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Discovery of Protein Modifications Using Differential Tandem Mass Spectrometry Proteomics.

Cifani P, Li Z, Luo D, Grivainis M, Intlekofer AM, Fenyö D, Kentsis A. Cifani P, et al. Among authors: luo d. J Proteome Res. 2021 Apr 2;20(4):1835-1848. doi: 10.1021/acs.jproteome.0c00638. Epub 2021 Mar 22. J Proteome Res. 2021. PMID: 33749263 Free PMC article.

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Advances in exploring the therapeutic potential of marine natural products.

Liang X, Luo D, Luesch H. Liang X, et al. Among authors: luo d. Pharmacol Res. 2019 Sep;147:104373. doi: 10.1016/j.phrs.2019.104373. Epub 2019 Jul 25. Pharmacol Res. 2019. PMID: 31351913 Free PMC article. Review.

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Discovery of Amantamide, a Selective CXCR7 Agonist from Marine Cyanobacteria.

Liang X, Luo D, Yan JL, Rezaei MA, Salvador-Reyes LA, Gunasekera SP, Li C, Ye T, Paul VJ, Luesch H. Liang X, et al. Among authors: luo d. Org Lett. 2019 Mar 15;21(6):1622-1626. doi: 10.1021/acs.orglett.9b00163. Epub 2019 Feb 19. Org Lett. 2019. PMID: 30779584 Free PMC article.

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Genomic and Targeted Approaches Unveil the Cell Membrane as a Major Target of the Antifungal Cytotoxin Amantelide A.

Elsadek LA, Matthews JH, Nishimura S, Nakatani T, Ito A, Gu T, Luo D, Salvador-Reyes LA, Paul VJ, Kakeya H, Luesch H. Elsadek LA, et al. Among authors: luo d. Chembiochem. 2021 May 14;22(10):1790-1799. doi: 10.1002/cbic.202000685. Epub 2021 Mar 23. Chembiochem. 2021. PMID: 33527693 Free PMC article.

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Tutuilamides A-C: Vinyl-Chloride-Containing Cyclodepsipeptides from Marine Cyanobacteria with Potent Elastase Inhibitory Properties.

Keller L, Canuto KM, Liu C, Suzuki BM, Almaliti J, Sikandar A, Naman CB, Glukhov E, Luo D, Duggan BM, Luesch H, Koehnke J, O'Donoghue AJ, Gerwick WH. Keller L, et al. Among authors: luo d. ACS Chem Biol. 2020 Mar 20;15(3):751-757. doi: 10.1021/acschembio.9b00992. Epub 2020 Jan 28. ACS Chem Biol. 2020. PMID: 31935054 Free PMC article.

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Ahp-Cyclodepsipeptide Inhibitors of Elastase: Lyngbyastatin 7 Stability, Scalable Synthesis, and Focused Library Analysis.

Luo D, Luesch H. Luo D, et al. ACS Med Chem Lett. 2020 Mar 4;11(4):419-425. doi: 10.1021/acsmedchemlett.9b00473. eCollection 2020 Apr 9. ACS Med Chem Lett. 2020. PMID: 32292544 Free PMC article.

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Discovery of deoxylimonin δ-lactam derivative with favorable anti-inflammation and antinociception efficacy from chemical modified limonin/deoxylimonin analogs.

Wang S, Han X, Yang Y, Zhou C, Luo D, He W, Zhu Q, Xu Y. Wang S, et al. Among authors: luo d. Bioorg Chem. 2020 Jul;100:103886. doi: 10.1016/j.bioorg.2020.103886. Epub 2020 Apr 24. Bioorg Chem. 2020. PMID: 32371249

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A dive into membrane dynamics with sponge peptides.

Luo D, Luesch H. Luo D, et al. Chem Biol. 2015 May 21;22(5):565-7. doi: 10.1016/j.chembiol.2015.05.003. Chem Biol. 2015. PMID: 26000744

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Ahp-Cyclodepsipeptides as tunable inhibitors of human neutrophil elastase and kallikrein 7: Total synthesis of tutuilamide A, serine protease selectivity profile and comparison with lyngbyastatin 7.

Chen QY, Luo D, Seabra GM, Luesch H. Chen QY, et al. Among authors: luo d. Bioorg Med Chem. 2020 Dec 1;28(23):115756. doi: 10.1016/j.bmc.2020.115756. Epub 2020 Sep 9. Bioorg Med Chem. 2020. PMID: 33002682 Free PMC article.

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Isolation, Structure Elucidation and Biological Evaluation of Lagunamide D: A New Cytotoxic Macrocyclic Depsipeptide from Marine Cyanobacteria.

Luo D, Putra MY, Ye T, Paul VJ, Luesch H. Luo D, et al. Mar Drugs. 2019 Feb 1;17(2):83. doi: 10.3390/md17020083. Mar Drugs. 2019. PMID: 30717076 Free PMC article.

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