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Very-low-carbohydrate diet enhances human T-cell immunity through immunometabolic reprogramming.

Hirschberger S, Strauß G, Effinger D, Marstaller X, Ferstl A, Müller MB, Wu T, Hübner M, Rahmel T, Mascolo H, Exner N, Heß J, Kreth FW, Unger K, Kreth S. Hirschberger S, et al. Among authors: effinger d. EMBO Mol Med. 2021 Aug 9;13(8):e14323. doi: 10.15252/emmm.202114323. Epub 2021 Jun 21. EMBO Mol Med. 2021. PMID: 34151532 Free PMC article.

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MicroRNA-93 acts as an "anti-inflammatory tumor suppressor" in glioblastoma.

Hübner M, Moellhoff N, Effinger D, Hinske CL, Hirschberger S, Wu T, Müller MB, Strauß G, Kreth FW, Kreth S. Hübner M, et al. Among authors: effinger d. Neurooncol Adv. 2020 Apr 18;2(1):vdaa047. doi: 10.1093/noajnl/vdaa047. eCollection 2020 Jan-Dec. Neurooncol Adv. 2020. PMID: 32642700 Free PMC article.

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Myeloid-Derived Suppressor Cells Mediate Immunosuppression After Cardiopulmonary Bypass.

Hübner M, Tomasi R, Effinger D, Wu T, Klein G, Bender M, Kilger E, Juchem G, Schwedhelm E, Kreth S. Hübner M, et al. Among authors: effinger d. Crit Care Med. 2019 Aug;47(8):e700-e709. doi: 10.1097/CCM.0000000000003820. Crit Care Med. 2019. PMID: 31149961

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The IL-1 Antagonist Anakinra Attenuates Glioblastoma Aggressiveness by Dampening Tumor-Associated Inflammation.

Hübner M, Effinger D, Wu T, Strauß G, Pogoda K, Kreth FW, Kreth S. Hübner M, et al. Among authors: effinger d. Cancers (Basel). 2020 Feb 13;12(2):433. doi: 10.3390/cancers12020433. Cancers (Basel). 2020. PMID: 32069807 Free PMC article.

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Impact of carbohydrate-reduced nutrition in septic patients on ICU: study protocol for a prospective randomised controlled trial.

Rahmel T, Hübner M, Koos B, Wolf A, Willemsen KM, Strauß G, Effinger D, Adamzik M, Kreth S. Rahmel T, et al. Among authors: effinger d. BMJ Open. 2020 Jul 8;10(7):e038532. doi: 10.1136/bmjopen-2020-038532. BMJ Open. 2020. PMID: 32641340 Free PMC article.

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Intronic miR-744 Inhibits Glioblastoma Migration by Functionally Antagonizing Its Host Gene MAP2K4.

Hübner M, Hinske CL, Effinger D, Wu T, Thon N, Kreth FW, Kreth S. Hübner M, et al. Among authors: effinger d. Cancers (Basel). 2018 Oct 25;10(11):400. doi: 10.3390/cancers10110400. Cancers (Basel). 2018. PMID: 30366472 Free PMC article.

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Identification of suitable controls for miRNA quantification in T-cells and whole blood cells in sepsis.

Hirschberger S, Hübner M, Strauß G, Effinger D, Bauer M, Weis S, Giamarellos-Bourboulis EJ, Kreth S. Hirschberger S, et al. Among authors: effinger d. Sci Rep. 2019 Oct 31;9(1):15735. doi: 10.1038/s41598-019-51782-w. Sci Rep. 2019. PMID: 31672997 Free PMC article.

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Ketone Bodies Improve Human CD8⁺ Cytotoxic T-Cell Immune Response During COVID-19 Infection.

Hirschberger S, Gellert L, Effinger D, Muenchhoff M, Herrmann M, Briegel JM, Zwißler B, Kreth S. Hirschberger S, et al. Among authors: effinger d. Front Med (Lausanne). 2022 Jun 16;9:923502. doi: 10.3389/fmed.2022.923502. eCollection 2022. Front Med (Lausanne). 2022. PMID: 35783654 Free PMC article.

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Cell-Crossing Functional Network Driven by microRNA-125a Regulates Endothelial Permeability and Monocyte Trafficking in Acute Inflammation.

Müller MB, Hübner M, Li L, Tomasi S, Ließke V, Effinger D, Hirschberger S, Pogoda K, Sperandio M, Kreth S. Müller MB, et al. Among authors: effinger d. Front Immunol. 2022 Mar 24;13:826047. doi: 10.3389/fimmu.2022.826047. eCollection 2022. Front Immunol. 2022. PMID: 35401562 Free PMC article.

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