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Novel cell death signaling pathways in neurotoxicity models of dopaminergic degeneration: relevance to oxidative stress and neuroinflammation in Parkinson's disease.
Kanthasamy A, Jin H, Mehrotra S, Mishra R, Kanthasamy A, Rana A. Kanthasamy A, et al. Among authors: rana a. Neurotoxicology. 2010 Sep;31(5):555-61. doi: 10.1016/j.neuro.2009.12.003. Epub 2009 Dec 11. Neurotoxicology. 2010. PMID: 20005250 Free PMC article. Review.
This review summarizes two novel signaling pathways of nigral dopaminergic degeneration that have been elucidated using neurotoxicity models of PD. Dr. Anumantha Kanthasamy described a cell death pathway involving the novel protein kinase C delta isoform (PKCdelta) in oxid …
This review summarizes two novel signaling pathways of nigral dopaminergic degeneration that have been elucidated using neurotoxicity models …
Emerging neurotoxic mechanisms in environmental factors-induced neurodegeneration.
Kanthasamy A, Jin H, Anantharam V, Sondarva G, Rangasamy V, Rana A, Kanthasamy A. Kanthasamy A, et al. Among authors: rana a. Neurotoxicology. 2012 Aug;33(4):833-7. doi: 10.1016/j.neuro.2012.01.011. Epub 2012 Feb 7. Neurotoxicology. 2012. PMID: 22342404 Free PMC article.
Dr. Arthi Kanthasamy illustrated the role of autophagy as a key determinant in cell death events during neurotoxic insults. Dr. Ajay Rana provided evidence for posttranslational modification of alpha-synuclein protein by the Mixed Linage Kinase (MLK) group of kinase
Dr. Arthi Kanthasamy illustrated the role of autophagy as a key determinant in cell death events during neurotoxic insults. Dr