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Psychedelic effects of psilocybin correlate with serotonin 2A receptor occupancy and plasma psilocin levels.
Madsen MK, Fisher PM, Burmester D, Dyssegaard A, Stenbæk DS, Kristiansen S, Johansen SS, Lehel S, Linnet K, Svarer C, Erritzoe D, Ozenne B, Knudsen GM. Madsen MK, et al. Among authors: burmester d. Neuropsychopharmacology. 2019 Jun;44(7):1328-1334. doi: 10.1038/s41386-019-0324-9. Epub 2019 Jan 26. Neuropsychopharmacology. 2019. PMID: 30685771 Free PMC article.
A single psilocybin dose is associated with long-term increased mindfulness, preceded by a proportional change in neocortical 5-HT2A receptor binding.
Madsen MK, Fisher PM, Stenbæk DS, Kristiansen S, Burmester D, Lehel S, Páleníček T, Kuchař M, Svarer C, Ozenne B, Knudsen GM. Madsen MK, et al. Among authors: burmester d. Eur Neuropsychopharmacol. 2020 Apr;33:71-80. doi: 10.1016/j.euroneuro.2020.02.001. Epub 2020 Mar 4. Eur Neuropsychopharmacol. 2020. PMID: 32146028