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DNA-damaging steroidal alkaloids from Eclipta alba from the suriname rainforest1.
Abdel-Kader MS, Bahler BD, Malone S, Werkhoven MC, van Troon F, David, Wisse JH, Bursuker I, Neddermann KM, Mamber SW, Kingston DG. Abdel-Kader MS, et al. J Nat Prod. 1998 Oct;61(10):1202-8. doi: 10.1021/np970561c. J Nat Prod. 1998. PMID: 9784152
The major alkaloid was identified as (20S)(25S)-22,26-imino-cholesta-5,22(N)-dien-3beta-ol (verazine, 3), while the new alkaloids were identified as 20-epi-3-dehydroxy-3-oxo-5,6-dihydro-4,5-dehydroverazine (1), ecliptalbine [(20R)-20-pyridyl-cholesta-5-ene-3beta,23-diol] ( …
The major alkaloid was identified as (20S)(25S)-22,26-imino-cholesta-5,22(N)-dien-3beta-ol (verazine, 3), while the new alkaloids were ident …