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The new 6q27 tumor suppressor DACT2, frequently silenced by CpG methylation, sensitizes nasopharyngeal cancer cells to paclitaxel and 5-FU toxicity via β-catenin/Cdc25c signaling and G2/M arrest.
Zhang Y, Fan J, Fan Y, Li L, He X, Xiang Q, Mu J, Zhou D, Sun X, Yang Y, Ren G, Tao Q, Xiang T. Zhang Y, et al. Among authors: zhou d. Clin Epigenetics. 2018 Feb 27;10(1):26. doi: 10.1186/s13148-018-0459-2. Clin Epigenetics. 2018. PMID: 30359298 Free PMC article.
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