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Levodopa Added to Stroke Rehabilitation: The ESTREL Randomized Clinical Trial.
Engelter ST, Kaufmann JE, Zietz A, Luft AR, Polymeris A, Altersberger VL, Wiesner K, Wiegert M, Held JPO, Rottenberger Y, Schwarz A, Medlin F, Accolla EA, Foucras S, Kägi G, De Marchis GM, Politz S, Greulich M, Tarnutzer AA, Sturzenegger R, Katan M, Fischer U, Nedeltchev K, Schär J, Van Den Keybus Deglon K, Rapin PA, Salerno A, Seiffge DJ, Auer E, Lippert J, Bonati LH, Schuster-Amft C, Gäumann S, Chabwine JN, Humm A, Möller JC, Schweinfurther R, Bujan B, Jedrysiak P, Sandor PS, Gonzenbach R, Mylius V, Lutz D, Lienert C, Peters N, Michel P, Müri RM, Schädelin S, Hemkens LG, Ford GA, Lyrer PA, Gensicke H, Traenka C; ESTREL Investigators. Engelter ST, et al. Among authors: lutz d. JAMA. 2025 Nov 4;334(17):1523-1532. doi: 10.1001/jama.2025.15185. JAMA. 2025. PMID: 40982270 Free PMC article. Clinical Trial.
The impact of levodopa on post-stroke depression: the ESTREL-depression-study.
Sauter MI, Kaufmann JE, Boos L, Zietz A, Trüssel S, Luft AR, Polymeris A, Altersberger VL, Wiesner K, Wiegert M, Held JPO, Rottenberger Y, Schwarz A, Medlin F, Accolla EA, Foucras S, Kägi G, De Marchis GM, Politz S, Greulich M, Tarnutzer AA, Sturzenegger R, Katan M, Arnold M, Nedeltchev K, Schär J, Deglon KVDK, Rapin PA, Salerno A, Seiffge DJ, Auer E, Lippert J, Bonati LH, Schuster-Amft C, Gäumann S, Chabwine JN, Humm A, Möller JC, Schweinfurther R, Bujan B, Jedrysiak P, Sandor PS, Gonzenbach R, Mylius V, Lutz D, Lienert C, Peters N, Michel P, Müri RM, Schädelin S, Hemkens LG, Ford GA, Lyrer PA, Gensicke H, Traenka C, Engelter ST. Sauter MI, et al. Among authors: lutz d. Eur Stroke J. 2026 Feb 9;11(2):aakag001. doi: 10.1093/esj/aakag001. Eur Stroke J. 2026. PMID: 41701756 Free PMC article. Clinical Trial.
ESTREL-Fatigue-association of levodopa with post-stroke fatigue.
Boos L, Kaufmann JE, Sauter MI, Lyrer P, Zietz A, Trüssel S, Engelter SV, Luft AR, Polymeris A, Altersberger VL, Wiesner K, Held JPO, Rottenberger Y, Schwarz A, Medlin F, Accolla EA, Foucras S, Kägi G, De Marchis GM, Politz S, Greulich M, Tarnutzer AA, Sturzenegger R, Katan M, Fischer U, Nedeltchev K, Schär J, Deglon KVDK, Rapin PA, Salerno A, Seiffge D, Auer E, Lippert J, Bonati LH, Schuster-Amft C, Gäumann S, Chabwine JN, Humm AM, Möller JC, Schweinfurther R, Bujan B, Jedrysiak P, Sandor PS, Gonzenbach R, Veit M, Lutz D, Lienert C, Peters N, Strambo D, Müri RM, Schädelin S, Hemkens LG, Ford GA, Kuppuswamy A, Lerdal A, Simpson DB, English C, Blackwell S, Gensicke H, Traenka C, Engelter ST. Boos L, et al. Among authors: lutz d. Eur Stroke J. 2026 Mar 1;11(4):aakag029. doi: 10.1093/esj/aakag029. Eur Stroke J. 2026. PMID: 41947565 Free PMC article. Clinical Trial.