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13-Weeks subchronic toxicity of isoquercitrin-γ-cyclodextrin (IQC-γCD) molecular inclusion complex in Sprague-Dawley rats.

Kapoor MP, Moriwaki M, Timm D, Yamagata H, Maruyama G, Nisihara Y, Nakazawa T, Takata S, Nakamura D. Kapoor MP, et al. Among authors: timm d. Food Chem Toxicol. 2021 Jun;152:112217. doi: 10.1016/j.fct.2021.112217. Epub 2021 Apr 15. Food Chem Toxicol. 2021. PMID: 33865935 Free article.

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Green Tea Catechin Association with Ultraviolet Radiation-Induced Erythema: A Systematic Review and Meta-Analysis.

Kapoor MP, Sugita M, Fukuzawa Y, Timm D, Ozeki M, Okubo T. Kapoor MP, et al. Among authors: timm d. Molecules. 2021 Jun 17;26(12):3702. doi: 10.3390/molecules26123702. Molecules. 2021. PMID: 34204433 Free PMC article.

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Clinical evaluation of Emblica Officinalis Gatertn (Amla) in healthy human subjects: Health benefits and safety results from a randomized, double-blind, crossover placebo-controlled study.

Kapoor MP, Suzuki K, Derek T, Ozeki M, Okubo T. Kapoor MP, et al. Among authors: derek t. Contemp Clin Trials Commun. 2019 Nov 27;17:100499. doi: 10.1016/j.conctc.2019.100499. eCollection 2020 Mar. Contemp Clin Trials Commun. 2019. PMID: 31890983 Free PMC article.

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Gene Therapy Corrects Brain and Behavioral Pathologies in CLN6-Batten Disease.

Cain JT, Likhite S, White KA, Timm DJ, Davis SS, Johnson TB, Dennys-Rivers CN, Rinaldi F, Motti D, Corcoran S, Morales P, Pierson C, Hughes SM, Lee SY, Kaspar BK, Meyer K, Weimer JM. Cain JT, et al. Among authors: timm dj. Mol Ther. 2019 Oct 2;27(10):1836-1847. doi: 10.1016/j.ymthe.2019.06.015. Epub 2019 Jul 10. Mol Ther. 2019. PMID: 31331814 Free PMC article.

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AAV9 Gene Therapy Increases Lifespan and Treats Pathological and Behavioral Abnormalities in a Mouse Model of CLN8-Batten Disease.

Johnson TB, White KA, Brudvig JJ, Cain JT, Langin L, Pratt MA, Booth CD, Timm DJ, Davis SS, Meyerink B, Likhite S, Meyer K, Weimer JM. Johnson TB, et al. Among authors: timm dj. Mol Ther. 2021 Jan 6;29(1):162-175. doi: 10.1016/j.ymthe.2020.09.033. Epub 2020 Sep 24. Mol Ther. 2021. PMID: 33010819 Free PMC article.

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Searching for novel biomarkers using a mouse model of CLN3-Batten disease.

Timm D, Cain JT, Geraets RD, White KA, Koh SY, Kielian T, Pearce DA, Hastings ML, Weimer JM. Timm D, et al. PLoS One. 2018 Aug 7;13(8):e0201470. doi: 10.1371/journal.pone.0201470. eCollection 2018. PLoS One. 2018. PMID: 30086172 Free PMC article.

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Short-Term Administration of Mycophenolate Is Well-Tolerated in CLN3 Disease (Juvenile Neuronal Ceroid Lipofuscinosis).

Augustine EF, Beck CA, Adams HR, Defendorf S, Vierhile A, Timm D, Weimer JM, Mink JW, Marshall FJ. Augustine EF, et al. Among authors: timm d. JIMD Rep. 2019;43:117-124. doi: 10.1007/8904_2018_113. Epub 2018 Jun 20. JIMD Rep. 2019. PMID: 29923092 Free PMC article.

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A multimodal approach to identify clinically relevant biomarkers to comprehensively monitor disease progression in a mouse model of pediatric neurodegenerative disease.

Johnson TB, Brudvig JJ, Lehtimäki KK, Cain JT, White KA, Bragge T, Rytkönen J, Huhtala T, Timm D, Vihma M, Puoliväli JT, Poutiainen P, Nurmi A, Weimer JM. Johnson TB, et al. Among authors: timm d. Prog Neurobiol. 2020 Jun;189:101789. doi: 10.1016/j.pneurobio.2020.101789. Epub 2020 Mar 18. Prog Neurobiol. 2020. PMID: 32198061

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Enhanced mTOR complex 1 signaling attenuates diabetic cardiac injury in OVE26 mice.

Xu X, Kobayashi S, Timm D, Huang Y, Zhao F, Shou W, Liang Q. Xu X, et al. Among authors: timm d. FASEB J. 2019 Nov;33(11):12800-12811. doi: 10.1096/fj.201901206R. Epub 2019 Aug 30. FASEB J. 2019. PMID: 31469601

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Diminished autophagy limits cardiac injury in mouse models of type 1 diabetes.

Xu X, Kobayashi S, Chen K, Timm D, Volden P, Huang Y, Gulick J, Yue Z, Robbins J, Epstein PN, Liang Q. Xu X, et al. Among authors: timm d. J Biol Chem. 2013 Jun 21;288(25):18077-92. doi: 10.1074/jbc.M113.474650. Epub 2013 May 8. J Biol Chem. 2013. PMID: 23658055 Free PMC article.

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