojo P, Romani L, Rughani P, Schlapbach LJ, Schweintzger NA, Shen CF, Sulik A, Tsolia M, Usuf E, van der Flier M, Vermont C, von Both U, Wellman P, Wright VJ, Yeung S, Zavadska D, Cunnington AJ, Fink C, Herberg J, Kaforou M, Sriskandan S, Levin M, Parks T; PERFORM and DIAMONDS consortiums. Dokal K, et al. JAMA Netw Open. 2025 Oct 1;8(10):e2537808. doi: 10.1001/jamanetworkopen.2025.37808. JAMA Netw Open. 2025. PMID: 41091464 Free PMC article.
Predicting trajectories of illness using RNA velocity of whole blood.
Dunican C, Wilson C, Habgood-Coote D, Paterson S, Noursadeghi M, Moseki R, Stek C, Wilkinson RJ, Agyeman PKA, Beudeker CR, Biesbroek G, von Both U, Brengel-Pesce K, Carrol ED, Coin LJM, D'Souza G, De T, Emonts M, Fidler K, Fink CG, van der Flier M, Georgaki I, Kolberg L, Kolnik M, Kuijpers T, Martinón-Torres F, Mommert-Tripon M, Nichols S, Paulus S, Pokorn M, Pollard AJ, Rivero-Calle I, Rudzate A, Schlapbach LJ, Schweintzger NA, Shen CF, Shrestha S, Tan CD, Tsolia M, Usuf E, van der Velden F, Vermont CL, Voice M, Yeung S, Zavadska D, Zenz W, Wright VJ, Levin M, Herberg J; PERFORM Consortium; Lai RPJ, Meintjes G, Chiu C, Barahona M, Kaforou M, Cunnington AJ. Dunican C, et al. Nat Commun. 2026 May 6;17(1):3652. doi: 10.1038/s41467-026-71685-5. Nat Commun. 2026. PMID: 42091589 Free PMC article.
Procalcitonin use in febrile children attending European emergency departments: a prospective multicenter study.
Borensztajn DM, Zachariasse JM, Carrol ED, Nijman RG, von Both U, Emonts M, Herberg J, Kohlmaier B, Levin M, Lim E, Maconochie IK, Martinón-Torres F, Pokorn M, Rivero-Calle I, Rudzāte A, Tan CD, Tsolia M, Vermont C, Zavadska D, Zenz W, Moll HA; PERFORM consortium: Personalised Risk assessment in febrile children to optimise Real-life Management across the European Union. Borensztajn DM, et al. BMC Pediatr. 2025 Mar 1;25(1):157. doi: 10.1186/s12887-025-05483-1. BMC Pediatr. 2025. PMID: 40025449 Free PMC article.
Pharmacokinetics and Safety of Ceftobiprole in Pediatric Patients.
Rubino CM, Polak M, Schröpf S, Münch HG, Smits A, Cossey V, Tomasik T, Kwinta P, Snariene R, Liubsys A, Gardovska D, Hornik CD, Bosheva M, Ruehle C, Litherland K, Hamed K. Rubino CM, et al. Among authors: gardovska d. Pediatr Infect Dis J. 2021 Nov 1;40(11):997-1003. doi: 10.1097/INF.0000000000003296. Pediatr Infect Dis J. 2021. PMID: 34533489 Free PMC article. Clinical Trial.
Correction to: Febrile illness in high-risk children: a prospective, international observational study.
van der Velden FJS, de Vries G, Martin A, Lim E, von Both U, Kolberg L, Carrol ED, Khanijau A, Herberg JA, De T, Galassini R, Kuijpers TW, Martinón-Torres F, Rivero-Calle I, Vermont CL, Hagedoorn NN, Pokorn M, Pollard AJ, Schlapbach LJ, Tsolia M, Elefhteriou I, Yeung S, Zavadska D, Fink C, Voice M, Zenz W, Kohlmaier B, Agyeman PKA, Usuf E, Secka F, de Groot R, Levin M, van der Flier M, Emonts M; PERFORM consortium. van der Velden FJS, et al. Eur J Pediatr. 2023 Feb;182(2):555-556. doi: 10.1007/s00431-022-04788-y. Eur J Pediatr. 2023. PMID: 36689005 Free PMC article. No abstract available.
Febrile illness in high-risk children: a prospective, international observational study.
van der Velden FJS, de Vries G, Martin A, Lim E, von Both U, Kolberg L, Carrol ED, Khanijau A, Herberg JA, De T, Galassini R, Kuijpers TW, Martinón-Torres F, Rivero-Calle I, Vermont CL, Hagedoorn NN, Pokorn M, Pollard AJ, Schlapbach LJ, Tsolia M, Elefhteriou I, Yeung S, Zavadska D, Fink C, Voice M, Zenz W, Kohlmaier B, Agyeman PKA, Usuf E, Secka F, de Groot R, Levin M, van der Flier M, Emonts M; PERFORM consortium. van der Velden FJS, et al. Eur J Pediatr. 2023 Feb;182(2):543-554. doi: 10.1007/s00431-022-04642-1. Epub 2022 Oct 15. Eur J Pediatr. 2023. PMID: 36243780 Free PMC article.
Impact of infection on proteome-wide glycosylation revealed by distinct signatures for bacterial and viral pathogens.
Willems E, Gloerich J, Suppers A, van der Flier M, van den Heuvel LP, van de Kar N, Philipsen RHLA, van Dael M, Kaforou M, Wright VJ, Herberg JA, Torres FM, Levin M, de Groot R, van Gool AJ, Lefeber DJ, Wessels HJCT, de Jonge MI; PERFORM consortium. Willems E, et al. iScience. 2023 Jul 4;26(8):107257. doi: 10.1016/j.isci.2023.107257. eCollection 2023 Aug 18. iScience. 2023. PMID: 37520696 Free PMC article.
48 results