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1

Influenza Virus Infection, Interferon Response, Viral Counter-Response, and Apoptosis.

Shim JM, Kim J, Tenson T, Min JY, Kainov DE. Shim JM, et al. Among authors: Kainov DE. Viruses. 2017 Aug 12;9(8):223. doi: 10.3390/v9080223. Viruses. 2017. PMID: 28805681 Free PMC article. Review.

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2

Antiviral Properties of Chemical Inhibitors of Cellular Anti-Apoptotic Bcl-2 Proteins.

Bulanova D, Ianevski A, Bugai A, Akimov Y, Kuivanen S, Paavilainen H, Kakkola L, Nandania J, Turunen L, Ohman T, Ala-Hongisto H, Pesonen HM, Kuisma MS, Honkimaa A, Walton EL, Oksenych V, Lorey MB, Guschin D, Shim J, Kim J, Than TT, Chang SY, Hukkanen V, Kulesskiy E, Marjomaki VS, Julkunen I, Nyman TA, Matikainen S, Saarela JS, Sane F, Hober D, Gabriel G, De Brabander JK, Martikainen M, Windisch MP, Min JY, Bruzzone R, Aittokallio T, Vähä-Koskela M, Vapalahti O, Pulk A, Velagapudi V, Kainov DE. Bulanova D, et al. Among authors: Kainov DE. Viruses. 2017 Sep 25;9(10):271. doi: 10.3390/v9100271. Viruses. 2017. PMID: 28946654 Free PMC article.

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3

Multi-Omics Studies towards Novel Modulators of Influenza A Virus-Host Interaction.

Söderholm S, Fu Y, Gaelings L, Belanov S, Yetukuri L, Berlinkov M, Cheltsov AV, Anders S, Aittokallio T, Nyman TA, Matikainen S, Kainov DE. Söderholm S, et al. Among authors: Kainov DE. Viruses. 2016 Sep 29;8(10):269. doi: 10.3390/v8100269. Viruses. 2016. PMID: 27690086 Free PMC article. Review.

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4

Regulation of kynurenine biosynthesis during influenza virus infection.

Gaelings L, Söderholm S, Bugai A, Fu Y, Nandania J, Schepens B, Lorey MB, Tynell J, Vande Ginste L, Le Goffic R, Miller MS, Kuisma M, Marjomäki V, De Brabander J, Matikainen S, Nyman TA, Bamford DH, Saelens X, Julkunen I, Paavilainen H, Hukkanen V, Velagapudi V, Kainov DE. Gaelings L, et al. Among authors: Kainov DE. FEBS J. 2017 Jan;284(2):222-236. doi: 10.1111/febs.13966. Epub 2016 Dec 14. FEBS J. 2017. PMID: 27860276 Free article.

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5

A Systems Approach to Study Immuno- and Neuro-Modulatory Properties of Antiviral Agents.

Zusinaite E, Ianevski A, Niukkanen D, Poranen MM, Bjørås M, Afset JE, Tenson T, Velagapudi V, Merits A, Kainov DE. Zusinaite E, et al. Among authors: Kainov DE. Viruses. 2018 Aug 12;10(8):423. doi: 10.3390/v10080423. Viruses. 2018. PMID: 30103549 Free PMC article. Review.

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6

JNJ872 inhibits influenza A virus replication without altering cellular antiviral responses.

Fu Y, Gaelings L, Söderholm S, Belanov S, Nandania J, Nyman TA, Matikainen S, Anders S, Velagapudi V, Kainov DE. Fu Y, et al. Among authors: Kainov DE. Antiviral Res. 2016 Sep;133:23-31. doi: 10.1016/j.antiviral.2016.07.008. Epub 2016 Jul 20. Antiviral Res. 2016. PMID: 27451344

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7

Obatoclax, saliphenylhalamide and gemcitabine inhibit Zika virus infection in vitro and differentially affect cellular signaling, transcription and metabolism.

Kuivanen S, Bespalov MM, Nandania J, Ianevski A, Velagapudi V, De Brabander JK, Kainov DE, Vapalahti O. Kuivanen S, et al. Among authors: Kainov DE. Antiviral Res. 2017 Mar;139:117-128. doi: 10.1016/j.antiviral.2016.12.022. Epub 2016 Dec 31. Antiviral Res. 2017. PMID: 28049006

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8

Influenza virus NS1 protein binds cellular DNA to block transcription of antiviral genes.

Anastasina M, Le May N, Bugai A, Fu Y, Söderholm S, Gaelings L, Ohman T, Tynell J, Kyttänen S, Barboric M, Nyman TA, Matikainen S, Julkunen I, Butcher SJ, Egly JM, Kainov DE. Anastasina M, et al. Among authors: Kainov DE. Biochim Biophys Acta. 2016 Nov;1859(11):1440-1448. doi: 10.1016/j.bbagrm.2016.09.005. Epub 2016 Sep 21. Biochim Biophys Acta. 2016. PMID: 27664935

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9

Single Passage of Human Metapneumovirus in LLC-MK2 Cells Does Not Affect Viral Protein-Coding Capacity.

Loevenich S, Ianevski A, Oitmaa E, Kainov DE, Anthonsen MW. Loevenich S, et al. Among authors: Kainov DE. Genome Announc. 2018 May 24;6(21):e00440-18. doi: 10.1128/genomeA.00440-18. Genome Announc. 2018. PMID: 29798923 Free PMC article.

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10

Phosphoproteomics to Characterize Host Response During Influenza A Virus Infection of Human Macrophages.

Söderholm S, Kainov DE, Öhman T, Denisova OV, Schepens B, Kulesskiy E, Imanishi SY, Corthals G, Hintsanen P, Aittokallio T, Saelens X, Matikainen S, Nyman TA. Söderholm S, et al. Among authors: Kainov DE. Mol Cell Proteomics. 2016 Oct;15(10):3203-3219. doi: 10.1074/mcp.M116.057984. Epub 2016 Aug 2. Mol Cell Proteomics. 2016. PMID: 27486199 Free PMC article.

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