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Are the Hydantoin-1,3,5-triazine 5-HT6R Ligands a Hope to a Find New Procognitive and Anti-Obesity Drug? Considerations Based on Primary In Vivo Assays and ADME-Tox Profile In Vitro.
Lubelska A, Latacz G, Jastrzębska-Więsek M, Kotańska M, Kurczab R, Partyka A, Marć MA, Wilczyńska D, Doroz-Płonka A, Łażewska D, Wesołowska A, Kieć-Kononowicz K, Handzlik J. Lubelska A, et al. Among authors: Wilczynska D. Molecules. 2019 Dec 6;24(24):4472. doi: 10.3390/molecules24244472. Molecules. 2019. PMID: 31817628 Free PMC article.
The 1,3,5-Triazine Derivatives as Innovative Chemical Family of 5-HT6 Serotonin Receptor Agents with Therapeutic Perspectives for Cognitive Impairment.
Latacz G, Lubelska A, Jastrzębska-Więsek M, Partyka A, Marć MA, Satała G, Wilczyńska D, Kotańska M, Więcek M, Kamińska K, Wesołowska A, Kieć-Kononowicz K, Handzlik J. Latacz G, et al. Among authors: Wilczynska D. Int J Mol Sci. 2019 Jul 12;20(14):3420. doi: 10.3390/ijms20143420. Int J Mol Sci. 2019. PMID: 31336820 Free PMC article.
Novel Aryloxyethyl Derivatives of 1-(1-Benzoylpiperidin-4-yl)methanamine as the Extracellular Regulated Kinases 1/2 (ERK1/2) Phosphorylation-Preferring Serotonin 5-HT1A Receptor-Biased Agonists with Robust Antidepressant-like Activity.
Sniecikowska J, Gluch-Lutwin M, Bucki A, Więckowska A, Siwek A, Jastrzebska-Wiesek M, Partyka A, Wilczyńska D, Pytka K, Pociecha K, Cios A, Wyska E, Wesołowska A, Pawłowski M, Varney MA, Newman-Tancredi A, Kolaczkowski M. Sniecikowska J, et al. Among authors: Wilczynska D. J Med Chem. 2019 Mar 14;62(5):2750-2771. doi: 10.1021/acs.jmedchem.9b00062. Epub 2019 Mar 2. J Med Chem. 2019. PMID: 30721053
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